WO2006010497A3 - Diagnostics et therapeutiques pour des maladies associees a choline kinase (chk) - Google Patents
Diagnostics et therapeutiques pour des maladies associees a choline kinase (chk) Download PDFInfo
- Publication number
- WO2006010497A3 WO2006010497A3 PCT/EP2005/007706 EP2005007706W WO2006010497A3 WO 2006010497 A3 WO2006010497 A3 WO 2006010497A3 EP 2005007706 W EP2005007706 W EP 2005007706W WO 2006010497 A3 WO2006010497 A3 WO 2006010497A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- diseases
- chk
- therapeutics
- diagnostics
- diseases associated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
- G01N2333/91215—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases with a definite EC number (2.7.1.-)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
L'invention porte sur une CHK humaine associée à des maladies cardio-vasculaires, des infections, des maladies dermatologiques, des maladies endocrinologiques, des maladies métaboliques, des maladies gastroentérologiques, des cancers des inflammations, des maladies hématologiques, des maladies respiratoires, des maladies du squelette musculaires, des maladies neurologiques, des maladies urologiques. Cette invention concerne également des dosages pour l'identification de composés utiles dans le traitement ou la prévention de maladies cardio-vasculaires, d'infections, de maladies dermatologiques, de maladies endocrinologiques, des maladies métaboliques, des maladies gastroentérologiques, des cancers des inflammations, des maladies hématologiques, des maladies respiratoires, des maladies du squelette musculaires, des maladies neurologiques, des maladies urologiques. Cette invention se rapporte aussi à des composés qui se lient à CHK et/ou activent ou inhibent l'activité de CHK, ainsi qu'à des compositions pharmaceutiques contenant ces composés.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04017827 | 2004-07-28 | ||
| EP04017827.9 | 2004-07-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2006010497A2 WO2006010497A2 (fr) | 2006-02-02 |
| WO2006010497A3 true WO2006010497A3 (fr) | 2006-03-23 |
Family
ID=35044742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2005/007706 WO2006010497A2 (fr) | 2004-07-28 | 2005-07-15 | Diagnostics et therapeutiques pour des maladies associees a choline kinase (chk) |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2006010497A2 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007138143A2 (fr) * | 2006-05-29 | 2007-12-06 | Consejo Superior De Investigaciones Cientificas | Anticorps monoclonaux anti-choline kinase alpha et leur application dans des techniques d'analyse, de diagnostic du cancer et dans la préparation de médicaments |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003070883A2 (fr) * | 2002-02-15 | 2003-08-28 | Millennium Pharmaceuticals, Inc. | Methodes et compositions pour le traitement du sida et de troubles associes au vih faisant appel a des molecules 1414, 1481, 1553, 34021, 1720, 1683, 1552, 1682, 1675, 12825, 9952, 5816, 10002, 1611, 1371, 14324, 126, 270, 312, 167, 326, 18926, 6747, 1793, 1784, ou 2045. |
-
2005
- 2005-07-15 WO PCT/EP2005/007706 patent/WO2006010497A2/fr active Application Filing
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003070883A2 (fr) * | 2002-02-15 | 2003-08-28 | Millennium Pharmaceuticals, Inc. | Methodes et compositions pour le traitement du sida et de troubles associes au vih faisant appel a des molecules 1414, 1481, 1553, 34021, 1720, 1683, 1552, 1682, 1675, 12825, 9952, 5816, 10002, 1611, 1371, 14324, 126, 270, 312, 167, 326, 18926, 6747, 1793, 1784, ou 2045. |
Non-Patent Citations (3)
| Title |
|---|
| CALLEWAERT NICO ET AL: "Noninvasive diagnosis of liver cirrhosis using DNA sequencer-based total serum protein glycomics", NATURE MEDICINE, vol. 10, no. 4, April 2004 (2004-04-01), pages 429 - 434, XP002348864, ISSN: 1078-8956 * |
| DATABASE Geneseq [online] 29 January 2004 (2004-01-29), "Human choline kinase (gene ID 9952) protein.", XP002348866, retrieved from EBI accession no. GSP:ADE40443 Database accession no. ADE40443 * |
| RAMÍREZ DE MOLINA A ET AL: "OVEREXORESSION OF CHOLINE KINASE IS A FREQUENT FEATURE IN HUMAN TIMOR-DERIVED CELL LINES AND IN LUNG, PROSTATE, AND COLORECTAL HUMAN CANCERS", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS, SAN DIEGO, CA, US, vol. 296, no. 3, 23 August 2002 (2002-08-23), pages 580 - 583, XP001182226, ISSN: 0006-291X * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006010497A2 (fr) | 2006-02-02 |
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