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WO2002042320A3 - Haplotypes of the gsr gene - Google Patents

Haplotypes of the gsr gene Download PDF

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Publication number
WO2002042320A3
WO2002042320A3 PCT/US2001/046473 US0146473W WO0242320A3 WO 2002042320 A3 WO2002042320 A3 WO 2002042320A3 US 0146473 W US0146473 W US 0146473W WO 0242320 A3 WO0242320 A3 WO 0242320A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
gsr
gene
disclosed
gsr gene
Prior art date
Application number
PCT/US2001/046473
Other languages
French (fr)
Other versions
WO2002042320A2 (en
Inventor
Karyn M Bieglecki
Angela Sanchis
Elizabeth Ann Sausker
Xiao Sun
Original Assignee
Genaissance Pharmaceuticals
Karyn M Bieglecki
Angela Sanchis
Elizabeth Ann Sausker
Xiao Sun
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Karyn M Bieglecki, Angela Sanchis, Elizabeth Ann Sausker, Xiao Sun filed Critical Genaissance Pharmaceuticals
Priority to AU2002239511A priority Critical patent/AU2002239511A1/en
Publication of WO2002042320A2 publication Critical patent/WO2002042320A2/en
Publication of WO2002042320A3 publication Critical patent/WO2002042320A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Novel genetic variants of the Glutathione Reductase (GSR) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the GSR gene. Compositions and methods for haplotyping and/or genotyping the GSR gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
PCT/US2001/046473 2000-11-10 2001-11-13 Haplotypes of the gsr gene WO2002042320A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002239511A AU2002239511A1 (en) 2000-11-10 2001-11-13 Haplotypes of the gsr gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24720200P 2000-11-10 2000-11-10
US60/247,202 2000-11-10

Publications (2)

Publication Number Publication Date
WO2002042320A2 WO2002042320A2 (en) 2002-05-30
WO2002042320A3 true WO2002042320A3 (en) 2003-12-31

Family

ID=22934014

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046473 WO2002042320A2 (en) 2000-11-10 2001-11-13 Haplotypes of the gsr gene

Country Status (2)

Country Link
AU (1) AU2002239511A1 (en)
WO (1) WO2002042320A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2245169A2 (en) * 2008-02-14 2010-11-03 Pioneer Hi-Bred International Inc. Plant genomic dna flanking spt event and methods for identifying spt event

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KELNER M.J. ET AL: "Structural Organization of the Human Glutathione Reductase Gene: Determination of Correct cDNA Sequence and Identification of a Mitochondrial Leader Sequence", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 269, 2000, pages 366 - 368, XP002959405 *

Also Published As

Publication number Publication date
WO2002042320A2 (en) 2002-05-30
AU2002239511A1 (en) 2002-06-03

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