+

WO2008130025A1 - Contenant de culture d'hépatocytes, et procédé de culture d'hépatocytes - Google Patents

Contenant de culture d'hépatocytes, et procédé de culture d'hépatocytes Download PDF

Info

Publication number
WO2008130025A1
WO2008130025A1 PCT/JP2008/057573 JP2008057573W WO2008130025A1 WO 2008130025 A1 WO2008130025 A1 WO 2008130025A1 JP 2008057573 W JP2008057573 W JP 2008057573W WO 2008130025 A1 WO2008130025 A1 WO 2008130025A1
Authority
WO
WIPO (PCT)
Prior art keywords
hepatocyte culture
microcontainers
culture container
container
hepatocyte
Prior art date
Application number
PCT/JP2008/057573
Other languages
English (en)
Japanese (ja)
Inventor
Hideki Taniguchi
Tomoko Ando
Go Tazaki
Hitoshi Tsuruta
Motohiro Fukuda
Original Assignee
Public University Corporation Yokohama City University
Kuraray Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Public University Corporation Yokohama City University, Kuraray Co., Ltd. filed Critical Public University Corporation Yokohama City University
Priority to JP2009510862A priority Critical patent/JPWO2008130025A1/ja
Publication of WO2008130025A1 publication Critical patent/WO2008130025A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne la fourniture d'un contenant de culture d'hépatocytes et un procédé de culture d'hépatocytes qui peut reproduire une fonction hépatique dans le corps vivant. Un contenant de culture d'hépatocytes (10) selon la présente invention est un contenant de culture d'hépatocytes (10) ayant une pluralité de microcontenants (11) sur la surface, et la zone inférieure de chacun des microcontenants (11) varie de 0,01 à 0,1 mm2, et la hauteur d'une paroi latérale (13) constituant chacun des microcontenants (11) varie de 25 à 150 µm. De plus, la forme du fond de chacun des microcontenants (11) est isotropique, et son axe majeur est de préférence dans la plage allant de 1 à 1,5 fois son axe mineur.
PCT/JP2008/057573 2007-04-18 2008-04-18 Contenant de culture d'hépatocytes, et procédé de culture d'hépatocytes WO2008130025A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009510862A JPWO2008130025A1 (ja) 2007-04-18 2008-04-18 肝細胞培養容器及び肝細胞培養方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007109183 2007-04-18
JP2007-109183 2007-04-18

Publications (1)

Publication Number Publication Date
WO2008130025A1 true WO2008130025A1 (fr) 2008-10-30

Family

ID=39875547

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/057573 WO2008130025A1 (fr) 2007-04-18 2008-04-18 Contenant de culture d'hépatocytes, et procédé de culture d'hépatocytes

Country Status (2)

Country Link
JP (1) JPWO2008130025A1 (fr)
WO (1) WO2008130025A1 (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009099152A1 (fr) 2008-02-06 2009-08-13 Public University Corporation Yokohama City University Méthode de culture cellulaire et méthode de criblage
WO2009099153A1 (fr) * 2008-02-06 2009-08-13 National University Corporation Nagoya University Méthode de culture cellulaire
WO2010047133A1 (fr) * 2008-10-24 2010-04-29 株式会社クラレ Procédé de stockage de cellules et procédé de transport de cellules
JP2010200679A (ja) * 2009-03-04 2010-09-16 Kuraray Co Ltd 細胞培養容器、細胞培養方法、および細胞評価方法
JP2012249547A (ja) * 2011-05-31 2012-12-20 Oji Holdings Corp 細胞培養用基材及びその製造方法
WO2014196204A1 (fr) * 2013-06-07 2014-12-11 株式会社クラレ Flacon à culture et procédé de culture
WO2015182159A1 (fr) * 2014-05-30 2015-12-03 株式会社クラレ Procédé de culture et masse cellulaire
WO2018003858A1 (fr) 2016-06-28 2018-01-04 国立研究開発法人農業・食品産業技術総合研究機構 Contenant pour cellule et son utilisation
WO2018135252A1 (fr) 2017-01-18 2018-07-26 国立研究開発法人農業・食品産業技術総合研究機構 Membrane semi-perméable et ses utilisations
WO2019116699A1 (fr) 2017-12-12 2019-06-20 国立研究開発法人農業・食品産業技術総合研究機構 Dispositif d'encapsulation de cellules avec tube d'aspiration et son utilisation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004154027A (ja) * 2002-11-05 2004-06-03 Foundation For The Promotion Of Industrial Science 細胞培養チャンバー
JP2006050975A (ja) * 2004-08-12 2006-02-23 Kuraray Co Ltd 細胞操作用基板およびそれを用いる灌流培養装置
JP2006191809A (ja) * 2005-01-11 2006-07-27 Kuraray Co Ltd 伸展方向が制御された細胞の培養方法
JP2006217845A (ja) * 2005-02-09 2006-08-24 Hitachi Medical Corp 付着性細胞の培養方法および培養装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004154027A (ja) * 2002-11-05 2004-06-03 Foundation For The Promotion Of Industrial Science 細胞培養チャンバー
JP2006050975A (ja) * 2004-08-12 2006-02-23 Kuraray Co Ltd 細胞操作用基板およびそれを用いる灌流培養装置
JP2006191809A (ja) * 2005-01-11 2006-07-27 Kuraray Co Ltd 伸展方向が制御された細胞の培養方法
JP2006217845A (ja) * 2005-02-09 2006-08-24 Hitachi Medical Corp 付着性細胞の培養方法および培養装置

Cited By (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5940758B2 (ja) * 2008-02-06 2016-06-29 国立大学法人名古屋大学 細胞培養方法
WO2009099153A1 (fr) * 2008-02-06 2009-08-13 National University Corporation Nagoya University Méthode de culture cellulaire
JPWO2009099153A1 (ja) * 2008-02-06 2011-05-26 国立大学法人名古屋大学 細胞培養方法
JPWO2009099152A1 (ja) * 2008-02-06 2011-05-26 公立大学法人横浜市立大学 細胞培養方法及びスクリーニング方法
WO2009099152A1 (fr) 2008-02-06 2009-08-13 Public University Corporation Yokohama City University Méthode de culture cellulaire et méthode de criblage
US9428721B2 (en) 2008-02-06 2016-08-30 Public University Corporation Yokohama City University Cell culture of fetal liver in layered state in a partitioned micro-space
JP5932206B2 (ja) * 2008-02-06 2016-06-08 公立大学法人横浜市立大学 細胞培養方法及びスクリーニング方法
WO2010047133A1 (fr) * 2008-10-24 2010-04-29 株式会社クラレ Procédé de stockage de cellules et procédé de transport de cellules
JP2010200679A (ja) * 2009-03-04 2010-09-16 Kuraray Co Ltd 細胞培養容器、細胞培養方法、および細胞評価方法
JP2012249547A (ja) * 2011-05-31 2012-12-20 Oji Holdings Corp 細胞培養用基材及びその製造方法
US10494593B2 (en) 2013-06-07 2019-12-03 Corning Incorporated Culture chamber and culture method
JP2021129590A (ja) * 2013-06-07 2021-09-09 コーニング インコーポレイテッド 培養方法
US11866682B1 (en) 2013-06-07 2024-01-09 Corning Incorporated Culture chamber and culture method
JPWO2014196204A1 (ja) * 2013-06-07 2017-02-23 株式会社クラレ 培養容器及び培養方法
JP7219303B2 (ja) 2013-06-07 2023-02-07 コーニング インコーポレイテッド 培養方法
US11473046B2 (en) 2013-06-07 2022-10-18 Corning Incorporated Culture chamber and culture method
JP2020000255A (ja) * 2013-06-07 2020-01-09 コーニング インコーポレイテッド 培養容器及び培養方法
WO2014196204A1 (fr) * 2013-06-07 2014-12-11 株式会社クラレ Flacon à culture et procédé de culture
JP7125717B2 (ja) 2014-05-30 2022-08-25 コーニング インコーポレイテッド 培養方法
CN106459925A (zh) * 2014-05-30 2017-02-22 株式会社可乐丽 培养方法和细胞团
JP2019193666A (ja) * 2014-05-30 2019-11-07 コーニング インコーポレイテッド 培養方法
JPWO2015182159A1 (ja) * 2014-05-30 2017-04-20 株式会社クラレ 培養方法及び細胞塊
CN106459925B (zh) * 2014-05-30 2019-12-27 株式会社可乐丽 培养方法和细胞团
US20170183621A1 (en) * 2014-05-30 2017-06-29 Kuraray Co., Ltd. Culture method and cell cluster
US10752879B2 (en) 2014-05-30 2020-08-25 Corning Incorporated Culture method and cell cluster
WO2015182159A1 (fr) * 2014-05-30 2015-12-03 株式会社クラレ Procédé de culture et masse cellulaire
WO2018003858A1 (fr) 2016-06-28 2018-01-04 国立研究開発法人農業・食品産業技術総合研究機構 Contenant pour cellule et son utilisation
WO2018135252A1 (fr) 2017-01-18 2018-07-26 国立研究開発法人農業・食品産業技術総合研究機構 Membrane semi-perméable et ses utilisations
KR20190104159A (ko) 2017-01-18 2019-09-06 고쿠리츠겐큐가이하츠호징 노우교 · 쇼쿠힝 산교기쥬츠 소고겐큐기코 반투막 및 그 사용
KR20200079540A (ko) 2017-12-12 2020-07-03 고쿠리츠겐큐가이하츠호징 노우교 · 쇼쿠힝 산교기쥬츠 소고겐큐기코 흡인관을 구비한 세포 봉입용 디바이스 및 그 사용
WO2019116699A1 (fr) 2017-12-12 2019-06-20 国立研究開発法人農業・食品産業技術総合研究機構 Dispositif d'encapsulation de cellules avec tube d'aspiration et son utilisation

Also Published As

Publication number Publication date
JPWO2008130025A1 (ja) 2010-07-22

Similar Documents

Publication Publication Date Title
WO2008130025A1 (fr) Contenant de culture d'hépatocytes, et procédé de culture d'hépatocytes
USD616183S1 (en) Portion of a shoe upper
USD591556S1 (en) Top for beverage container
USD627758S1 (en) Media player
USD587995S1 (en) Propellor cup tray
USD633286S1 (en) Portion of a shoe
USD540194S1 (en) Container
USD606126S1 (en) Playing surface for toy top
USD612659S1 (en) Wine aerator
USD610011S1 (en) Container
USD601852S1 (en) Growin' up cup
USD613598S1 (en) Container
USD599630S1 (en) Soil reinforcing retaining wall anchor
USD725942S1 (en) Heel support
USD598743S1 (en) Dispense cup
USD668352S1 (en) Suspended ceiling wall angle
USD561833S1 (en) Pen clip
USD652152S1 (en) Swell ceiling or wall panel
USD644751S1 (en) Combined ceiling and wall panel
USD604570S1 (en) Snowflake spatula
USD507755S1 (en) Container
USD712536S1 (en) Biological fluid container
USD552421S1 (en) Drinking cup
USD633079S1 (en) Media player
USD565883S1 (en) Supernova rug

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08740628

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2009510862

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08740628

Country of ref document: EP

Kind code of ref document: A1

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载