WO2001075062A3 - Nouveau polypeptide, hydrogenase humaine 10, et polynucleotide codant pour ce polypeptide - Google Patents
Nouveau polypeptide, hydrogenase humaine 10, et polynucleotide codant pour ce polypeptide Download PDFInfo
- Publication number
- WO2001075062A3 WO2001075062A3 PCT/CN2001/000535 CN0100535W WO0175062A3 WO 2001075062 A3 WO2001075062 A3 WO 2001075062A3 CN 0100535 W CN0100535 W CN 0100535W WO 0175062 A3 WO0175062 A3 WO 0175062A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptide
- hydrogenase
- human
- polynucleotide encoding
- discloses
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 108010020056 Hydrogenase Proteins 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 206010012559 Developmental delay Diseases 0.000 abstract 1
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0067—Oxidoreductases (1.) acting on hydrogen as donor (1.12)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
L'invention concerne un nouveau polypeptide, une hydrogénase humaine 10, et un polynucléotide codant pour ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment des tumeurs malignes, de l'hémopathie, des troubles du développement, de l'infection par VIH, de maladies immunitaires et de diverses inflammations. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant pour l'hydrogénase humaine 10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU60037/01A AU6003701A (en) | 2000-03-29 | 2001-03-26 | A novel polypeptide, human hydrogenase 10 and the polynucleotide encoding the polypeptide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00115254A CN1315528A (zh) | 2000-03-29 | 2000-03-29 | 一种新的多肽——人氢化酶10和编码这种多肽的多核苷酸 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001075062A2 WO2001075062A2 (fr) | 2001-10-11 |
| WO2001075062A3 true WO2001075062A3 (fr) | 2002-01-24 |
Family
ID=4584722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000535 WO2001075062A2 (fr) | 2000-03-29 | 2001-03-26 | Nouveau polypeptide, hydrogenase humaine 10, et polynucleotide codant pour ce polypeptide |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1315528A (fr) |
| AU (1) | AU6003701A (fr) |
| WO (1) | WO2001075062A2 (fr) |
-
2000
- 2000-03-29 CN CN00115254A patent/CN1315528A/zh active Pending
-
2001
- 2001-03-26 AU AU60037/01A patent/AU6003701A/en not_active Abandoned
- 2001-03-26 WO PCT/CN2001/000535 patent/WO2001075062A2/fr active Application Filing
Non-Patent Citations (2)
| Title |
|---|
| BLATTNER F.R. ET AL.: "The complete genome sequence of escherichia coli K-12", SCIENCE, vol. 277, no. 5331, 1997, pages 1453 - 1474 * |
| KAWASHIMA T. ET AL.: "Determination of the complkete genomic DNA sequence of thermoplasma volvanium GSS1", PROC. JPN. ACAD., vol. 75, 1999, pages 213 - 218 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001075062A2 (fr) | 2001-10-11 |
| CN1315528A (zh) | 2001-10-03 |
| AU6003701A (en) | 2001-10-15 |
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