WO2002000826A3 - Nouveau polypeptide, proteine humaine de methylation d'adn, et polynucleotide codant ce polypeptide - Google Patents
Nouveau polypeptide, proteine humaine de methylation d'adn, et polynucleotide codant ce polypeptide Download PDFInfo
- Publication number
- WO2002000826A3 WO2002000826A3 PCT/CN2001/000942 CN0100942W WO0200826A3 WO 2002000826 A3 WO2002000826 A3 WO 2002000826A3 CN 0100942 W CN0100942 W CN 0100942W WO 0200826 A3 WO0200826 A3 WO 0200826A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptide
- polynucleotide encoding
- dna methylation
- human dna
- discloses
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 230000007067 DNA methylation Effects 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 206010012559 Developmental delay Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000013020 embryo development Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne un nouveau polypeptide, une protéine humaine de méthylation d'ADN, et un polynucléotide codant ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment de tumeurs et de malformations lors du développement de l'embryon. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant la protéine humaine de méthylation d'ADN.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU89532/01A AU8953201A (en) | 2000-06-12 | 2001-06-11 | A novel polypeptide, a human dna methylation protein and the polynucleotide encoding the polypeptide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00116424.4 | 2000-06-12 | ||
| CN 00116424 CN1328143A (zh) | 2000-06-12 | 2000-06-12 | 一种新的多肽——人甲基化－dna－蛋白－半胱氨酸甲基转移酶13和编码这种多肽的多核苷酸 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2002000826A2 WO2002000826A2 (fr) | 2002-01-03 |
| WO2002000826A3 true WO2002000826A3 (fr) | 2002-04-04 |
Family
ID=4585828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000942 WO2002000826A2 (fr) | 2000-06-12 | 2001-06-11 | Nouveau polypeptide, proteine humaine de methylation d'adn, et polynucleotide codant ce polypeptide |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1328143A (fr) |
| AU (1) | AU8953201A (fr) |
| WO (1) | WO2002000826A2 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2910551T (pt) | 2003-04-11 | 2017-05-22 | Ptc Therapeutics Inc | Compostos do ácido 1,2,4-oxadiazole benzóico e a sua utilização para a supressão sem sentido e o tratamento de doenças |
| CN114916502B (zh) * | 2022-07-07 | 2023-06-16 | 电子科技大学 | 一种视网膜色素变性疾病模型的构建方法和应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4319875C1 (de) * | 1993-06-16 | 1994-08-04 | Kernforschungsz Karlsruhe | Plasmid zur Herstellung von sense- und antisense-RNA-Proben des menschlichen MGMT-Gens |
-
2000
- 2000-06-12 CN CN 00116424 patent/CN1328143A/zh active Pending
-
2001
- 2001-06-11 WO PCT/CN2001/000942 patent/WO2002000826A2/fr active Application Filing
- 2001-06-11 AU AU89532/01A patent/AU8953201A/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4319875C1 (de) * | 1993-06-16 | 1994-08-04 | Kernforschungsz Karlsruhe | Plasmid zur Herstellung von sense- und antisense-RNA-Proben des menschlichen MGMT-Gens |
Non-Patent Citations (2)
| Title |
|---|
| DATABASE GENBANK [online] 7 December 1999 (1999-12-07), RUMP A. ET AL., retrieved from GI:6531675 accession no. NCBI Database accession no. (AF205588.1) * |
| DATABASE PROTEIN [online] 14 April 2000 (2000-04-14), BROWN A. ET AL., retrieved from GI:7576272 accession no. NCBI Database accession no. (CAB87950.1) * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002000826A2 (fr) | 2002-01-03 |
| AU8953201A (en) | 2002-01-08 |
| CN1328143A (zh) | 2001-12-26 |
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