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WO1999032622A3 - Semaphorine zsmf-3 - Google Patents

Semaphorine zsmf-3 Download PDF

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Publication number
WO1999032622A3
WO1999032622A3 PCT/US1998/026793 US9826793W WO9932622A3 WO 1999032622 A3 WO1999032622 A3 WO 1999032622A3 US 9826793 W US9826793 W US 9826793W WO 9932622 A3 WO9932622 A3 WO 9932622A3
Authority
WO
WIPO (PCT)
Prior art keywords
semaphorin
polypeptides
zsmf
methods
truncated
Prior art date
Application number
PCT/US1998/026793
Other languages
English (en)
Other versions
WO1999032622A2 (fr
Inventor
James L Holloway
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU20002/99A priority Critical patent/AU2000299A/en
Publication of WO1999032622A2 publication Critical patent/WO1999032622A2/fr
Publication of WO1999032622A3 publication Critical patent/WO1999032622A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Cette invention se rapporte à des polypeptides de sémaphorine, à des polynucléotides codant ces polypeptides et à des compositions et des procédés associés. Ces polypeptides contiennent une sémaphorine tronquée soluble qui est fortement exprimée dans les tissus de l'estomac. Ces polypeptides peuvent servir dans des procédés pour détecter des récepteurs qui induisent une excroissance des neurites et ils peuvent également avoir une valeur immunologique.
PCT/US1998/026793 1997-12-19 1998-12-16 Semaphorine zsmf-3 WO1999032622A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU20002/99A AU2000299A (en) 1997-12-19 1998-12-16 Semaphorin zsmf-3

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99449497A 1997-12-19 1997-12-19
US08/994,494 1997-12-19

Publications (2)

Publication Number Publication Date
WO1999032622A2 WO1999032622A2 (fr) 1999-07-01
WO1999032622A3 true WO1999032622A3 (fr) 1999-09-10

Family

ID=25540710

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/026793 WO1999032622A2 (fr) 1997-12-19 1998-12-16 Semaphorine zsmf-3

Country Status (2)

Country Link
AU (1) AU2000299A (fr)
WO (1) WO1999032622A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2352495A1 (fr) 1998-11-26 2000-06-02 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Semaphorine humaine 6a-1(sema6a-1), gene implique dans des mecanismes de developpement et de regeneration neuronaux pendant l'apoptose, et son utilisation en tant que cible potentielle de medicaments
WO2001017559A1 (fr) * 1999-09-08 2001-03-15 Immunex Corporation Modulation par semaphorines de la migration des cellules immunitaires
WO2001040278A2 (fr) * 1999-12-06 2001-06-07 Zymogenetics, Inc. Semaphorine humaine zsmf-16
CA2395736A1 (fr) * 1999-12-23 2001-07-26 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides associes
WO2001053466A1 (fr) * 1999-12-23 2001-07-26 Hyseq, Inc. Procedes et substances relatifs a des polypeptides de type semaphorine et a des polynucleotides
US6635742B1 (en) 2000-01-25 2003-10-21 Nuvelo, Inc. Antibodies specific for semaphorin-like polypeptides

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027205A2 (fr) * 1996-12-18 1998-06-25 Genetics Institute, Inc. Proteines secretees et polynucleotides codant pour lesdites proteines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027205A2 (fr) * 1996-12-18 1998-06-25 Genetics Institute, Inc. Proteines secretees et polynucleotides codant pour lesdites proteines

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KOLODKIN ET AL: "Semaphorins: Mediators of repulsive growth cone guidance", TRENDS IN CELL BIOLOGY, vol. 6, no. 1, 1 January 1996 (1996-01-01), pages 15 - 22, XP002084499, ISSN: 0962-8924 *
ZHOU L ET AL: "Cloning and expression of a novel murine semaphorin with structural similarity to insect semaphorin I", MOLECULAR AND CELLULAR NEUROSCIENCES., vol. 9, no. 1, January 1997 (1997-01-01), SAN DIEGO, US, pages 26 - 41, XP002109255, ISSN: 1044-7431 *

Also Published As

Publication number Publication date
WO1999032622A2 (fr) 1999-07-01
AU2000299A (en) 1999-07-12

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