WO2001081538A3 - Nouveau polypeptide, connexine humaine 9, et polynucleotide codant pour ce polypeptide - Google Patents
Nouveau polypeptide, connexine humaine 9, et polynucleotide codant pour ce polypeptide Download PDFInfo
- Publication number
- WO2001081538A3 WO2001081538A3 PCT/CN2001/000608 CN0100608W WO0181538A3 WO 2001081538 A3 WO2001081538 A3 WO 2001081538A3 CN 0100608 W CN0100608 W CN 0100608W WO 0181538 A3 WO0181538 A3 WO 0181538A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptide
- polynucleotide encoding
- discloses
- human connexin
- novel
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 102000010970 Connexin Human genes 0.000 title abstract 3
- 108050001175 Connexin Proteins 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
L'invention concerne un nouveau polypeptide, une connexine humaine 9, et un polynucléotide codant pour ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment des tumeurs malignes, de l'hémopathie, de l'infection par VIH, de maladies immunitaires et de diverses inflammations. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant pour la connexine humaine 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU75632/01A AU7563201A (en) | 2000-04-27 | 2001-04-23 | A novel polypeptide, a human connexin 9 and the polynucleotide encoding the polypeptide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00115456A CN1320619A (zh) | 2000-04-27 | 2000-04-27 | 一种新的多肽——人间隙连接蛋白9和编码这种多肽的多核苷酸 |
| CN00115456.7 | 2000-04-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001081538A2 WO2001081538A2 (fr) | 2001-11-01 |
| WO2001081538A3 true WO2001081538A3 (fr) | 2002-04-25 |
Family
ID=4584902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000608 WO2001081538A2 (fr) | 2000-04-27 | 2001-04-23 | Nouveau polypeptide, connexine humaine 9, et polynucleotide codant pour ce polypeptide |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1320619A (fr) |
| AU (1) | AU7563201A (fr) |
| WO (1) | WO2001081538A2 (fr) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4420791C1 (de) * | 1994-06-15 | 1995-05-18 | Hinrich Dr Luehring | Verfahren zur Expression von genetisch modifizierten Molekülen und dafür geeignete Wirtszellen |
| WO2000012711A2 (fr) * | 1998-09-02 | 2000-03-09 | Incyte Pharmaceuticals, Inc. | Proteines membranaires de canal humaines |
-
2000
- 2000-04-27 CN CN00115456A patent/CN1320619A/zh active Pending
-
2001
- 2001-04-23 AU AU75632/01A patent/AU7563201A/en not_active Abandoned
- 2001-04-23 WO PCT/CN2001/000608 patent/WO2001081538A2/fr active Application Filing
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4420791C1 (de) * | 1994-06-15 | 1995-05-18 | Hinrich Dr Luehring | Verfahren zur Expression von genetisch modifizierten Molekülen und dafür geeignete Wirtszellen |
| WO2000012711A2 (fr) * | 1998-09-02 | 2000-03-09 | Incyte Pharmaceuticals, Inc. | Proteines membranaires de canal humaines |
Non-Patent Citations (2)
| Title |
|---|
| CLARK S.W. AND MEYER D.I.: "Centractin is in actin homologue associated with the centrosome", NATURE, vol. 359, no. 6392, 1992, pages 246 - 250 * |
| FAULKNER N.E. ET AL.: "Localization of motor-related proteins and associated complexes to active, but not inactive, centromeres", HUM. MOL. GENET., vol. 7, no. 4, 1998, pages 671 - 677 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU7563201A (en) | 2001-11-07 |
| CN1320619A (zh) | 2001-11-07 |
| WO2001081538A2 (fr) | 2001-11-01 |
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