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WO2002006454A3 - Regulation of human carboxylesterase-like enzyme - Google Patents

Regulation of human carboxylesterase-like enzyme Download PDF

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Publication number
WO2002006454A3
WO2002006454A3 PCT/EP2001/007919 EP0107919W WO0206454A3 WO 2002006454 A3 WO2002006454 A3 WO 2002006454A3 EP 0107919 W EP0107919 W EP 0107919W WO 0206454 A3 WO0206454 A3 WO 0206454A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
human carboxylesterase
regulation
reagents
carboxylesterase
Prior art date
Application number
PCT/EP2001/007919
Other languages
French (fr)
Other versions
WO2002006454A2 (en
Inventor
Yonghong Xiao
Original Assignee
Bayer Ag
Yonghong Xiao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Yonghong Xiao filed Critical Bayer Ag
Priority to AU2001281969A priority Critical patent/AU2001281969A1/en
Publication of WO2002006454A2 publication Critical patent/WO2002006454A2/en
Publication of WO2002006454A3 publication Critical patent/WO2002006454A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Reagents which regulate human carboxylesterase-like enzyme and reagents which bind to human carboxylesterase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, organophosphorus intoxication, cancer, and osteoporosis.
PCT/EP2001/007919 2000-07-17 2001-07-10 Regulation of human carboxylesterase-like enzyme WO2002006454A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001281969A AU2001281969A1 (en) 2000-07-17 2001-07-10 Regulation of human carboxylesterase-like enzyme

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21856400P 2000-07-17 2000-07-17
US60/218,564 2000-07-17

Publications (2)

Publication Number Publication Date
WO2002006454A2 WO2002006454A2 (en) 2002-01-24
WO2002006454A3 true WO2002006454A3 (en) 2002-07-11

Family

ID=22815598

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007919 WO2002006454A2 (en) 2000-07-17 2001-07-10 Regulation of human carboxylesterase-like enzyme

Country Status (2)

Country Link
AU (1) AU2001281969A1 (en)
WO (1) WO2002006454A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1348023A2 (en) 2000-12-18 2003-10-01 Millennium Pharmaceuticals, Inc. 53010, a human carboxylesterase family member and uses thereof
KR100975852B1 (en) 2008-03-14 2010-08-13 연세대학교 산학협력단 Liver cancer diagnostic composition comprising an antibody that specifically binds to liver-carboxyesterase 1 protein

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001057272A2 (en) * 2000-02-04 2001-08-09 Aeomica, Inc. Human genome-derived single exon nucleic acid probes useful for analysis of gene expression in human placenta

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001057272A2 (en) * 2000-02-04 2001-08-09 Aeomica, Inc. Human genome-derived single exon nucleic acid probes useful for analysis of gene expression in human placenta

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 30 April 2001 (2001-04-30), HASHIMOTO, K. ET AL.: "Macaca fascicularis brain cDNA clone:QtrA-12316, full insert sequence.", XP002197703, Database accession no. AB060873 *
DATABASE EMBL [online] 8 July 1999 (1999-07-08), STRAUSBERG, R.: "wf67d05.x1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone IMAGE:2360649 3' similar to TR:Q16859 Q16859 CARBOXYLESTERASE ;, mRNA sequence.", XP002197702, Database accession no. AI808985 *
SCHWER H ET AL: "MOLECULAR CLONING AND CHARACTERIZATION OF A NOVEL PUTATIVE CARBOXYLESTERASE, PRESENT IN HUMAN INTESTINE AND LIVER", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 233, no. 1, 1997, pages 117 - 120, XP000891817, ISSN: 0006-291X *

Also Published As

Publication number Publication date
AU2001281969A1 (en) 2002-01-30
WO2002006454A2 (en) 2002-01-24

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