WO2001083675A3 - Nouveau polypeptide, serine hydrolase humaine atp-dependante 10.2, et polynucleotide codant pour ce polypeptide - Google Patents
Nouveau polypeptide, serine hydrolase humaine atp-dependante 10.2, et polynucleotide codant pour ce polypeptide Download PDFInfo
- Publication number
- WO2001083675A3 WO2001083675A3 PCT/CN2001/000576 CN0100576W WO0183675A3 WO 2001083675 A3 WO2001083675 A3 WO 2001083675A3 CN 0100576 W CN0100576 W CN 0100576W WO 0183675 A3 WO0183675 A3 WO 0183675A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptide
- atp
- polynucleotide encoding
- dependent human
- discloses
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 title abstract 3
- 230000001419 dependent effect Effects 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne un nouveau polypeptide, une sérine hydrolase humaine ATP-dépendante 10.2, et un polynucléotide codant pour ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment des tumeurs malignes, de l'hémopathie, de l'infection par VIH, de maladies immunitaires et de diverses inflammations. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant pour la sérine hydrolase humaine ATP-dépendante 10.2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU68897/01A AU6889701A (en) | 2000-04-27 | 2001-04-23 | A novel polypeptide, a atp-dependent human hydrolase serine 10.2 and the polynucleotide encoding the polypeptide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00115490 CN1320703A (zh) | 2000-04-27 | 2000-04-27 | 一种新的多肽——人atp依赖的丝氨酸蛋白水解酶10.2和编码这种多肽的多核苷酸 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001083675A2 WO2001083675A2 (fr) | 2001-11-08 |
| WO2001083675A3 true WO2001083675A3 (fr) | 2002-04-25 |
Family
ID=4584936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000576 WO2001083675A2 (fr) | 2000-04-27 | 2001-04-23 | Nouveau polypeptide, serine hydrolase humaine atp-dependante 10.2, et polynucleotide codant pour ce polypeptide |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1320703A (fr) |
| AU (1) | AU6889701A (fr) |
| WO (1) | WO2001083675A2 (fr) |
-
2000
- 2000-04-27 CN CN 00115490 patent/CN1320703A/zh active Pending
-
2001
- 2001-04-23 WO PCT/CN2001/000576 patent/WO2001083675A2/fr active Application Filing
- 2001-04-23 AU AU68897/01A patent/AU6889701A/en not_active Abandoned
Non-Patent Citations (2)
| Title |
|---|
| DATABASE PROTEIN [online] 22 June 1999 (1999-06-22), ALM R.A. ET AL.,, accession no. NCBI Database accession no. (H71895) * |
| DATABASE PROTEIN [online] 8 October 1999 (1999-10-08), ALM R.A. ET AL., accession no. NCBI Database accession no. (F71826) * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1320703A (zh) | 2001-11-07 |
| AU6889701A (en) | 2001-11-12 |
| WO2001083675A2 (fr) | 2001-11-08 |
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