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WO2002026996A3 - Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme - Google Patents

Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme Download PDF

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Publication number
WO2002026996A3
WO2002026996A3 PCT/EP2001/011012 EP0111012W WO0226996A3 WO 2002026996 A3 WO2002026996 A3 WO 2002026996A3 EP 0111012 W EP0111012 W EP 0111012W WO 0226996 A3 WO0226996 A3 WO 0226996A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
specific phospholipase
human phosphatidylinositol
regulation
reagents
Prior art date
Application number
PCT/EP2001/011012
Other languages
French (fr)
Other versions
WO2002026996A2 (en
Inventor
Zhimin Zhu
Original Assignee
Bayer Ag
Zhimin Zhu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Zhimin Zhu filed Critical Bayer Ag
Priority to AU2002210514A priority Critical patent/AU2002210514A1/en
Publication of WO2002026996A2 publication Critical patent/WO2002026996A2/en
Publication of WO2002026996A3 publication Critical patent/WO2002026996A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reagents which regulate human phosphatidylinositol-specific phospholipase C-like enzyme and reagents which bind to human phosphatidylinositol-specific phospholipase C-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, asthma, cancer, CNS disorders, and chronic obstructive pulmonary disease.
PCT/EP2001/011012 2000-09-27 2001-09-24 Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme WO2002026996A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002210514A AU2002210514A1 (en) 2000-09-27 2001-09-24 Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23555200P 2000-09-27 2000-09-27
US60/235,552 2000-09-27

Publications (2)

Publication Number Publication Date
WO2002026996A2 WO2002026996A2 (en) 2002-04-04
WO2002026996A3 true WO2002026996A3 (en) 2002-09-26

Family

ID=22885960

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/011012 WO2002026996A2 (en) 2000-09-27 2001-09-24 Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme

Country Status (2)

Country Link
AU (1) AU2002210514A1 (en)
WO (1) WO2002026996A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127206D0 (en) * 2001-11-13 2002-01-02 Univ Liverpool Treatment of inflammatory conditions
AU2003242759A1 (en) * 2002-06-26 2004-01-19 Bayer Healthcare Ag Regulation of human phospholipase c-like protein
US20100284992A1 (en) * 2006-10-02 2010-11-11 The Regents Of The University Of Colorado, A Body Corporate Phospholipase C and Method of Use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE SWISSPROT [online] 1 July 1989 (1989-07-01), SUH ET AL.: "1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11) (PLC-DELTA-1) (PHOSPHOLIPASE C-DELTA-1) (PLC-III).", XP002199648, Database accession no. P10688 *
DATABASE SWISSPROT [online] 1 May 2000 (2000-05-01), KIKUNO ET AL.: "KIAA1069 Protein (Fragment)", XP002199647, Database accession no. Q9UPT3 *
KIKUNO ET AL.: "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.", DNA RESEARCH, vol. 6, 1999, pages 197 - 205, XP000852618 *

Also Published As

Publication number Publication date
AU2002210514A1 (en) 2002-04-08
WO2002026996A2 (en) 2002-04-04

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