+

WO2018101578A1 - Dispositif de soins de la peau à rouleaux utilisant des micro-aiguilles - Google Patents

Dispositif de soins de la peau à rouleaux utilisant des micro-aiguilles Download PDF

Info

Publication number
WO2018101578A1
WO2018101578A1 PCT/KR2017/009583 KR2017009583W WO2018101578A1 WO 2018101578 A1 WO2018101578 A1 WO 2018101578A1 KR 2017009583 W KR2017009583 W KR 2017009583W WO 2018101578 A1 WO2018101578 A1 WO 2018101578A1
Authority
WO
WIPO (PCT)
Prior art keywords
roller
microneedle
microneedles
biodegradable
cosmetic material
Prior art date
Application number
PCT/KR2017/009583
Other languages
English (en)
Korean (ko)
Inventor
황광석
Original Assignee
(주)엔앤비랩
(주)이시스코스메틱
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by (주)엔앤비랩, (주)이시스코스메틱 filed Critical (주)엔앤비랩
Publication of WO2018101578A1 publication Critical patent/WO2018101578A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
    • A45D34/00—Containers or accessories specially adapted for handling liquid toiletry or cosmetic substances, e.g. perfumes
    • A45D2034/002—Accessories
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
    • A45D40/00—Casings or accessories specially adapted for storing or handling solid or pasty toiletry or cosmetic substances, e.g. shaving soaps or lipsticks
    • A45D2040/0006—Accessories
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
    • A45D2200/00—Details not otherwise provided for in A45D
    • A45D2200/10—Details of applicators
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
    • A45D34/00—Containers or accessories specially adapted for handling liquid toiletry or cosmetic substances, e.g. perfumes
    • A45D34/04—Appliances specially adapted for applying liquid, e.g. using roller or ball
    • A45D34/041—Appliances specially adapted for applying liquid, e.g. using roller or ball using a roller, a disc or a ball
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
    • A45D40/00—Casings or accessories specially adapted for storing or handling solid or pasty toiletry or cosmetic substances, e.g. shaving soaps or lipsticks
    • A45D40/26—Appliances specially adapted for applying pasty paint, e.g. using roller, using a ball
    • A45D40/261—Appliances specially adapted for applying pasty paint, e.g. using roller, using a ball using a ball, a roller or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0606—Face

Definitions

  • the present invention relates to a roller-type skin beauty device using a micro-needle, and more particularly, by placing a micro-needle containing a biodegradable cosmetic material on the surface of the roller, the user can easily and quickly inject a cosmetic material under the skin of a wide area
  • the present invention relates to a roller skin care device using a microneedle.
  • the method of supplying drugs to the human body is by injection method such as intravenous injection or intramuscular injection, oral administration method by oral administration of various formulations such as tablets and syrups, or by applying or applying ointment or paste. It is divided into percutaneous absorption method which absorbs into skin.
  • cosmetics such as cosmetics are absorbed into the skin using a transdermal absorption method.
  • the amount of collagen decreases with age, and thus wrinkles increase.
  • vitamin C, peptite, Hyaluronic acid is supplied.
  • the stratum corneum the outermost layer of the skin, often acts as a barrier. Injections may be used to efficiently deliver cosmetics to the epidermal and dermal layers, but commonly used needles with a diameter of 0.3 to 1.2 mm stimulate pain points in the skin.
  • the microneedle 10 made of a solid metal is often used by being disposed on the roller 20 as shown in FIG. 1 (Korean Patent Publication No. 10-2008-0057657, Korean Patent Publication No. 10-2010-0085571). Reference) In this case, the microneedle 10 disposed on the roller 20 punctures the micropores to the epidermal layer or the dermis layer, and causes the cosmetic material applied to the skin before or after the perforation to penetrate into the perforated micropores.
  • the roller-type skin care device 1 can easily puncture micropores in a desired area, whereas the micropores punctured by the microneedle are blocked by the contraction of the skin, and thus the cosmetic material is not delivered as intended. Many, there was a problem that the cosmetic material is applied to other than the perforated micro-pores and wasted. In addition, there was a problem that care must be taken in reuse due to contamination of microneedles.
  • a microneedle is processed using a polymer or the like (see Korean Patent Publication No. 10-2015-0138647), or a microneedle is processed into a biodegradable cosmetic material itself (see Korean Patent Publication No. 10-2015-0028248). Is developed and marketed.
  • Patch type products using microneedles can supply cosmetic materials through the hollow part of the microneedles, coat them on the surface of the microneedles, or solidify biodegradable cosmetics to penetrate the epidermis or dermis layer. As a result, the cosmetic substance is decomposed into the epidermal layer or the dermis layer and is supplied.
  • patch-shaped products may form microneedles in hatched areas of FIG. 2, and place adhesive sheets on the areas indicated by dotted lines and attach the release paper 40 to the patch to be attached to the skin. Since it is produced in a form that is, there is a limit in producing products of various shapes and sizes required according to the curvature, size, etc. of the face, and also there is a problem in that mass production is difficult or expensive to manufacture a mold.
  • Korean Patent No. 10-1676861 discloses a manufacturing apparatus capable of continuously producing a large amount of microneedle patches, by which the microneedle patch is easier to produce than before, but in a continuous sheet having a certain width There is a problem in that the utilization of the product is not lowered because the loss of the part left after cutting for the manufacture of the product as shown in FIG.
  • the present invention has been made to solve the problems of the prior art as described above, the biodegradable cosmetics to be directly delivered to the epidermal or dermal layer and at the same time easy to use on the desired face area, to facilitate the production of micro needle roller
  • the purpose of the present invention is to reduce the production cost, to facilitate the supply and replacement of the microneedle roller, and to prevent the contamination of the microneedle.
  • a handle portion having a connecting portion to which the roller is rotatably coupled and having a first shaft portion protruding or recessed in the connecting portion;
  • a roller having a second shaft portion recessed or protruding to be connected to the first shaft portion on both sides of the roller, and having a first guide portion for guiding and coupling the first shaft portion to the second shaft portion;
  • a cover having a roller supporting portion for placing the roller in the cover therein and having a second guide portion for guiding the first and second shaft portions to be connected to each other when the connecting portion of the handle portion is inserted;
  • the roller is separately packaged by a sealing material capable of sealing the inside of the cover from the outside after inserting only the roller with the microneedle portion into the cover.
  • the sheet disc for microneedles on the sheet which is easy to produce is cut and used, the unnecessary waste part is greatly reduced according to the cutting, thereby increasing productivity and reducing the production cost.
  • the biodegradable cosmetics are directly delivered to the epidermal layer or the dermis layer, and can be easily used on a desired face area, and the microneedle roller can be easily supplied and replaced, and the microneedles can be prevented from being contaminated.
  • 1 to 2 is a view showing a beauty product using a conventional microneedle.
  • Figure 3 is a perspective view showing the appearance of an embodiment of the present invention article.
  • FIG. 4 is a cross-sectional view showing the structure of a microneedle
  • Figure 5 is a cross-sectional view for explaining the connection structure of the roller and the handle portion
  • FIG. 6 is a view showing a coupling relationship between a cover and a roller.
  • FIG. 7 is a view showing another form of the first guide portion.
  • FIG. 9 is a view showing a form that is cut from the sheet disc for microneedle and attached to the roller.
  • connection portion 36 first shaft portion
  • sealing material 64 sealing material 66 second guide portion 68 gripping portion
  • the roller-type skin care device 1 using the microneedle of this embodiment includes a roller 20;
  • a surface of the microneedle 10 formed on the liner 12 is made of a biodegradable cosmetic material, and is cut from the microneedle sheet disc and attached to the circumferential surface of the roller 20;
  • the roller 20 is composed of a handle portion 30 is rotatably coupled.
  • the microneedle 10 is made of a biodegradable cosmetic material as shown in FIG. 4, which is an enlarged cross-sectional view of part I of FIG. 3.
  • Such cosmetic materials form microneedles in a form applied to the liner 12 having the microneedles 10 formed thereon (FIG. 4A) or adhered to the liner 12 (FIG. 4B).
  • Biodegradable cosmetics and liners are described in detail in the Republic of Korea Patent No. 10-1618523, even if a cosmetic material or a liner is manufactured with a new material that is newly developed, the components of the cosmetic material or liner affect the technical spirit of the present invention. No, it does not depart from the scope of the invention described in the claims of the present application.
  • Biodegradable cosmetic materials in the present application include those containing materials other than cosmetic materials added for molding the microneedles.
  • Liner refers to a thin film or sheet that supports the biodegradable cosmetic material that constitutes the microneedle.
  • Microneedles made of biodegradable cosmetics may be necessary to compensate for repeated puncture of the skin, which is decomposed by moisture in the living body and ends at the end.
  • the second needle 13 having different physical properties from the biodegradable cosmetic material exposed on the surface before decomposition is provided in the microneedles 10. This is because even if the biodegradable cosmetic material exposed on the surface before being punctured on the skin is melted and the sharpness of the microneedles 10 is damaged, the second needle 13 inside is exposed to continue puncturing the skin.
  • the second needle 13 may be made of a polymer material such as a biodegradable cosmetic material or a polymer having a higher rigidity than the biodegradable cosmetic material exposed on the surface before being perforated to the skin (Fig. 4 (c) and Fig. 4). (d) Note)
  • the roller having the microneedle portion 100 on its surface prepares a sheet disc for microneedles on a sheet made of a biodegradable cosmetic material on the surface of the microneedle 10 as shown in FIG. It can be produced by attaching the cut sheet in a wrapable form to the roller.
  • the sheet 50 may be adhered to the roller by applying the adhesive 50 to the back side of the sheet (the side opposite to the surface on which the microneedle is formed) or by applying the adhesive 50 to the surface of the roller 20. Since the sheet attached to the cylindrical roller has a rectangular shape, there is almost no discarded portion when cutting from the sheet disc for microneedles on the sheet, thus increasing productivity and lowering the production cost.
  • the roller 20 is rotatably axially connected to the connection part 35 of the handle part 30.
  • the connecting portion 35 of the handle portion 30 is provided with a protruding first shaft portion 36, and the roller 20 is fitted with each other and the second shaft portion 26 formed concave in the central axis of the roller 20 Is rotatably installed at the connecting portion (35).
  • the first shaft portion 36 protrudes and the second shaft portion 26 has been described as being concave in this embodiment, it is of course possible that the first shaft portion is concave and the second shaft portion is protruded.
  • the microneedles 10 of the present invention are made of a biodegradable cosmetic material, they can no longer be used when the microneedles are absorbed and extinguished in the skin. Therefore, it is desirable to remove the used rollers and to replace and use the new rollers. In addition, in order to prevent the microneedles from being inadvertently damaged during packaging, transportation, or use, it is also preferable to provide a cover 60 that can protect the roller.
  • the roller 20 and the cover 60 may be preferably packaged and supplied separately from the handle part 30 in consideration of hygiene as well as convenience in use.
  • the cover 60 includes a roller support 62 for supporting the roller 20 therein, and inserts the roller 20 into the cover 60 to support the roller 60.
  • the cover 60 is preferably sealed and supplied with a sealing material 64 (see FIG. 8).
  • the sealing material 64 the holding part 68 is further provided to facilitate separation from the cover 60. It is more preferable to do.
  • a first guide part 110 is provided to guide the engagement of the first and second shaft parts 36 and 26.
  • 110 is formed as a concave groove in the side of the roller 20 when the first shaft portion is in a protruding form (see FIG. 6), and the connection portion 35 when the first shaft portion 36 is recessed. It is preferable to form a concave groove along the inner surface of () (see FIG. 7).
  • the first and second shaft portions may be more easily coupled by the first guide portion.
  • the concave groove having the same size as the width of the connecting portion 35 is provided with the second guide portion 66 formed on the inner surface of the cover 60.
  • the second guide portion 66 may have a concave groove shape approximately equal to the width of the connection portion 35, and adjust the width of the cover to a size that allows the connection portion to fit inside the wall of the cover. It may be formed by.
  • the user pushes the connection part 35 of the handle part 30 to the cover 60 so that the handle part 30 and the roller 20 can be easily coupled. can do.
  • the sheet disc for microneedles on the sheet is easily cut and used, the unnecessary waste part can be greatly reduced according to the cutting, thereby increasing productivity and lowering the production cost, and it is biodegradable when used by a user.
  • the cosmetic material can be directly transferred to the epidermal or dermal layer, and can be easily used on the desired face area, and can easily supply and replace the microneedle roller, and can prevent contamination of the microneedles.

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un dispositif de soins de la peau à rouleaux utilisant des micro-aiguilles, de la présente invention, comprend : un rouleau; une partie de micro-aiguille dans laquelle la surface de micro-aiguilles formées sur une doublure de celle-ci est constituée d'un matériau cosmétique biodégradable, et qui est découpée à partir d'une plaque d'origine de feuille de micro-aiguille de façon à être fixée à la surface circonférentielle du rouleau; et une partie poignée à laquelle le rouleau est couplé de manière rotative.
PCT/KR2017/009583 2016-12-02 2017-09-01 Dispositif de soins de la peau à rouleaux utilisant des micro-aiguilles WO2018101578A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020160163146A KR101774803B1 (ko) 2016-12-02 2016-12-02 마이크로 니들을 이용한 롤러형 피부 미용기기 및 이를 위한 롤러의 제작방법
KR10-2016-0163146 2016-12-02

Publications (1)

Publication Number Publication Date
WO2018101578A1 true WO2018101578A1 (fr) 2018-06-07

Family

ID=59925013

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2017/009583 WO2018101578A1 (fr) 2016-12-02 2017-09-01 Dispositif de soins de la peau à rouleaux utilisant des micro-aiguilles

Country Status (2)

Country Link
KR (1) KR101774803B1 (fr)
WO (1) WO2018101578A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021256214A1 (fr) * 2020-06-17 2021-12-23 L'oreal Kit et procédé cosmétique utilisant une feuille à micro-aiguilles

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101866246B1 (ko) 2017-10-27 2018-06-11 주식회사 코스칼드바이오 구름성이 개선된 롤러형 피부미용기기
KR102076394B1 (ko) * 2017-10-30 2020-02-11 장은주 생체흡수 및 생체분해 소재의 주입기
KR20190053344A (ko) 2017-11-10 2019-05-20 (주)영진팩 지압 및 마사지 롤러 결합형 로션타입 내용물 용기
KR102047477B1 (ko) * 2017-11-21 2019-11-21 (주)디엔컴퍼니 롤러형 피부 미용기기용 롤러 키트
KR20190092212A (ko) 2018-01-30 2019-08-07 주식회사 에스더컴퍼니 미세침을 이용한 피부미용기구
KR102172203B1 (ko) 2018-06-04 2020-10-30 전진구 마사지 롤러 결합형 내용물 용기
KR200494645Y1 (ko) 2019-08-20 2021-11-22 한솔생명과학(주) 마사지형 화장품 용기
KR20210121559A (ko) 2020-03-30 2021-10-08 권한진 미세침이 만든 미세 구멍을 통해 효능 성분의 진입 효율을 높이기 위한 진입 촉진장치
KR20210136748A (ko) 2020-05-08 2021-11-17 주식회사 솔텍엔지니어링 피부용 자가 주입기구

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100907332B1 (ko) * 2006-07-05 2009-07-13 조철민 미세바늘들을 갖는 롤러장치 및 이의 제조방법
KR101028457B1 (ko) * 2008-08-07 2011-04-14 (주)마이티시스템 미세바늘 교환형 미세바늘 롤러 및 스탬프
KR20140044098A (ko) * 2012-10-04 2014-04-14 공광열 마이크로니들 롤러
JP5709530B2 (ja) * 2009-01-30 2015-04-30 久光製薬株式会社 マイクロニードルデバイス

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2338557A1 (fr) * 2009-12-23 2011-06-29 Debiotech S.A. Micro-aiguille soluble

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100907332B1 (ko) * 2006-07-05 2009-07-13 조철민 미세바늘들을 갖는 롤러장치 및 이의 제조방법
KR101028457B1 (ko) * 2008-08-07 2011-04-14 (주)마이티시스템 미세바늘 교환형 미세바늘 롤러 및 스탬프
JP5709530B2 (ja) * 2009-01-30 2015-04-30 久光製薬株式会社 マイクロニードルデバイス
KR20140044098A (ko) * 2012-10-04 2014-04-14 공광열 마이크로니들 롤러

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021256214A1 (fr) * 2020-06-17 2021-12-23 L'oreal Kit et procédé cosmétique utilisant une feuille à micro-aiguilles

Also Published As

Publication number Publication date
KR101774803B1 (ko) 2017-09-05

Similar Documents

Publication Publication Date Title
WO2018101578A1 (fr) Dispositif de soins de la peau à rouleaux utilisant des micro-aiguilles
US11998712B2 (en) Protective release sheet for microneedle patch
KR101033514B1 (ko) 유연한 미세바늘 패치 시스템 및 그 제작방법
US11633580B2 (en) Applicator for water-soluble sheet-shaped preparation
CN105916543B (zh) 微针单元以及微针组件
KR102206955B1 (ko) 마이크로니들 어레이 및 마이크로니들 시트
EP2865409B1 (fr) Corps en forme d'aiguilles et procédé de fabrication d'un corps en forme d'aiguilles
KR101747099B1 (ko) 생체적합성 고분자를 이용한 마이크로니들의 제조방법
WO2015186940A1 (fr) Timbre à micro-aiguilles et procédé de production associé
KR200494105Y1 (ko) 마이크로 니들 롤러 기기
WO2017003238A1 (fr) Structure de micro-aiguille capable de contrôler le dosage de médicament et la profondeur d'injection, et son procédé de production
WO2015186937A1 (fr) Timbre à micro-aiguilles et son procédé de production
WO2019083165A1 (fr) Dispositif de traitement de la peau du type à rouleaux ayant une aptitude au roulement améliorée
US10596040B2 (en) Transdermal administration device
CN217187427U (zh) 一种口腔黏膜用麻醉贴片
KR101785425B1 (ko) 약제용 패치 제조장치
CN215229247U (zh) 皮肤包覆敷贴
CN217865928U (zh) 一种微针贴片包装体及微针贴片产品
CN218129295U (zh) 一种医药用透皮贴剂
KR20240171882A (ko) 마이크로 니들패치 조립체 및 그 제조방법
KR20230153618A (ko) 마이크로 니들 패치
TW202442264A (zh) 可溶式微針貼片及其製造方法
KR20240001098U (ko) 마이크로니들 패치 및 이를 이용한 피부미용 마사지기

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 17875383

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 17875383

Country of ref document: EP

Kind code of ref document: A1

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载