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WO2002031125A3 - Human phospholipase a2-like enzyme - Google Patents

Human phospholipase a2-like enzyme Download PDF

Info

Publication number
WO2002031125A3
WO2002031125A3 PCT/EP2001/011703 EP0111703W WO0231125A3 WO 2002031125 A3 WO2002031125 A3 WO 2002031125A3 EP 0111703 W EP0111703 W EP 0111703W WO 0231125 A3 WO0231125 A3 WO 0231125A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
human phospholipase
reagents
phospholipase
ameliorating
Prior art date
Application number
PCT/EP2001/011703
Other languages
French (fr)
Other versions
WO2002031125A2 (en
Inventor
Zhimin Zhu
Original Assignee
Bayer Ag
Zhimin Zhu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Zhimin Zhu filed Critical Bayer Ag
Priority to AU2002224774A priority Critical patent/AU2002224774A1/en
Publication of WO2002031125A2 publication Critical patent/WO2002031125A2/en
Publication of WO2002031125A3 publication Critical patent/WO2002031125A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents which regulate human phospholipase A2-like enzyme and reagents which bind to human phospholipase A2-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, asthma, cancer, inflammation, CNS disorders, cardiovascular disorders, chronic obstructive pulmonary disease, diabetes, and obesity.
PCT/EP2001/011703 2000-10-10 2001-10-10 Human phospholipase a2-like enzyme WO2002031125A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002224774A AU2002224774A1 (en) 2000-10-10 2001-10-10 Human phospholipase a2-like enzyme

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23843300P 2000-10-10 2000-10-10
US60/238,433 2000-10-10
US25805200P 2000-12-27 2000-12-27
US60/258,052 2000-12-27

Publications (2)

Publication Number Publication Date
WO2002031125A2 WO2002031125A2 (en) 2002-04-18
WO2002031125A3 true WO2002031125A3 (en) 2002-12-27

Family

ID=26931668

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/011703 WO2002031125A2 (en) 2000-10-10 2001-10-10 Human phospholipase a2-like enzyme

Country Status (2)

Country Link
AU (1) AU2002224774A1 (en)
WO (1) WO2002031125A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001290240A1 (en) 2000-09-19 2002-04-02 Kyowa Hakko Kogyo Co. Ltd. Polypeptide having phospholipase a2 actiivty
CA3050151C (en) * 2003-11-26 2023-03-07 Celera Corporation Single nucleotide polymorphisms associated with cardiovascular disorders and statin response, methods of detection and uses thereof
WO2011100639A2 (en) * 2010-02-11 2011-08-18 Indiana University Research And Technology Corporation Pla2activity as a marker for ovarian and other gynecologic cancers

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197569B1 (en) * 1996-03-29 2001-03-06 Eli Lilly And Company Human phospholipase A2 and related nucleic acid compounds
WO2001053326A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Methods and materials relating to phospholipase-like polypeptides and polynucleotides
WO2002031162A2 (en) * 2000-10-10 2002-04-18 Bayer Aktiengesellschaft Regulation of human phospholipase a2-like enzyme
WO2002031160A2 (en) * 2000-10-10 2002-04-18 Bayer Aktiengesellschaft Regulation of human phospholipase a2-like enzyme

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6197569B1 (en) * 1996-03-29 2001-03-06 Eli Lilly And Company Human phospholipase A2 and related nucleic acid compounds
US6242206B1 (en) * 1996-03-29 2001-06-05 Eli Lilly And Company Human phospholipase A2 and related nucleic acid compounds
WO2001053326A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Methods and materials relating to phospholipase-like polypeptides and polynucleotides
WO2002031162A2 (en) * 2000-10-10 2002-04-18 Bayer Aktiengesellschaft Regulation of human phospholipase a2-like enzyme
WO2002031160A2 (en) * 2000-10-10 2002-04-18 Bayer Aktiengesellschaft Regulation of human phospholipase a2-like enzyme

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 18 June 2001 (2001-06-18), XP002212985, retrieved from EBI Database accession no. AR137924 *
DATABASE EMBL [online] 18 June 2002 (2002-06-18), XP002212987, retrieved from EBI Database accession no. AX417785 *
DATABASE EMBL [online] 18 May 2000 (2000-05-18), "Human PLA2 mRNA", XP002212980, retrieved from EBI Database accession no. AAZ88758 *
DATABASE EMBL [online] 2 November 1998 (1998-11-02), "Homo sapiens cPLA2 beta mRNA", XP002212982, retrieved from EBI Database accession no. AF065215 *
DATABASE EMBL [online] 2 November 1998 (1998-11-02), "Homo sapiens cPLA2 beta precursor RNA", XP002212981, retrieved from EBI Database accession no. AF065216 *
DATABASE EMBL [online] 24 September 2001 (2001-09-24), "Human cytosolic PLA2 beta cDNA", XP002212984, retrieved from EBI Database accession no. AAD11385 *
DATABASE EMBL [online] 25 May 1999 (1999-05-25), "Homo sapiens cPLA2 beta mRNA", XP002212983, retrieved from EBI Database accession no. AF121908 *
DATABASE EMBL [online] 6 July 2002 (2002-07-06), XP002213000, retrieved from EBI Database accession no. AX453671 *
DATABASE EMBL [online] 9 August 2001 (2001-08-09), XP002212986, retrieved from EBI Database accession no. AR156371 *
DENNIS E A: "The growing phospholipase A2 superfamily of signal transduction enzymes", TIBS TRENDS IN BIOCHEMICAL SCIENCES, ELSEVIER PUBLICATION, CAMBRIDGE, EN, vol. 22, no. 1, 1997, pages 1 - 2, XP004016851, ISSN: 0968-0004 *

Also Published As

Publication number Publication date
WO2002031125A2 (en) 2002-04-18
AU2002224774A1 (en) 2002-04-22

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