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WO2002053716A3 - Regulation de l'ornithine decarboxylase humaine - Google Patents

Regulation de l'ornithine decarboxylase humaine Download PDF

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Publication number
WO2002053716A3
WO2002053716A3 PCT/EP2001/015323 EP0115323W WO02053716A3 WO 2002053716 A3 WO2002053716 A3 WO 2002053716A3 EP 0115323 W EP0115323 W EP 0115323W WO 02053716 A3 WO02053716 A3 WO 02053716A3
Authority
WO
WIPO (PCT)
Prior art keywords
ornithine decarboxylase
human ornithine
regulation
reagents
human
Prior art date
Application number
PCT/EP2001/015323
Other languages
English (en)
Other versions
WO2002053716A2 (fr
Inventor
Timothy J Smith
Original Assignee
Bayer Ag
Timothy J Smith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Timothy J Smith filed Critical Bayer Ag
Priority to AU2002238483A priority Critical patent/AU2002238483A1/en
Publication of WO2002053716A2 publication Critical patent/WO2002053716A2/fr
Publication of WO2002053716A3 publication Critical patent/WO2002053716A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01017—Ornithine decarboxylase (4.1.1.17)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Les réactifs régulant l'ornithine décarboxylase humaine et les réactifs se liant aux produits géniques de l'ornithine décarboxylase humaine peuvent jouer un rôle important dans la prévention, l'amélioration ou la correction de dysfonctionnements ou de maladies, y compris mais de façon non limitative le cancer, le diabète et les troubles des systèmes nerveux périphérique et central.
PCT/EP2001/015323 2001-01-03 2001-12-27 Regulation de l'ornithine decarboxylase humaine WO2002053716A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002238483A AU2002238483A1 (en) 2001-01-03 2001-12-27 Regulation of human ornithine decarboxylase

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25921101P 2001-01-03 2001-01-03
US60/259,211 2001-01-03

Publications (2)

Publication Number Publication Date
WO2002053716A2 WO2002053716A2 (fr) 2002-07-11
WO2002053716A3 true WO2002053716A3 (fr) 2003-02-27

Family

ID=22984001

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/015323 WO2002053716A2 (fr) 2001-01-03 2001-12-27 Regulation de l'ornithine decarboxylase humaine

Country Status (2)

Country Link
AU (1) AU2002238483A1 (fr)
WO (1) WO2002053716A2 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0542287A2 (fr) * 1991-11-14 1993-05-19 Idemitsu Kosan Company Limited Anticorps contre le décarboxylase d'ornithine humain
WO2000061624A1 (fr) * 1999-04-09 2000-10-19 Human Genome Sciences, Inc. 48 proteines secretees humaines
WO2001053312A1 (fr) * 1999-12-23 2001-07-26 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides
WO2002000840A2 (fr) * 2000-06-23 2002-01-03 Incyte Genomics, Inc. Lyases humaines

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0542287A2 (fr) * 1991-11-14 1993-05-19 Idemitsu Kosan Company Limited Anticorps contre le décarboxylase d'ornithine humain
WO2000061624A1 (fr) * 1999-04-09 2000-10-19 Human Genome Sciences, Inc. 48 proteines secretees humaines
WO2001053312A1 (fr) * 1999-12-23 2001-07-26 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides
WO2002000840A2 (fr) * 2000-06-23 2002-01-03 Incyte Genomics, Inc. Lyases humaines

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
AUVINEN MERJA ET AL: "Ornithine decarboxylase activity is critical for cell transformation.", NATURE (LONDON), vol. 360, no. 6402, 1992, pages 355 - 358, XP001093669, ISSN: 0028-0836 *
CAO YING ET AL: "Tissue-specific expression of an ornithine decarboxylase paralogue, XODC2, in Xenopus laevis.", MECHANISMS OF DEVELOPMENT, vol. 102, no. 1-2, April 2001 (2001-04-01), pages 243 - 246, XP002212079, ISSN: 0925-4773 *
CAO YING ET AL: "Tissue-specific expression of an ornithine decarboxylase paralogue, XODC2, in Xenopus laevis.", MECHANISMS OF DEVELOPMENT, vol. 102, no. 1-2, April 2001 (2001-04-01), pages 243 - 246, XP002212079, ISSN: 0925-4773, DOI: doi:10.1016/S0925-4773(01)00295-7 *
DATABASE EMBL [online] "wb09f08.x1 NCI_CGAP_GC6 Homo sapiens cDNA clone IMAGE:2305191 3' similar to SW:DCOR_MUSPA P27119 ORNITHINE DECARBOXYLASE ;, mRNA sequence.", XP002212042, Database accession no. AI632488 *
DATABASE EMBL [online] 1 October 2000 (2000-10-01), "Ornithine decarboxylase-2", XP002212044, Database accession no. Q9I8S4 *
DATABASE EMBL [online] 25 January 2000 (2000-01-25), "Xenopus laevis ornithine decarboxylase-2 mRNA, complete cds", XP002212043, Database accession no. AF217544 *
DATABASE GENESEQ [online] 22 October 2001 (2001-10-22), "human polynucleotide SEQ ID NO 1188", XP002212045, Database accession no. AAI58985 *
DATABASE GENESEQ [online] 22 October 2001 (2001-10-22), "human polypeptide SEQ ID NO: 2974", XP002212046, Database accession no. AAM39829 *
HICKOK N J ET AL: "Complete amino acid sequence of human ornithine decarboxylase deduced from complementary DNA.", DNA (MARY ANN LIEBERT, INC.) UNITED STATES JUN 1987, vol. 6, no. 3, June 1987 (1987-06-01), pages 179 - 187, XP001097304, ISSN: 0198-0238 *
PITKANEN LAURA T ET AL: "Expression of a novel human ornithine decarboxylase-like protein in the central nervous system and testes.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 287, no. 5, 12 October 2001 (2001-10-12), pages 1051 - 1057, XP002212041, ISSN: 0006-291X *

Also Published As

Publication number Publication date
AU2002238483A1 (en) 2002-07-16
WO2002053716A2 (fr) 2002-07-11

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