WO2002000827A3 - Nouveau polypeptide, proteine de methylation d'adn-cysteine methyl-transferase 10, et polynucleotide codant ce polypeptide - Google Patents
Nouveau polypeptide, proteine de methylation d'adn-cysteine methyl-transferase 10, et polynucleotide codant ce polypeptide Download PDFInfo
- Publication number
- WO2002000827A3 WO2002000827A3 PCT/CN2001/000943 CN0100943W WO0200827A3 WO 2002000827 A3 WO2002000827 A3 WO 2002000827A3 CN 0100943 W CN0100943 W CN 0100943W WO 0200827 A3 WO0200827 A3 WO 0200827A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptide
- dna
- polynucleotide encoding
- discloses
- novel
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 102000016397 Methyltransferase Human genes 0.000 title abstract 3
- 108060004795 Methyltransferase Proteins 0.000 title abstract 3
- 230000011987 methylation Effects 0.000 title abstract 3
- 238000007069 methylation reaction Methods 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 206010012559 Developmental delay Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000013020 embryo development Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne un nouveau polypeptide, une protéine de méthylation d'ADN-cystéine méthyl-transférase 10, et un polynucléotide codant ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment de tumeurs et d'anomalies apparaissant lors du développement de l'embryon. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant la protéine de méthylation d'ADN-cystéine méthyl-transférase 10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU93611/01A AU9361101A (en) | 2000-06-12 | 2001-06-11 | A novel polypeptide, a dna-cysteine methyltransferase methylation protein 10 andthe polynucleotide encoding the polypeptide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00116428.7 | 2000-06-12 | ||
| CN00116428A CN1328144A (zh) | 2000-06-12 | 2000-06-12 | 一种新的多肽——甲基化－dna－蛋白－半胱氨酸甲基转移酶10和编码这种多肽的多核苷酸 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2002000827A2 WO2002000827A2 (fr) | 2002-01-03 |
| WO2002000827A3 true WO2002000827A3 (fr) | 2002-05-02 |
Family
ID=4585832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000943 WO2002000827A2 (fr) | 2000-06-12 | 2001-06-11 | Nouveau polypeptide, proteine de methylation d'adn-cysteine methyl-transferase 10, et polynucleotide codant ce polypeptide |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1328144A (fr) |
| AU (1) | AU9361101A (fr) |
| WO (1) | WO2002000827A2 (fr) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994029454A1 (fr) * | 1993-06-16 | 1994-12-22 | Kernforschungszentrum Karlsruhe Gmbh | Plasmide de production de sondes a arn sens et anti-sens du gene mgmt humain |
| WO1998013487A1 (fr) * | 1996-09-27 | 1998-04-02 | Maxygen, Inc. | Procedes permettant l'optimisation d'une therapie genique grace a un rearrangement et une selection recursifs de sequences |
-
2000
- 2000-06-12 CN CN00116428A patent/CN1328144A/zh active Pending
-
2001
- 2001-06-11 WO PCT/CN2001/000943 patent/WO2002000827A2/fr active Application Filing
- 2001-06-11 AU AU93611/01A patent/AU9361101A/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994029454A1 (fr) * | 1993-06-16 | 1994-12-22 | Kernforschungszentrum Karlsruhe Gmbh | Plasmide de production de sondes a arn sens et anti-sens du gene mgmt humain |
| WO1998013487A1 (fr) * | 1996-09-27 | 1998-04-02 | Maxygen, Inc. | Procedes permettant l'optimisation d'une therapie genique grace a un rearrangement et une selection recursifs de sequences |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002000827A2 (fr) | 2002-01-03 |
| CN1328144A (zh) | 2001-12-26 |
| AU9361101A (en) | 2002-01-08 |
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