+

WO2009031642A1 - 医薬組成物 - Google Patents

医薬組成物 Download PDF

Info

Publication number
WO2009031642A1
WO2009031642A1 PCT/JP2008/066056 JP2008066056W WO2009031642A1 WO 2009031642 A1 WO2009031642 A1 WO 2009031642A1 JP 2008066056 W JP2008066056 W JP 2008066056W WO 2009031642 A1 WO2009031642 A1 WO 2009031642A1
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
mass
general formula
halogen
alcohol
Prior art date
Application number
PCT/JP2008/066056
Other languages
English (en)
French (fr)
Inventor
Takaaki Masuda
Naoko Kobayashi
Hideaki Sasagawa
Original Assignee
Pola Pharma Inc.
Nihon Nohyaku Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pola Pharma Inc., Nihon Nohyaku Co., Ltd. filed Critical Pola Pharma Inc.
Priority to US12/676,346 priority Critical patent/US20100204293A1/en
Priority to JP2009531290A priority patent/JP5529539B2/ja
Priority to CN2008801059132A priority patent/CN101808637B/zh
Priority to EP08829061.4A priority patent/EP2191826B1/en
Publication of WO2009031642A1 publication Critical patent/WO2009031642A1/ja
Priority to US13/603,220 priority patent/US8513296B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

一般式（１）で示される化合物と、アルコールを５０～９５質量％と、水及び／又はアニオン性界面活性剤を０．１～３５質量％と、を含有することを特徴とする、抗真菌用外用剤。Ｘ＝ハロゲンまたはＨ　一般式（１）
PCT/JP2008/066056 2007-09-05 2008-09-05 医薬組成物 WO2009031642A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US12/676,346 US20100204293A1 (en) 2007-09-05 2008-09-05 Pharmaceutical composition
JP2009531290A JP5529539B2 (ja) 2007-09-05 2008-09-05 医薬組成物
CN2008801059132A CN101808637B (zh) 2007-09-05 2008-09-05 医药组合物
EP08829061.4A EP2191826B1 (en) 2007-09-05 2008-09-05 Pharmaceutical composition
US13/603,220 US8513296B2 (en) 2007-09-05 2012-09-04 Pharmaceutical composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-229619 2007-09-05
JP2007229619 2007-09-05

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/676,346 A-371-Of-International US20100204293A1 (en) 2007-09-05 2008-09-05 Pharmaceutical composition
US13/603,220 Continuation US8513296B2 (en) 2007-09-05 2012-09-04 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
WO2009031642A1 true WO2009031642A1 (ja) 2009-03-12

Family

ID=40428954

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/066056 WO2009031642A1 (ja) 2007-09-05 2008-09-05 医薬組成物

Country Status (6)

Country Link
US (2) US20100204293A1 (ja)
EP (1) EP2191826B1 (ja)
JP (1) JP5529539B2 (ja)
KR (1) KR20100075475A (ja)
CN (1) CN101808637B (ja)
WO (1) WO2009031642A1 (ja)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120149745A1 (en) * 2009-08-25 2012-06-14 Nihon Nohyaku Co., Ltd. Antimycotic pharmaceutical composition
JP2012523410A (ja) * 2009-04-09 2012-10-04 株式会社ポーラファルマ 抗真菌医薬組成物
JP2013528157A (ja) * 2010-06-11 2013-07-08 株式会社ポーラファルマ 抗真菌医薬組成物
JP2013545819A (ja) * 2010-12-16 2013-12-26 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 非経口投与のためのアゾール医薬製剤ならびにその調製方法およびアゾール化合物に対して感受性の疾患の処置としてのその使用方法
WO2014042043A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Pharmaceutical composition containing luliconazole
WO2014041825A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Amide derivative and use of the same as stability index of a luliconazole pharmaceutical formulation
WO2014042231A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Crystal and pharmaceutical preparation containing the same crystal
WO2014041708A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal
WO2014041846A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Use of surface free energy for differential evaluation of crystal, crystal evaluated on basis of surface free energy as index, and phrmaceutical composition prepared by containing the crystal
WO2014136282A1 (en) 2013-03-08 2014-09-12 Pola Pharma Inc. Crystalline form having specific crystal habit and pharmaceutical composition|containing this crystalline form as active ingredient
JP2015027983A (ja) * 2013-06-24 2015-02-12 株式会社ポーラファルマ 結晶及び該結晶を含有してなる医薬製剤
WO2015033612A1 (en) 2013-09-06 2015-03-12 Pola Pharma Inc. Crystal having specific crystal habit and pharmaceutical composition containing the crystal as active ingredient
US8980931B1 (en) 2013-12-12 2015-03-17 Pola Pharma Inc. Method of evaluating pharmaceutical preparation containing luliconazole and index substance
JP2015063566A (ja) * 2015-01-06 2015-04-09 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP2018016648A (ja) * 2012-05-11 2018-02-01 ロート製薬株式会社 ルリコナゾール含有外用医薬組成物
US10130610B2 (en) 2009-04-09 2018-11-20 Pola Pharma Inc. Antimycotic pharmaceutical composition
US10548890B2 (en) 2011-04-28 2020-02-04 Platform Brightworks Two, Ltd. Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2025337B1 (en) * 2006-03-08 2014-09-10 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
RU2423128C2 (ru) * 2006-03-08 2011-07-10 Нихон Нохияку Ко., Лтд. Фармацевтическая композиция для наружного применения
JP5184342B2 (ja) * 2006-03-08 2013-04-17 日本農薬株式会社 外用の医薬組成物
WO2009031643A1 (ja) 2007-09-05 2009-03-12 Pola Pharma Inc. 抗真菌組成物
CN101808639B (zh) * 2007-09-05 2012-12-05 宝丽制药股份有限公司 抗真菌医药组合物
KR20100075475A (ko) 2007-09-05 2010-07-02 가부시키가이샤 폴라 파마 의약 조성물
CN102395274B (zh) * 2009-02-13 2014-03-12 托派卡医药股份有限公司 抗真菌制剂
TW201040214A (en) * 2009-04-07 2010-11-16 Holland Colours Nv Additive concentrate for polymers
US9480746B2 (en) * 2014-04-21 2016-11-01 Pola Pharma Inc. Resin container filled with antifungal pharmaceutical composition
CN107865825B (zh) * 2016-09-28 2022-05-20 四川海思科制药有限公司 一种卢立康唑外用喷雾剂药物组合物及其制备方法
US10898470B1 (en) 2019-08-13 2021-01-26 Sato Pharmaceutical Co., Ltd. Pharmaceutical composition containing antifungal agent as active ingredient

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0570351A (ja) 1991-09-17 1993-03-23 Lion Corp 医療用製剤
JPH0665076A (ja) 1992-08-19 1994-03-08 Pola Chem Ind Inc 抗真菌外用剤
WO1997002821A2 (en) 1995-07-08 1997-01-30 Nihon Nohyaku Co., Ltd. Antifungal agent, compound therefor, process for producing the same
JP2000169372A (ja) 1998-09-29 2000-06-20 Takeda Chem Ind Ltd 抗真菌薬組成物
JP2002193755A (ja) * 2000-12-28 2002-07-10 Sansho Seiyaku Co Ltd フケ・カユミ防止頭髪用および洗髪用化粧料
WO2003105841A1 (ja) * 2002-06-18 2003-12-24 ポーラ化成工業株式会社 抗真菌医薬組成物
JP2005154306A (ja) 2003-11-21 2005-06-16 Hisamitsu Pharmaceut Co Inc 抗真菌エアゾール外用製剤
WO2007102242A1 (ja) * 2006-03-08 2007-09-13 Nihon Nohyaku Co., Ltd. 外用の医薬組成物
WO2007102442A1 (ja) 2006-03-05 2007-09-13 Biomedical Research Group Inc. モノクローナル抗体、ハイブリドーマ及びリポ多糖の定量方法

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4267169A (en) * 1978-07-22 1981-05-12 Toko Yakuhin Kogyo Kabushiki Kaisha Novel preparation of clotrimazole
JPS5815909A (ja) 1981-07-22 1983-01-29 Toko Yakuhin Kogyo Kk 抗真菌外用剤
US4636520A (en) * 1984-07-16 1987-01-13 Fujisawa Pharmaceutical Co., Ltd. Antifungal composition employing pyrrolnitrin in combination with an imidazole compound
JPH0236572B2 (ja) 1984-11-13 1990-08-17 Hokuriku Pharmaceutical Suteroidoo177monoesuteruganjukuriimuzai
JPS6293227A (ja) 1985-10-19 1987-04-28 Nippon Nohyaku Co Ltd 抗真菌剤
US4764381A (en) * 1985-12-06 1988-08-16 Key Pharmaceuticals, Inc. Percutaneous penetration enhancer of oleic acid and 2-ethyl-1, 3-hexanediol
JPH0774144B2 (ja) 1986-03-12 1995-08-09 久光製薬株式会社 尿素を含有する皮膚用組成物
US5686489A (en) 1986-12-23 1997-11-11 Tristrata Technology, Inc. Alpha hydroxyacid esters for skin aging
JPH01246219A (ja) 1988-03-25 1989-10-02 Nippon Nohyaku Co Ltd 抗真菌外用クリーム組成物
JPH01242525A (ja) * 1988-03-25 1989-09-27 Nippon Nohyaku Co Ltd 抗真菌外用剤
JP3030780B2 (ja) 1988-12-29 2000-04-10 日本農薬株式会社 光学活性なケテンジチオアセタール誘導体及びその製造方法
JPH02264723A (ja) 1989-04-06 1990-10-29 Taisho Pharmaceut Co Ltd 抗真菌剤
CA2056445A1 (en) 1989-05-26 1990-11-27 Ho-Wah Hui Injectable clarithromycin composition
IL97012A0 (en) 1990-01-30 1992-03-29 Gist Brocades Nv Topical preparations for treating human nails
US5340836A (en) * 1991-02-19 1994-08-23 Mark S. Reinhard Composition and method for treatment of vaginal yeast infections
FR2673537B1 (fr) * 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
JP2555555B2 (ja) 1991-07-03 1996-11-20 武田薬品工業株式会社 抗真菌性外用製剤
JPH06199701A (ja) 1992-12-29 1994-07-19 Lion Corp 外用消炎鎮痛剤
JPH06211651A (ja) 1993-01-12 1994-08-02 Hisamitsu Pharmaceut Co Inc 爪白癬治療用組成物
JPH0774144A (ja) 1993-06-29 1995-03-17 Sony Corp プラズマ装置のクリーニング方法
ATE202694T1 (de) * 1993-07-01 2001-07-15 Yamanouchi Europ Bv Retinoid enthaltende stabile topische zusammensetzungen
DE4337945A1 (de) * 1993-11-06 1995-05-11 Labtec Gmbh Pflaster zur Behandlung von Nagelmykosen
JP2860748B2 (ja) 1993-12-24 1999-02-24 エスエス製薬株式会社 安定な酪酸ヒドロコルチゾン含有クリーム剤
JP3803393B2 (ja) 1994-01-12 2006-08-02 久光製薬株式会社 爪白癬治療用組成物
JP3629283B2 (ja) 1994-02-15 2005-03-16 ポーラ化成工業株式会社 皮膚外用剤
JP3081766B2 (ja) * 1994-05-06 2000-08-28 東興薬品工業株式会社 角質貯留型抗真菌外用組成物
GB9420355D0 (en) * 1994-10-10 1994-11-23 Univ Nottingham Preparation of protein microspheres, films and coatings
AU3673195A (en) 1994-10-13 1996-05-06 Hisamitsu Pharmaceutical Co., Inc. External preparation for nail ringworm
SE9502244D0 (sv) * 1995-06-20 1995-06-20 Bioglan Ab A composition and a process for the preparation thereof
WO1997007794A1 (fr) 1995-08-28 1997-03-06 Showa Yakuhin Kako Co., Ltd. Composition pour anesthesie locale
US5993787A (en) * 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
JP4253047B2 (ja) 1996-09-27 2009-04-08 杏林製薬株式会社 被膜形成性抗真菌剤組成物
JPH10226686A (ja) 1996-12-10 1998-08-25 Nippon Nohyaku Co Ltd 光学活性体である（ｒ）−（ｅ）−（４−置換フェニル−１，３−ジチオラン−２−イリデン）−１−イミダゾールアセトニトリル誘導体及び抗真菌剤及びそれらの製造方法
JP4227677B2 (ja) 1996-12-10 2009-02-18 杏林製薬株式会社 被膜形成性抗真菌剤組成物
WO2000001384A1 (fr) 1998-07-01 2000-01-13 Lead Chemical Co., Ltd. Preparation a base de ketotifene destinee a etre absorbee par voie percutanee
US5962536A (en) * 1998-07-31 1999-10-05 Komer; Gene Injectable propofol formulations
CA2343284C (en) * 1998-09-10 2008-11-18 Ipr-Institute For Pharmaceutical Research Ag Topical application products
US20040208906A1 (en) * 1999-07-12 2004-10-21 Daiichi Suntory Pharma Co., Ltd. Pharmaceutical composition for topical administration
JP2001064206A (ja) 1999-08-30 2001-03-13 Isp Japan Kk 経皮吸収促進組成物
US7074392B1 (en) 2000-03-27 2006-07-11 Taro Pharmaceutical Industries Limited Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections
US6428654B1 (en) 2000-04-05 2002-08-06 Hercules Incorporated Fungicidal method
JP2002114680A (ja) 2000-07-31 2002-04-16 Nippon Nohyaku Co Ltd 抗真菌剤
JP2002284702A (ja) 2001-01-19 2002-10-03 Teika Seiyaku Kk 外用抗真菌製剤
KR100423666B1 (ko) 2001-02-07 2004-03-18 보령제약 주식회사 항진균 외용 제제
US6585963B1 (en) 2001-02-15 2003-07-01 Watson Pharmaceuticals, Inc. Nail compositions and methods of administering same
US20030017207A1 (en) 2001-05-01 2003-01-23 Lin Shun Y. Compositions and methods for treating vulvovaginitis and vaginosis
JP2002363070A (ja) 2001-06-06 2002-12-18 Yuutoku Yakuhin Kogyo Kk 経皮吸収貼付剤
RU2310441C9 (ru) 2001-09-04 2008-03-10 Тромсдорф ГмбХ унд Ко.КГ Арцнаймиттель Способ профилактики и/или лечения дисфункции, и/или нарушения структуры ногтей, пластырь для его осуществления и его применение
JP2003252798A (ja) 2002-02-28 2003-09-10 Shiseido Co Ltd 抗菌ゲル製剤
US6846837B2 (en) * 2002-06-21 2005-01-25 Howard I. Maibach Topical administration of basic antifungal compositions to treat fungal infections of the nails
JP4387639B2 (ja) 2002-07-16 2009-12-16 久光製薬株式会社 経皮吸収製剤
ES2301814T3 (es) 2002-09-05 2008-07-01 Galderma S.A. Solucion para aplicacion ungueal.
US20060140984A1 (en) * 2002-10-25 2006-06-29 Foamix Ltd. Cosmetic and pharmaceutical foam
RU2358718C2 (ru) 2003-03-21 2009-06-20 Нексмед Холдингс, Инк. Противогрибковое покрытие для ногтей и способ его применения
US20070099932A1 (en) * 2003-06-25 2007-05-03 Toshihiro Shirouzu External preparation for athlete's foot treatment
JP2005104924A (ja) * 2003-09-30 2005-04-21 Kobayashi Pharmaceut Co Ltd 外用医薬組成物
JP4429035B2 (ja) 2004-02-27 2010-03-10 久光製薬株式会社 角質貯留性を高めた外用クリーム製剤
JP3783104B2 (ja) 2004-03-31 2006-06-07 小林製薬株式会社 抗真菌性外用組成物
TWI341212B (en) 2004-06-15 2011-05-01 Hisamitsu Pharmaceutical Co Antiinflammatory and pain-relieving agent for external use
JP4690672B2 (ja) 2004-07-20 2011-06-01 岩城製薬株式会社 乳剤性皮膚外用剤
JP3800232B2 (ja) 2004-09-30 2006-07-26 小林製薬株式会社 抗真菌性外用組成物
JP2006306734A (ja) 2005-04-26 2006-11-09 Tsumura & Co 尿素配合外用剤
WO2007077806A1 (ja) 2005-12-28 2007-07-12 Teikoku Seiyaku Co., Ltd. 爪用医薬組成物
JP5184342B2 (ja) 2006-03-08 2013-04-17 日本農薬株式会社 外用の医薬組成物
EP2025337B1 (en) * 2006-03-08 2014-09-10 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
CN101808639B (zh) * 2007-09-05 2012-12-05 宝丽制药股份有限公司 抗真菌医药组合物
WO2009031643A1 (ja) * 2007-09-05 2009-03-12 Pola Pharma Inc. 抗真菌組成物
KR20100075475A (ko) 2007-09-05 2010-07-02 가부시키가이샤 폴라 파마 의약 조성물
CN102395274B (zh) * 2009-02-13 2014-03-12 托派卡医药股份有限公司 抗真菌制剂
WO2010117091A2 (en) * 2009-04-09 2010-10-14 Pola Pharma Inc. Antimycotic pharmaceutical composition
US10130610B2 (en) * 2009-04-09 2018-11-20 Pola Pharma Inc. Antimycotic pharmaceutical composition
CN102481286B (zh) 2009-08-25 2014-02-26 宝丽制药股份有限公司 抗真菌药物组合物

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0570351A (ja) 1991-09-17 1993-03-23 Lion Corp 医療用製剤
JPH0665076A (ja) 1992-08-19 1994-03-08 Pola Chem Ind Inc 抗真菌外用剤
WO1997002821A2 (en) 1995-07-08 1997-01-30 Nihon Nohyaku Co., Ltd. Antifungal agent, compound therefor, process for producing the same
JP2000169372A (ja) 1998-09-29 2000-06-20 Takeda Chem Ind Ltd 抗真菌薬組成物
JP2002193755A (ja) * 2000-12-28 2002-07-10 Sansho Seiyaku Co Ltd フケ・カユミ防止頭髪用および洗髪用化粧料
WO2003105841A1 (ja) * 2002-06-18 2003-12-24 ポーラ化成工業株式会社 抗真菌医薬組成物
JP2005154306A (ja) 2003-11-21 2005-06-16 Hisamitsu Pharmaceut Co Inc 抗真菌エアゾール外用製剤
WO2007102442A1 (ja) 2006-03-05 2007-09-13 Biomedical Research Group Inc. モノクローナル抗体、ハイブリドーマ及びリポ多糖の定量方法
WO2007102242A1 (ja) * 2006-03-08 2007-09-13 Nihon Nohyaku Co., Ltd. 外用の医薬組成物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BORRAS-BLASCO JOAQUIN ET AL.: "A mathematical approach to predicting the percotaneous absorption enhancing effect of sodium lauryl sulfate", INTERNATIONAL JOURNAL OF PHARMACEUTICALS, vol. 269, no. 1, 2004
See also references of EP2191826A4 *

Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012523410A (ja) * 2009-04-09 2012-10-04 株式会社ポーラファルマ 抗真菌医薬組成物
US10130610B2 (en) 2009-04-09 2018-11-20 Pola Pharma Inc. Antimycotic pharmaceutical composition
US9050271B2 (en) 2009-04-09 2015-06-09 Pola Pharma Inc. Antimycotic pharmaceutical composition
US8952044B2 (en) * 2009-08-25 2015-02-10 Pola Pharma Inc. Antimycotic pharmaceutical composition
US20120149745A1 (en) * 2009-08-25 2012-06-14 Nihon Nohyaku Co., Ltd. Antimycotic pharmaceutical composition
JP2015163655A (ja) * 2010-06-11 2015-09-10 株式会社ポーラファルマ 抗真菌医薬組成物
JP2013528157A (ja) * 2010-06-11 2013-07-08 株式会社ポーラファルマ 抗真菌医薬組成物
JP2013545819A (ja) * 2010-12-16 2013-12-26 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 非経口投与のためのアゾール医薬製剤ならびにその調製方法およびアゾール化合物に対して感受性の疾患の処置としてのその使用方法
US10307418B2 (en) 2010-12-16 2019-06-04 Platform Brightworks Two, Ltd. Azole pharmaceutical formulations for parenteral administration and methods for preparing and using the same as treatment of diseases sensitive to azole compounds
JP2017114869A (ja) * 2010-12-16 2017-06-29 プラットフォーム ブライトワークス トゥー， リミテッド 非経口投与のためのアゾール医薬製剤ならびにその調製方法およびアゾール化合物に対して感受性の疾患の処置としてのその使用方法
US11045466B2 (en) 2011-04-28 2021-06-29 Platform Brightworks Two, Ltd. Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
US10548890B2 (en) 2011-04-28 2020-02-04 Platform Brightworks Two, Ltd. Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
JP2020007370A (ja) * 2012-05-11 2020-01-16 ロート製薬株式会社 ルリコナゾール含有外用医薬組成物
JP2018016648A (ja) * 2012-05-11 2018-02-01 ロート製薬株式会社 ルリコナゾール含有外用医薬組成物
US9199977B2 (en) 2012-09-14 2015-12-01 Pola Pharma Inc. Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal
JP5589130B1 (ja) * 2012-09-14 2014-09-10 株式会社ポーラファルマ 結晶及び該結晶を含有してなる医薬製剤
WO2014042043A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Pharmaceutical composition containing luliconazole
WO2014041825A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Amide derivative and use of the same as stability index of a luliconazole pharmaceutical formulation
WO2014042231A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Crystal and pharmaceutical preparation containing the same crystal
WO2014041708A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal
US9012484B2 (en) 2012-09-14 2015-04-21 Pola Pharma Inc. Crystal and pharmaceutical preparation containing the same crystal
WO2014041846A1 (en) 2012-09-14 2014-03-20 Pola Pharma Inc. Use of surface free energy for differential evaluation of crystal, crystal evaluated on basis of surface free energy as index, and phrmaceutical composition prepared by containing the crystal
JP2014074008A (ja) * 2012-09-14 2014-04-24 Pola Pharma Inc 晶癖を有する結晶及び該結晶を加工してなる医薬組成物
US9068958B1 (en) 2012-09-14 2015-06-30 Pola Pharma Inc. Use of surface free energy for differential evaluation of crystal, crystal evaluated on basis of surface free energy as index, and pharmaceutical composition prepared by containing the crystal
JP2014074012A (ja) * 2012-09-14 2014-04-24 Pola Pharma Inc 医薬組成物
JP2014111672A (ja) * 2012-09-14 2014-06-19 Pola Pharma Inc 医薬組成物
US9145401B2 (en) 2012-09-14 2015-09-29 Pola Pharma Inc. Amide derivative and use of the same as stability index of a luliconazole pharmaceutical formulation
US9453006B2 (en) 2013-03-08 2016-09-27 Pola Pharma Inc. Crystalline form having specific crystal habit and pharmaceutical composition containing this crystalline form as active ingredient
WO2014136282A1 (en) 2013-03-08 2014-09-12 Pola Pharma Inc. Crystalline form having specific crystal habit and pharmaceutical composition|containing this crystalline form as active ingredient
JP2015027983A (ja) * 2013-06-24 2015-02-12 株式会社ポーラファルマ 結晶及び該結晶を含有してなる医薬製剤
JP2015091890A (ja) * 2013-06-24 2015-05-14 株式会社ポーラファルマ 結晶及び該結晶を含有してなる医薬製剤
JP2015027984A (ja) * 2013-06-24 2015-02-12 株式会社ポーラファルマ 結晶及び該結晶を含有してなる医薬製剤
US9527836B2 (en) 2013-09-06 2016-12-27 Pola Pharma Inc. Crystal having specific crystal habit and pharmaceutical composition containing the crystal as active ingredient
WO2015033612A1 (en) 2013-09-06 2015-03-12 Pola Pharma Inc. Crystal having specific crystal habit and pharmaceutical composition containing the crystal as active ingredient
US9085554B2 (en) 2013-12-12 2015-07-21 Pola Pharma Inc. Method of evaluating pharmaceutical preparation containing luliconazole and index substance
US8980931B1 (en) 2013-12-12 2015-03-17 Pola Pharma Inc. Method of evaluating pharmaceutical preparation containing luliconazole and index substance
JP2015063566A (ja) * 2015-01-06 2015-04-09 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物

Also Published As

Publication number Publication date
CN101808637A (zh) 2010-08-18
JPWO2009031642A1 (ja) 2010-12-16
CN101808637B (zh) 2013-07-24
US8513296B2 (en) 2013-08-20
JP5529539B2 (ja) 2014-06-25
US20120329845A1 (en) 2012-12-27
US20100204293A1 (en) 2010-08-12
EP2191826B1 (en) 2017-03-08
EP2191826A4 (en) 2010-09-15
EP2191826A1 (en) 2010-06-02
KR20100075475A (ko) 2010-07-02

Similar Documents

Publication Publication Date Title
WO2009031642A1 (ja) 医薬組成物
WO2009031644A1 (ja) 抗真菌医薬組成物
WO2007120980A3 (en) 2,4-pyrimidinediamine compounds for treating or preventing autoimmune diseases
WO2007148185A3 (en) Substituted 3 -amino- pyrrolidino-4 -lactams as dpp inhibitors
UA94833C2 (en) Substituted bicyclolactams
WO2008013838A3 (en) Pyridizinone derivatives
WO2007031933A3 (en) Stable pharmaceutical composition comprising a pyrimidine-sulfamide
WO2007062399A3 (en) Oncogenic ras-specific cytotoxic compound and methods of use thereof
WO2006105127A3 (en) Hydroxysteroid dehydrogenase inhibitors
UA101912C2 (en) Fungicidal composition
WO2007090882A3 (en) Pharmaceutical extended release compositions comprising pramipexole
WO2008022286A3 (en) Small molecule inhibitors of kynurenine-3-monooxygenase
WO2004082822A3 (en) Methods for isolating crystalline form i of 5-azacytidine
WO2008110314A8 (de) Fluoralkylphenylamidine und deren verwendung als fungizide
WO2008128639A8 (de) Thiadiazolyloxyphenylamidine und deren verwendung als fungizide
WO2007019191A3 (en) Thiazolopyrimidine kinase inhibitors
WO2008014955A3 (en) Fungicidal compounds and compositions
WO2007126900A3 (en) Antifungal agents
WO2008034142A3 (en) Synthesis, methods of using, and compositions of cycloalkylmethylamines
WO2005005389A3 (en) Malonamide derivatives
WO2008052379A3 (en) Organic compounds
PT2049480E (pt) Derivados de 2-arilindole como inibidores da mpges-i
WO2009020137A1 (ja) アミノピラゾールアミド誘導体
WO2009051223A1 (ja) 白内障処置のための医薬組成物
WO2009011305A1 (ja) アミド化合物とその植物病害防除方法

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200880105913.2

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08829061

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2009531290

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 12676346

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

REEP Request for entry into the european phase

Ref document number: 2008829061

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2008829061

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 1814/CHENP/2010

Country of ref document: IN

ENP Entry into the national phase

Ref document number: 20107007255

Country of ref document: KR

Kind code of ref document: A

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载