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WO2005078129A3 - Procede pour le diagnostic/pronostic d’une thrombose - Google Patents

Procede pour le diagnostic/pronostic d’une thrombose Download PDF

Info

Publication number
WO2005078129A3
WO2005078129A3 PCT/FR2005/050083 FR2005050083W WO2005078129A3 WO 2005078129 A3 WO2005078129 A3 WO 2005078129A3 FR 2005050083 W FR2005050083 W FR 2005050083W WO 2005078129 A3 WO2005078129 A3 WO 2005078129A3
Authority
WO
WIPO (PCT)
Prior art keywords
prognosis method
thrombosis diagnosis
amplicons
diagnosis
pair
Prior art date
Application number
PCT/FR2005/050083
Other languages
English (en)
Other versions
WO2005078129A2 (fr
Inventor
Aurelie Brion
Philippe Leissner
Cecile Berard
Original Assignee
Biomerieux Sa
Aurelie Brion
Philippe Leissner
Cecile Berard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux Sa, Aurelie Brion, Philippe Leissner, Cecile Berard filed Critical Biomerieux Sa
Priority to US10/585,923 priority Critical patent/US20070160996A1/en
Priority to JP2006552671A priority patent/JP2007521828A/ja
Priority to EP05726418A priority patent/EP1713939A2/fr
Publication of WO2005078129A2 publication Critical patent/WO2005078129A2/fr
Publication of WO2005078129A3 publication Critical patent/WO2005078129A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne un procédé in vitro pour le diagnostic/pronostic d'une thrombose comprenant les étapes suivantes : A - on extrait le matériel nucléique d'un échantillon biologique, B - on utilise au moins une paire d'amorces d'amplification pour obtenir des amplicons d'au moins une séquence cible du matériel nucléique C - on utilise au moins une sonde de détection pour détecter h présence desdits amplicons caractérisé en ce que, lors de l'étape B, ladite paire d'amorce comprend au moins une amorce d'amplification comprenant au moins 10 motifs nucléotidiques d'une séquence nucléotidique choisie parmi SEQ ID N' l ; 3 à 8, 15 et 16.
PCT/FR2005/050083 2004-02-12 2005-02-10 Procede pour le diagnostic/pronostic d’une thrombose WO2005078129A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/585,923 US20070160996A1 (en) 2004-02-12 2005-02-10 Thrombosis diagnosis/prognosis method
JP2006552671A JP2007521828A (ja) 2004-02-12 2005-02-10 血栓症の診断／予測方法
EP05726418A EP1713939A2 (fr) 2004-02-12 2005-02-10 Procede pour le diagnostic/pronostic d'une thrombose

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0450257 2004-02-12
FR0450257A FR2866349B1 (fr) 2004-02-12 2004-02-12 Procede de diagnostic/pronostic d'une thrombose

Publications (2)

Publication Number Publication Date
WO2005078129A2 WO2005078129A2 (fr) 2005-08-25
WO2005078129A3 true WO2005078129A3 (fr) 2005-11-10

Family

ID=34803479

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2005/050083 WO2005078129A2 (fr) 2004-02-12 2005-02-10 Procede pour le diagnostic/pronostic d’une thrombose

Country Status (5)

Country Link
US (1) US20070160996A1 (fr)
EP (1) EP1713939A2 (fr)
JP (1) JP2007521828A (fr)
FR (1) FR2866349B1 (fr)
WO (1) WO2005078129A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2499599C2 (ru) 2007-09-28 2013-11-27 Интрексон Корпорейшн Конструкции терапевтического переключения генов и биореакторы для экспрессии биотерапевтических молекул и их применение

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995021938A1 (fr) * 1994-02-14 1995-08-17 Rijks Universiteit Leiden Procede de depistage d'une anomalie genetique asssocie a la trombose et/ou a une mauvaise reponse anticoagulante a la proteine c activee
WO1997032040A2 (fr) * 1996-02-29 1997-09-04 Royal Infirmary Of Edinburgh Nhs Trust Detection d'une sequence d'acide nucleique
US6335184B1 (en) * 1993-07-23 2002-01-01 Bio-Rad Laboratories, Inc. Linked linear amplification of nucleic acids
WO2002020837A2 (fr) * 2000-09-08 2002-03-14 Pyrosequencing Ab Methode
WO2002046476A2 (fr) * 2000-10-27 2002-06-13 Abbott Laboratories Genotypage a l'aide de sondes partiellement complementaires
EP1398388A2 (fr) * 2002-08-09 2004-03-17 OGHAM GmbH Procédé pour la détermination du risque de thrombose en utilisant des matrices àADN

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4672040A (en) * 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4800159A (en) * 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5750338A (en) * 1986-10-23 1998-05-12 Amoco Corporation Target and background capture methods with amplification for affinity assays
US5234809A (en) * 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
CA2020958C (fr) * 1989-07-11 2005-01-11 Daniel L. Kacian Methodes d'amplification de sequences d'acide nucleique
US6043035A (en) * 1997-11-03 2000-03-28 Rijks University Leiden Method for determining a risk factor for thrombosis
US6140054A (en) * 1998-09-30 2000-10-31 University Of Utah Research Foundation Multiplex genotyping using fluorescent hybridization probes
US6936467B2 (en) * 2000-03-27 2005-08-30 University Of Delaware Targeted chromosomal genomic alterations with modified single stranded oligonucleotides
ES2267803T3 (es) * 2000-08-11 2007-03-16 University Of Utah Research Foundation Sondas de oligonucleotidos marcados individuales.

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335184B1 (en) * 1993-07-23 2002-01-01 Bio-Rad Laboratories, Inc. Linked linear amplification of nucleic acids
WO1995021938A1 (fr) * 1994-02-14 1995-08-17 Rijks Universiteit Leiden Procede de depistage d'une anomalie genetique asssocie a la trombose et/ou a une mauvaise reponse anticoagulante a la proteine c activee
WO1997032040A2 (fr) * 1996-02-29 1997-09-04 Royal Infirmary Of Edinburgh Nhs Trust Detection d'une sequence d'acide nucleique
WO2002020837A2 (fr) * 2000-09-08 2002-03-14 Pyrosequencing Ab Methode
WO2002046476A2 (fr) * 2000-10-27 2002-06-13 Abbott Laboratories Genotypage a l'aide de sondes partiellement complementaires
EP1398388A2 (fr) * 2002-08-09 2004-03-17 OGHAM GmbH Procédé pour la détermination du risque de thrombose en utilisant des matrices àADN

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
REITSMA P H ET AL: "USE OF THE DIRECT RNA AMPLIFICATION TECHNIQUE NASBA TO DETECT FACTOR V LEIDEN, A POINT MUTATION ASSOCIATED WITH APC RESISTANCE", BLOOD COAGULATION & FIBRINOLYSIS, RAPID COMMUNICATIONS, OXFORD,OXFORD, GB, vol. 7, no. 6, 1996, pages 659 - 663, XP000879262, ISSN: 0957-5235 *
SEVALL J S: "FACTOR V LEIDEN GENOTYPING USING REAL-TIME FLUORESCENT POLYMERASE CHAIN REACTION", MOLECULAR AND CELLULAR PROBES, ACADEMIC PRESS, LONDON, GB, vol. 14, no. 4, 2000, pages 249 - 253, XP009003590, ISSN: 0890-8508 *
UGOZZOLI L A ET AL: "Four-color multiplex 5' nuclease assay for the simultaneous detection of the factor V Leiden and the prothrombin G20210A mutations", MOLECULAR AND CELLULAR PROBES, ACADEMIC PRESS, LONDON, GB, vol. 18, no. 3, June 2004 (2004-06-01), pages 161 - 166, XP004506539, ISSN: 0890-8508 *

Also Published As

Publication number Publication date
US20070160996A1 (en) 2007-07-12
EP1713939A2 (fr) 2006-10-25
FR2866349B1 (fr) 2008-05-16
FR2866349A1 (fr) 2005-08-19
JP2007521828A (ja) 2007-08-09
WO2005078129A2 (fr) 2005-08-25

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