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WO2002000704A3 - Regulation d'une enzyme du type phospholipase c humaine - Google Patents

Regulation d'une enzyme du type phospholipase c humaine Download PDF

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Publication number
WO2002000704A3
WO2002000704A3 PCT/EP2001/007360 EP0107360W WO0200704A3 WO 2002000704 A3 WO2002000704 A3 WO 2002000704A3 EP 0107360 W EP0107360 W EP 0107360W WO 0200704 A3 WO0200704 A3 WO 0200704A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
human phospholipase
regulation
reagents
phospholipase
Prior art date
Application number
PCT/EP2001/007360
Other languages
English (en)
Other versions
WO2002000704A2 (fr
Inventor
Shyam Ramakrishnan
Original Assignee
Bayer Ag
Shyam Ramakrishnan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Shyam Ramakrishnan filed Critical Bayer Ag
Priority to AU2001270599A priority Critical patent/AU2001270599A1/en
Publication of WO2002000704A2 publication Critical patent/WO2002000704A2/fr
Publication of WO2002000704A3 publication Critical patent/WO2002000704A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des réactifs régulant une enzyme du type phospholipase C humaine ainsi que des réactifs se liant aux produits génétiques de cette enzyme du type phospholipase C humaine. Ces réactifs peuvent intervenir dans la prévention, le traitement ou la correction de dysfonctionnements ou de maladies, et notamment du cancer, des maladies du système nerveux central (SNC) et de la bronchopneumopathie chronique obstructive, entre autres.
PCT/EP2001/007360 2000-06-29 2001-06-28 Regulation d'une enzyme du type phospholipase c humaine WO2002000704A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001270599A AU2001270599A1 (en) 2000-06-29 2001-06-28 Regulation of human phospholipase c-like enzyme

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21511900P 2000-06-29 2000-06-29
US60/215,119 2000-06-29
US27976501P 2001-03-30 2001-03-30
US60/279,765 2001-03-30

Publications (2)

Publication Number Publication Date
WO2002000704A2 WO2002000704A2 (fr) 2002-01-03
WO2002000704A3 true WO2002000704A3 (fr) 2002-06-13

Family

ID=26909717

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007360 WO2002000704A2 (fr) 2000-06-29 2001-06-28 Regulation d'une enzyme du type phospholipase c humaine

Country Status (2)

Country Link
AU (1) AU2001270599A1 (fr)
WO (1) WO2002000704A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103130714B (zh) * 2012-11-02 2015-06-17 西南科技大学 富勒烯基丙二酰胺苄氧基吡啶酮衍生物及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058675A2 (fr) * 1998-05-14 1999-11-18 Chiron Corporation Genes humains et produits d'expression genique v
WO2001075121A2 (fr) * 2000-03-31 2001-10-11 Millennium Pharmaceuticals, Inc. 16836, un nouvel element de la famille de la phospholipase c humaine et ses utilisations

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058675A2 (fr) * 1998-05-14 1999-11-18 Chiron Corporation Genes humains et produits d'expression genique v
WO2001075121A2 (fr) * 2000-03-31 2001-10-11 Millennium Pharmaceuticals, Inc. 16836, un nouvel element de la famille de la phospholipase c humaine et ses utilisations

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 6 January 2000 (2000-01-06), STRAUSBERG, R.: "xu21b07.x1 NCI_CGAP_Co14 Homo sapiens cDNA clone IMAGE:2800789 3' similar to WP:F31B12.1 CE03281 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C ;, mRNA sequence.", XP002195079 *
LOPEZ ISABEL ET AL: "A novel bifunctional phospholipase C that is regulated by Galpha12 and stimulates the Ras/mitogen-activated protein kinase pathway.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 4, 26 January 2001 (2001-01-26), pages 2758 - 2765, XP002195078, ISSN: 0021-9258 *
SONG CHUNHUA ET AL: "Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 4, 5 October 2000 (2000-10-05), pages 2752 - 2757, XP002195077, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
WO2002000704A2 (fr) 2002-01-03
AU2001270599A1 (en) 2002-01-08

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