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WO1999045114A3 - Semaphorine humaine zsmf-7 - Google Patents

Semaphorine humaine zsmf-7 Download PDF

Info

Publication number
WO1999045114A3
WO1999045114A3 PCT/US1999/004758 US9904758W WO9945114A3 WO 1999045114 A3 WO1999045114 A3 WO 1999045114A3 US 9904758 W US9904758 W US 9904758W WO 9945114 A3 WO9945114 A3 WO 9945114A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
zsmf
human semaphorin
methods
semaphorin
Prior art date
Application number
PCT/US1999/004758
Other languages
English (en)
Other versions
WO1999045114A2 (fr
Inventor
James L Holloway
Catherine E Lofton-Day
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU29827/99A priority Critical patent/AU2982799A/en
Publication of WO1999045114A2 publication Critical patent/WO1999045114A2/fr
Publication of WO1999045114A3 publication Critical patent/WO1999045114A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Cette invention a trait à des polypeptides de sémaphorine, à des polynucléotides codant ces polypeptides ainsi qu'à des compositions apparentées et à des techniques connexes. Les polypeptides sont exprimés dans les tissus neuronaux et lymphatiques. Il est possible d'utiliser ces polypeptides dans le cadre de techniques de détection de récepteurs ayant une incidence sur la croissance des axones et des dendrites et/ou modulant la prolifération et/ou la différenciation et la réaction immunitaire.
PCT/US1999/004758 1998-03-03 1999-03-03 Semaphorine humaine zsmf-7 WO1999045114A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU29827/99A AU2982799A (en) 1998-03-03 1999-03-03 Human semaphorin zsmf-7

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7661198P 1998-03-03 1998-03-03
US60/076,611 1998-03-03

Publications (2)

Publication Number Publication Date
WO1999045114A2 WO1999045114A2 (fr) 1999-09-10
WO1999045114A3 true WO1999045114A3 (fr) 1999-11-04

Family

ID=22133130

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/004758 WO1999045114A2 (fr) 1998-03-03 1999-03-03 Semaphorine humaine zsmf-7

Country Status (2)

Country Link
AU (1) AU2982799A (fr)
WO (1) WO1999045114A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892047A3 (fr) 1997-07-09 2000-03-08 Hoechst Marion Roussel Deutschland GmbH Semaphorine L humaine et murine
WO1999058676A2 (fr) * 1998-05-14 1999-11-18 Immunex Corporation Polypeptides de semaphorine
AU770157B2 (en) * 1999-09-08 2004-02-12 Immunex Corporation Use of semaphorin for modulation of cellular efflux
WO2001032707A1 (fr) * 1999-11-02 2001-05-10 Zymogenetics, Inc. Semaphorine humaine
AU2669501A (en) * 1999-11-30 2001-06-12 Smithkline Beecham Plc New use
AU2065501A (en) * 1999-12-06 2001-06-12 Zymogenetics Inc. Human semaphorin zsmf-16
AU2001245871B2 (en) 2000-03-20 2006-06-01 Lexicon Pharmaceuticals, Inc. Novel human secreted proteins and polynucleotides encoding the same
CN1329060A (zh) * 2000-06-19 2002-01-02 上海博德基因开发有限公司 一种新的多肽——人semaphorin蛋白9和编码这种多肽的多核苷酸
AUPS271902A0 (en) * 2002-05-31 2002-06-20 Griffith University Gene expression and multiple sclerosis
US20070010433A1 (en) * 2002-07-11 2007-01-11 Sema Aps Use of compounds capable of inhibiting the proteolytic processing of semaphorins for prevention, treatment, diagnosis and prognosis of an invasive disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892047A2 (fr) * 1997-07-09 1999-01-20 Hoechst Marion Roussel Deutschland GmbH Semaphorine L humaine et murine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892047A2 (fr) * 1997-07-09 1999-01-20 Hoechst Marion Roussel Deutschland GmbH Semaphorine L humaine et murine

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ENSSER A ET AL: "Alcephaline herpesvirus type 1 has a semaphorin-like gene", JOURNAL OF GENERAL VIROLOGY., vol. 76, 1995, SOCIETY FOR GENERAL MICROBIOLOGY, READING., GB, pages 1063 - 1067, XP002113888, ISSN: 0022-1317 *
LANGE C ET AL: "New eukaryotic semaphorins with close homology to semaphorins of viruses", GENOMICS., vol. 51, 1 August 1998 (1998-08-01), SAN DIEGO., US, pages 340 - 350, XP002113887, ISSN: 0888-7543 *
XU X ET AL: "Human semaphorin K1 is glycosylphosphatidylinositol-linked and defines a new subfamily of viral-related semaphorins", JOURNAL OF BIOLOGICAL CHEMISTRY., vol. 273, no. 35, 28 August 1998 (1998-08-28), AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD., US, pages 22428 - 22434, XP002113886, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
WO1999045114A2 (fr) 1999-09-10
AU2982799A (en) 1999-09-20

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