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WO2001087907A3 - Haplotypes of the osm gene - Google Patents

Haplotypes of the osm gene Download PDF

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Publication number
WO2001087907A3
WO2001087907A3 PCT/US2001/016157 US0116157W WO0187907A3 WO 2001087907 A3 WO2001087907 A3 WO 2001087907A3 US 0116157 W US0116157 W US 0116157W WO 0187907 A3 WO0187907 A3 WO 0187907A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
osm
gene
disclosed
osm gene
Prior art date
Application number
PCT/US2001/016157
Other languages
French (fr)
Other versions
WO2001087907A2 (en
Inventor
Amy E Duda
Amir Kazemi
Beena Koshy
Original Assignee
Genaissance Pharmaceuticals
Amy E Duda
Amir Kazemi
Beena Koshy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Amy E Duda, Amir Kazemi, Beena Koshy filed Critical Genaissance Pharmaceuticals
Priority to AU2001264681A priority Critical patent/AU2001264681A1/en
Publication of WO2001087907A2 publication Critical patent/WO2001087907A2/en
Publication of WO2001087907A3 publication Critical patent/WO2001087907A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

Novel genetic variants of the Oncostatin M (OSM) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the OSM gene. Compositions and methods for haplotyping and/or genotyping the OSM gene in an individual are also disclosed. Polynucleotides defined by the sequence the haplotypes disclosed herein are also described.
PCT/US2001/016157 2000-05-17 2001-05-17 Haplotypes of the osm gene WO2001087907A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001264681A AU2001264681A1 (en) 2001-05-17 2001-05-17 Haplotypes of the osm gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20486800P 2000-05-17 2000-05-17
US60/204,868 2000-05-17

Publications (2)

Publication Number Publication Date
WO2001087907A2 WO2001087907A2 (en) 2001-11-22
WO2001087907A3 true WO2001087907A3 (en) 2002-04-11

Family

ID=22759790

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016157 WO2001087907A2 (en) 2000-05-17 2001-05-17 Haplotypes of the osm gene

Country Status (1)

Country Link
WO (1) WO2001087907A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1327639A1 (en) * 2002-01-15 2003-07-16 Bayer Ag Prediction of cardiovascular disease by genetic polymorphisms in cardiovascular associated genes

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5521301A (en) * 1988-12-12 1996-05-28 City Of Hope Genotyping of multiple allele systems
US5851762A (en) * 1990-07-11 1998-12-22 Gene Type Ag Genomic mapping method by direct haplotyping using intron sequence analysis
US5874536A (en) * 1989-12-08 1999-02-23 Bristol-Myers Squibb Company Proteins with Oncostatin M activity and process for their preparation
WO1999041364A2 (en) * 1998-02-13 1999-08-19 The Wistar Institute Compositions and methods for wound healing

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5521301A (en) * 1988-12-12 1996-05-28 City Of Hope Genotyping of multiple allele systems
US5874536A (en) * 1989-12-08 1999-02-23 Bristol-Myers Squibb Company Proteins with Oncostatin M activity and process for their preparation
US5851762A (en) * 1990-07-11 1998-12-22 Gene Type Ag Genomic mapping method by direct haplotyping using intron sequence analysis
WO1999041364A2 (en) * 1998-02-13 1999-08-19 The Wistar Institute Compositions and methods for wound healing

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HAI-QING ET AL.: "Molecular cloning and expression of oncostatin M", CHINESE BIOCHEMICAL JOURNAL, vol. 13, no. 3, June 1997 (1997-06-01), pages 259 - 263, XP002905194 *
MA ET AL.: "Cloning and characterization of human oncostatin M promoter", NUCLEIC ACIDS RESEARCH, vol. 27, no. 23, 1999, pages 4649 - 4657, XP002905193 *

Also Published As

Publication number Publication date
WO2001087907A2 (en) 2001-11-22

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