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WO1999045114A3 - Human semaphorin zsmf-7 - Google Patents

Human semaphorin zsmf-7 Download PDF

Info

Publication number
WO1999045114A3
WO1999045114A3 PCT/US1999/004758 US9904758W WO9945114A3 WO 1999045114 A3 WO1999045114 A3 WO 1999045114A3 US 9904758 W US9904758 W US 9904758W WO 9945114 A3 WO9945114 A3 WO 9945114A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
zsmf
human semaphorin
methods
semaphorin
Prior art date
Application number
PCT/US1999/004758
Other languages
French (fr)
Other versions
WO1999045114A2 (en
Inventor
James L Holloway
Catherine E Lofton-Day
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU29827/99A priority Critical patent/AU2982799A/en
Publication of WO1999045114A2 publication Critical patent/WO1999045114A2/en
Publication of WO1999045114A3 publication Critical patent/WO1999045114A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Semaphorin polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides are expressed in neuronal and lymphatic tissues. The polypeptides may be used within methods for detecting receptors that mediate neurite outgrowth, modulate cellular proliferation and/or differentiation, and immune response.
PCT/US1999/004758 1998-03-03 1999-03-03 Human semaphorin zsmf-7 WO1999045114A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU29827/99A AU2982799A (en) 1998-03-03 1999-03-03 Human semaphorin zsmf-7

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7661198P 1998-03-03 1998-03-03
US60/076,611 1998-03-03

Publications (2)

Publication Number Publication Date
WO1999045114A2 WO1999045114A2 (en) 1999-09-10
WO1999045114A3 true WO1999045114A3 (en) 1999-11-04

Family

ID=22133130

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/004758 WO1999045114A2 (en) 1998-03-03 1999-03-03 Human semaphorin zsmf-7

Country Status (2)

Country Link
AU (1) AU2982799A (en)
WO (1) WO1999045114A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892047A3 (en) 1997-07-09 2000-03-08 Hoechst Marion Roussel Deutschland GmbH Human and murine semaphorin L
WO1999058676A2 (en) * 1998-05-14 1999-11-18 Immunex Corporation Semaphorin polypeptides
AU770157B2 (en) * 1999-09-08 2004-02-12 Immunex Corporation Use of semaphorin for modulation of cellular efflux
WO2001032707A1 (en) * 1999-11-02 2001-05-10 Zymogenetics, Inc. Human semaphorin
AU2669501A (en) * 1999-11-30 2001-06-12 Smithkline Beecham Plc New use
AU2065501A (en) * 1999-12-06 2001-06-12 Zymogenetics Inc. Human semaphorin zsmf-16
AU2001245871B2 (en) 2000-03-20 2006-06-01 Lexicon Pharmaceuticals, Inc. Novel human secreted proteins and polynucleotides encoding the same
CN1329060A (en) * 2000-06-19 2002-01-02 上海博德基因开发有限公司 Polypeptide-human semaphorin protein 9 and polynucleotide for coding it
AUPS271902A0 (en) * 2002-05-31 2002-06-20 Griffith University Gene expression and multiple sclerosis
US20070010433A1 (en) * 2002-07-11 2007-01-11 Sema Aps Use of compounds capable of inhibiting the proteolytic processing of semaphorins for prevention, treatment, diagnosis and prognosis of an invasive disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892047A2 (en) * 1997-07-09 1999-01-20 Hoechst Marion Roussel Deutschland GmbH Human and murine semaphorin L

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892047A2 (en) * 1997-07-09 1999-01-20 Hoechst Marion Roussel Deutschland GmbH Human and murine semaphorin L

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ENSSER A ET AL: "Alcephaline herpesvirus type 1 has a semaphorin-like gene", JOURNAL OF GENERAL VIROLOGY., vol. 76, 1995, SOCIETY FOR GENERAL MICROBIOLOGY, READING., GB, pages 1063 - 1067, XP002113888, ISSN: 0022-1317 *
LANGE C ET AL: "New eukaryotic semaphorins with close homology to semaphorins of viruses", GENOMICS., vol. 51, 1 August 1998 (1998-08-01), SAN DIEGO., US, pages 340 - 350, XP002113887, ISSN: 0888-7543 *
XU X ET AL: "Human semaphorin K1 is glycosylphosphatidylinositol-linked and defines a new subfamily of viral-related semaphorins", JOURNAL OF BIOLOGICAL CHEMISTRY., vol. 273, no. 35, 28 August 1998 (1998-08-28), AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD., US, pages 22428 - 22434, XP002113886, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
WO1999045114A2 (en) 1999-09-10
AU2982799A (en) 1999-09-20

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