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WO1999032622A3 - Semaphorin zsmf-3 - Google Patents

Semaphorin zsmf-3 Download PDF

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Publication number
WO1999032622A3
WO1999032622A3 PCT/US1998/026793 US9826793W WO9932622A3 WO 1999032622 A3 WO1999032622 A3 WO 1999032622A3 US 9826793 W US9826793 W US 9826793W WO 9932622 A3 WO9932622 A3 WO 9932622A3
Authority
WO
WIPO (PCT)
Prior art keywords
semaphorin
polypeptides
zsmf
methods
truncated
Prior art date
Application number
PCT/US1998/026793
Other languages
French (fr)
Other versions
WO1999032622A2 (en
Inventor
James L Holloway
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU20002/99A priority Critical patent/AU2000299A/en
Publication of WO1999032622A2 publication Critical patent/WO1999032622A2/en
Publication of WO1999032622A3 publication Critical patent/WO1999032622A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Semaphorin polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides include a soluble, truncated semaphorin that is highly expressed in stomach tissue. The polypeptides may be used within methods for detecting receptors that mediate neurite outgrowth, and may also have immunological value.
PCT/US1998/026793 1997-12-19 1998-12-16 Semaphorin zsmf-3 WO1999032622A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU20002/99A AU2000299A (en) 1997-12-19 1998-12-16 Semaphorin zsmf-3

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99449497A 1997-12-19 1997-12-19
US08/994,494 1997-12-19

Publications (2)

Publication Number Publication Date
WO1999032622A2 WO1999032622A2 (en) 1999-07-01
WO1999032622A3 true WO1999032622A3 (en) 1999-09-10

Family

ID=25540710

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/026793 WO1999032622A2 (en) 1997-12-19 1998-12-16 Semaphorin zsmf-3

Country Status (2)

Country Link
AU (1) AU2000299A (en)
WO (1) WO1999032622A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1135488A1 (en) 1998-11-26 2001-09-26 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Human semaphorin 6a-1 (sema6a-1), a gene involved in neuronal development and regeneration mechanisms during apoptosis, and its use as a potential drug target
AU7121900A (en) * 1999-09-08 2001-04-10 Immunex Corporation Semaphorin modulation of immune cell migration
AU2065501A (en) * 1999-12-06 2001-06-12 Zymogenetics Inc. Human semaphorin zsmf-16
WO2001053466A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Methods and materials relating to semaphorin-like polypeptides and polynucleotides
CA2395736A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Novel nucleic acids and polypeptides
US6635742B1 (en) 2000-01-25 2003-10-21 Nuvelo, Inc. Antibodies specific for semaphorin-like polypeptides

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027205A2 (en) * 1996-12-18 1998-06-25 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027205A2 (en) * 1996-12-18 1998-06-25 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KOLODKIN ET AL: "Semaphorins: Mediators of repulsive growth cone guidance", TRENDS IN CELL BIOLOGY, vol. 6, no. 1, 1 January 1996 (1996-01-01), pages 15 - 22, XP002084499, ISSN: 0962-8924 *
ZHOU L ET AL: "Cloning and expression of a novel murine semaphorin with structural similarity to insect semaphorin I", MOLECULAR AND CELLULAR NEUROSCIENCES., vol. 9, no. 1, January 1997 (1997-01-01), SAN DIEGO, US, pages 26 - 41, XP002109255, ISSN: 1044-7431 *

Also Published As

Publication number Publication date
AU2000299A (en) 1999-07-12
WO1999032622A2 (en) 1999-07-01

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