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WO2002000704A3 - Regulation of human phospholipase c-like enzyme - Google Patents

Regulation of human phospholipase c-like enzyme Download PDF

Info

Publication number
WO2002000704A3
WO2002000704A3 PCT/EP2001/007360 EP0107360W WO0200704A3 WO 2002000704 A3 WO2002000704 A3 WO 2002000704A3 EP 0107360 W EP0107360 W EP 0107360W WO 0200704 A3 WO0200704 A3 WO 0200704A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
human phospholipase
regulation
reagents
phospholipase
Prior art date
Application number
PCT/EP2001/007360
Other languages
French (fr)
Other versions
WO2002000704A2 (en
Inventor
Shyam Ramakrishnan
Original Assignee
Bayer Ag
Shyam Ramakrishnan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Shyam Ramakrishnan filed Critical Bayer Ag
Priority to AU2001270599A priority Critical patent/AU2001270599A1/en
Publication of WO2002000704A2 publication Critical patent/WO2002000704A2/en
Publication of WO2002000704A3 publication Critical patent/WO2002000704A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents which regulate human phospholipase C-like enzyme and reagents which bind to human phospholipase C-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, CNS diseases, and chronic obstructive pulmonary disease.
PCT/EP2001/007360 2000-06-29 2001-06-28 Regulation of human phospholipase c-like enzyme WO2002000704A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001270599A AU2001270599A1 (en) 2000-06-29 2001-06-28 Regulation of human phospholipase c-like enzyme

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21511900P 2000-06-29 2000-06-29
US60/215,119 2000-06-29
US27976501P 2001-03-30 2001-03-30
US60/279,765 2001-03-30

Publications (2)

Publication Number Publication Date
WO2002000704A2 WO2002000704A2 (en) 2002-01-03
WO2002000704A3 true WO2002000704A3 (en) 2002-06-13

Family

ID=26909717

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007360 WO2002000704A2 (en) 2000-06-29 2001-06-28 Regulation of human phospholipase c-like enzyme

Country Status (2)

Country Link
AU (1) AU2001270599A1 (en)
WO (1) WO2002000704A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103130714B (en) * 2012-11-02 2015-06-17 西南科技大学 Fullerene radical malonamide benzyloxy-pyridone derivative and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058675A2 (en) * 1998-05-14 1999-11-18 Chiron Corporation Human genes and gene expression products v
WO2001075121A2 (en) * 2000-03-31 2001-10-11 Millennium Pharmaceuticals, Inc. 16836, a human phospholipase c family member and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058675A2 (en) * 1998-05-14 1999-11-18 Chiron Corporation Human genes and gene expression products v
WO2001075121A2 (en) * 2000-03-31 2001-10-11 Millennium Pharmaceuticals, Inc. 16836, a human phospholipase c family member and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 6 January 2000 (2000-01-06), STRAUSBERG, R.: "xu21b07.x1 NCI_CGAP_Co14 Homo sapiens cDNA clone IMAGE:2800789 3' similar to WP:F31B12.1 CE03281 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C ;, mRNA sequence.", XP002195079 *
LOPEZ ISABEL ET AL: "A novel bifunctional phospholipase C that is regulated by Galpha12 and stimulates the Ras/mitogen-activated protein kinase pathway.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 4, 26 January 2001 (2001-01-26), pages 2758 - 2765, XP002195078, ISSN: 0021-9258 *
SONG CHUNHUA ET AL: "Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 4, 5 October 2000 (2000-10-05), pages 2752 - 2757, XP002195077, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
WO2002000704A2 (en) 2002-01-03
AU2001270599A1 (en) 2002-01-08

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