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WO2005056829A3 - Procede pour le diagnostic/pronostic du cancer du sein - Google Patents

Procede pour le diagnostic/pronostic du cancer du sein Download PDF

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Publication number
WO2005056829A3
WO2005056829A3 PCT/FR2004/050661 FR2004050661W WO2005056829A3 WO 2005056829 A3 WO2005056829 A3 WO 2005056829A3 FR 2004050661 W FR2004050661 W FR 2004050661W WO 2005056829 A3 WO2005056829 A3 WO 2005056829A3
Authority
WO
WIPO (PCT)
Prior art keywords
seq
breast cancer
prognosis
diagnosis
pair
Prior art date
Application number
PCT/FR2004/050661
Other languages
English (en)
Other versions
WO2005056829A2 (fr
Inventor
Thibaut Verjat
Original Assignee
Biomerieux Sa
Thibaut Verjat
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux Sa, Thibaut Verjat filed Critical Biomerieux Sa
Priority to EP04816515A priority Critical patent/EP1694868A2/fr
Priority to US10/579,986 priority patent/US20070134669A1/en
Publication of WO2005056829A2 publication Critical patent/WO2005056829A2/fr
Publication of WO2005056829A3 publication Critical patent/WO2005056829A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne un procédé pour le diagnostic/pronostic du cancer du sein comprenant les étapes suivantes : A - on extrait le matériel nucléique d'un échantillon biologique, B - on utilise au moins une paire d'amorces d'amplification pour obtenir des amplicons d'au moins une séquence cible du matériel nucléique, C - on utilise au moins une sonde de détection pour détecter la présence desdits amplicons caractérisé en ce que, lors de l'étape B, ladite paire d'amorce comprend au moins une amorce d'amplification comprenant au moins 10 motifs nucléotidiques d'une séquence nucléotidique choisie parmi SEQ ID N°1 à SEQ ID N°24 et/ou lors de l'étape C), ladite sonde de détection comprend au moins 10 motifs nucléotidiques d'une séquence nucléotidique choisie parmi SEQ ID N° l à SEQ ID N°20. L'invention concerne également des amorces d'amplification et des sondes d'hybridation qui peuvent être mises en œuvre dans ce procédé, ainsi qu'un kit de diagnostic/pronostic du cancer du sein.
PCT/FR2004/050661 2003-12-09 2004-12-07 Procede pour le diagnostic/pronostic du cancer du sein WO2005056829A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP04816515A EP1694868A2 (fr) 2003-12-09 2004-12-07 Procede pour le diagnostic/pronostic du cancer du sein
US10/579,986 US20070134669A1 (en) 2003-12-09 2004-12-07 Method for diagnosis/prognosis of breast cancer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0314364 2003-12-09
FR0314364A FR2863275B1 (fr) 2003-12-09 2003-12-09 Procede pour le diagnostic/pronostic du cancer du sein

Publications (2)

Publication Number Publication Date
WO2005056829A2 WO2005056829A2 (fr) 2005-06-23
WO2005056829A3 true WO2005056829A3 (fr) 2005-11-17

Family

ID=34586373

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2004/050661 WO2005056829A2 (fr) 2003-12-09 2004-12-07 Procede pour le diagnostic/pronostic du cancer du sein

Country Status (5)

Country Link
US (1) US20070134669A1 (fr)
EP (1) EP1694868A2 (fr)
CN (1) CN1890387A (fr)
FR (1) FR2863275B1 (fr)
WO (1) WO2005056829A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1750131B1 (fr) * 2005-08-01 2008-07-09 Sysmex Corporation Procédé de jugement de la caractéristique de la tumeur maligne
EP2155905A1 (fr) * 2007-05-31 2010-02-24 Dako Denmark A/S Procédés d'utilisation des changements du nombre de copies d'esr dans les traitements et les pronostics du cancer du sein
CN101868241A (zh) 2007-09-28 2010-10-20 英特瑞克斯顿股份有限公司 表达生物治疗分子的治疗基因开关构建物和生物反应器以及它们的应用
US20090203015A1 (en) * 2008-02-13 2009-08-13 Celera Corporation Multiplex assays for hormonal and growth factor receptors, and uses thereof
EP2568053B1 (fr) * 2008-05-12 2014-04-16 Genomic Health, Inc. Tests pour prédire une sensibilité de patients atteints de cancer à des options de traitement de chimiothérapie
EP2845911B1 (fr) * 2010-03-31 2016-05-18 Sividon Diagnostics GmbH Procédé de prédiction de la récurrence du cancer du sein sous traitement endocrinien
CN101921858B (zh) * 2010-08-23 2013-08-28 广州益善生物技术有限公司 乳腺癌预后相关基因mRNA表达水平检测液相芯片
CN102703591B (zh) * 2012-05-30 2014-04-23 北京艾迪康医学检验所有限公司 用于雌激素受体α基因内含子1 P vuII 和X baI 多态性焦磷酸检测的引物
CN112646864A (zh) * 2020-12-30 2021-04-13 杭州联川基因诊断技术有限公司 一种检测esr1基因表达的引物、探针、试剂盒和检测方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991002818A1 (fr) * 1989-08-23 1991-03-07 Cangene Corporation Procede d'amplification ameliore d'acides nucleiques
WO1999064631A1 (fr) * 1998-06-12 1999-12-16 Urocor, Inc. Biomarqueurs et cibles pour le diagnostic, le pronostic et le traitement relatifs au cancer de la prostate, du sein et de la vessie
WO2001042307A1 (fr) * 1999-12-07 2001-06-14 Sumitomo Chemical Company, Limited ERα MUTANTS ET SYSTEME DE TEST POUR TRANSACTIVATION
WO2002085298A2 (fr) * 2001-04-20 2002-10-31 Millennium Pharmaceutical, Inc. Nouveaux genes, compositions, kits et methodes d'identification, d'evaluation, de prevention et de therapie du cancer du sein
WO2003039443A2 (fr) * 2001-11-05 2003-05-15 Deutsches Krebsforschungszentrum Nouveaux marqueurs genetiques pour leucemies
WO2004005550A2 (fr) * 2002-07-04 2004-01-15 Fujisawa Pharmaceutical Co., Ltd. Procede de criblage d'antidiabetiques

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US4800159A (en) * 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
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CA2020958C (fr) * 1989-07-11 2005-01-11 Daniel L. Kacian Methodes d'amplification de sequences d'acide nucleique
US5545522A (en) * 1989-09-22 1996-08-13 Van Gelder; Russell N. Process for amplifying a target polynucleotide sequence using a single primer-promoter complex
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Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991002818A1 (fr) * 1989-08-23 1991-03-07 Cangene Corporation Procede d'amplification ameliore d'acides nucleiques
WO1999064631A1 (fr) * 1998-06-12 1999-12-16 Urocor, Inc. Biomarqueurs et cibles pour le diagnostic, le pronostic et le traitement relatifs au cancer de la prostate, du sein et de la vessie
WO2001042307A1 (fr) * 1999-12-07 2001-06-14 Sumitomo Chemical Company, Limited ERα MUTANTS ET SYSTEME DE TEST POUR TRANSACTIVATION
WO2002085298A2 (fr) * 2001-04-20 2002-10-31 Millennium Pharmaceutical, Inc. Nouveaux genes, compositions, kits et methodes d'identification, d'evaluation, de prevention et de therapie du cancer du sein
WO2003039443A2 (fr) * 2001-11-05 2003-05-15 Deutsches Krebsforschungszentrum Nouveaux marqueurs genetiques pour leucemies
WO2004005550A2 (fr) * 2002-07-04 2004-01-15 Fujisawa Pharmaceutical Co., Ltd. Procede de criblage d'antidiabetiques

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Also Published As

Publication number Publication date
FR2863275B1 (fr) 2007-08-10
FR2863275A1 (fr) 2005-06-10
EP1694868A2 (fr) 2006-08-30
WO2005056829A2 (fr) 2005-06-23
CN1890387A (zh) 2007-01-03
US20070134669A1 (en) 2007-06-14

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