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WO2008153179A1 - 脂肪組織由来多系統前駆細胞 - Google Patents

脂肪組織由来多系統前駆細胞 Download PDF

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Publication number
WO2008153179A1
WO2008153179A1 PCT/JP2008/060977 JP2008060977W WO2008153179A1 WO 2008153179 A1 WO2008153179 A1 WO 2008153179A1 JP 2008060977 W JP2008060977 W JP 2008060977W WO 2008153179 A1 WO2008153179 A1 WO 2008153179A1
Authority
WO
WIPO (PCT)
Prior art keywords
progenitor cell
tissue
multipotent progenitor
adipose
derived multipotent
Prior art date
Application number
PCT/JP2008/060977
Other languages
English (en)
French (fr)
Inventor
Akifumi Matsuyama
Hiroshi Komoda
Hanayuki Ohkura
Yoshiki Sawa
Original Assignee
Akifumi Matsuyama
Hiroshi Komoda
Hanayuki Ohkura
Yoshiki Sawa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akifumi Matsuyama, Hiroshi Komoda, Hanayuki Ohkura, Yoshiki Sawa filed Critical Akifumi Matsuyama
Priority to JP2009519332A priority Critical patent/JPWO2008153179A1/ja
Priority to EP08765660A priority patent/EP2166084A4/en
Priority to US12/664,343 priority patent/US9845458B2/en
Publication of WO2008153179A1 publication Critical patent/WO2008153179A1/ja
Priority to US15/825,245 priority patent/US20180072994A1/en
Priority to US15/827,778 priority patent/US20180100141A1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

　本発明は、脂肪組織由来多系統前駆細胞を含む細胞集団、脂肪組織から脂肪組織由来多系統前駆細胞を得る方法であって、（ａ）脂肪組織由来細胞集団から赤血球を除去し、前脂肪組織由来多系統前駆細胞集団を形成し；次に、（ｂ）該前脂肪組織由来多系統前駆細胞集団から脂肪組織由来多系統前駆細胞以外の細胞を除去し、脂肪組織由来多系統前駆細胞を得る、工程を含む方法およびそれにより得ることのできる脂肪組織由来多系統前駆細胞を提供する。
PCT/JP2008/060977 2007-06-14 2008-06-16 脂肪組織由来多系統前駆細胞 WO2008153179A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2009519332A JPWO2008153179A1 (ja) 2007-06-14 2008-06-16 脂肪組織由来多系統前駆細胞
EP08765660A EP2166084A4 (en) 2007-06-14 2008-06-16 MULTIPOTENTE PRECURSOR CELLS FROM FAT
US12/664,343 US9845458B2 (en) 2007-06-14 2008-06-16 Multipotent progenitor cell derived from adipose tissue
US15/825,245 US20180072994A1 (en) 2007-06-14 2017-11-29 Multipotent progenitor cell derived from adipose tissue
US15/827,778 US20180100141A1 (en) 2007-06-14 2017-11-30 Multipotent progenitor cell derived from adipose tissue

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007157388 2007-06-14
JP2007-157387 2007-06-14
JP2007157387 2007-06-14
JP2007-157388 2007-06-14

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US66434309A Continuation 2007-06-14 2009-12-29

Publications (1)

Publication Number Publication Date
WO2008153179A1 true WO2008153179A1 (ja) 2008-12-18

Family

ID=40129780

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/JP2008/060977 WO2008153179A1 (ja) 2007-06-14 2008-06-16 脂肪組織由来多系統前駆細胞
PCT/JP2008/060980 WO2008153180A1 (ja) 2007-06-14 2008-06-16 脂肪組織由来細胞から肝小葉様細胞塊を得る方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/060980 WO2008153180A1 (ja) 2007-06-14 2008-06-16 脂肪組織由来細胞から肝小葉様細胞塊を得る方法

Country Status (4)

Country Link
US (4) US20100183568A1 (ja)
EP (2) EP2172541A4 (ja)
JP (2) JPWO2008153179A1 (ja)
WO (2) WO2008153179A1 (ja)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011024962A1 (ja) 2009-08-28 2011-03-03 財団法人先端医療振興財団 肝臓関連疾患治療薬
WO2013162057A1 (ja) 2012-04-25 2013-10-31 独立行政法人理化学研究所 心筋指向性細胞を含む細胞製剤
JP2014030423A (ja) * 2012-07-11 2014-02-20 Kinki Univ 脂肪組織由来体性幹細胞の製造方法
WO2016013352A1 (ja) * 2014-07-23 2016-01-28 学校法人日本大学 脱分化脂肪細胞の製造方法
WO2017126549A1 (ja) * 2016-01-19 2017-07-27 国立大学法人大阪大学 心疾患の治療のための移植材料
WO2018110686A1 (ja) 2016-12-16 2018-06-21 有限会社大阪空気機械サービス 組織治癒剤
WO2019240296A1 (ja) 2018-06-15 2019-12-19 有限会社大阪空気機械サービス 組織治癒剤

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US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
JP5804342B2 (ja) * 2010-09-11 2015-11-04 国立大学法人金沢大学 脂肪組織由来間質細胞群を含む肝炎治療剤
CA2919374C (en) 2013-07-30 2019-12-03 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
GB2535217B (en) * 2015-02-13 2019-10-09 Delta Of Sweden Ab Modelling compound
EP3297694A1 (en) 2015-05-21 2018-03-28 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
CN110628713A (zh) * 2019-11-07 2019-12-31 安徽科门生物科技有限公司 一种脂肪源干细胞提取制备方法
EP4118188A1 (en) 2020-03-11 2023-01-18 Bit Bio Limited Method of generating hepatic cells

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JP2002537849A (ja) 1999-03-10 2002-11-12 ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション 脂肪由来の幹細胞および格子
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Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8784803B2 (en) 2009-08-28 2014-07-22 Osaka Air Machine Service, Ltd. Therapeutic agent for liver-related diseases
JP4965000B2 (ja) * 2009-08-28 2012-07-04 財団法人先端医療振興財団 肝臓関連疾患治療薬
WO2011024962A1 (ja) 2009-08-28 2011-03-03 財団法人先端医療振興財団 肝臓関連疾患治療薬
US9644181B2 (en) 2012-04-25 2017-05-09 Riken Cell preparation containing myocardium-committed cell
JPWO2013162057A1 (ja) * 2012-04-25 2015-12-24 国立研究開発法人理化学研究所 心筋指向性細胞を含む細胞製剤
WO2013162057A1 (ja) 2012-04-25 2013-10-31 独立行政法人理化学研究所 心筋指向性細胞を含む細胞製剤
JP2014030423A (ja) * 2012-07-11 2014-02-20 Kinki Univ 脂肪組織由来体性幹細胞の製造方法
WO2016013352A1 (ja) * 2014-07-23 2016-01-28 学校法人日本大学 脱分化脂肪細胞の製造方法
JP5991687B2 (ja) * 2014-07-23 2016-09-14 学校法人日本大学 脱分化脂肪細胞の製造方法
CN108472319B (zh) * 2016-01-19 2021-12-28 国立大学法人大阪大学 用于治疗心脏病的移植材料
WO2017126549A1 (ja) * 2016-01-19 2017-07-27 国立大学法人大阪大学 心疾患の治療のための移植材料
CN108472319A (zh) * 2016-01-19 2018-08-31 国立大学法人大阪大学 用于治疗心脏病的移植材料
JPWO2017126549A1 (ja) * 2016-01-19 2018-11-08 国立大学法人大阪大学 心疾患の治療のための移植材料
US12226436B2 (en) 2016-01-19 2025-02-18 Rohto Pharmaceutical Co., Ltd. Transplant material for treatment of heart disease
WO2018110686A1 (ja) 2016-12-16 2018-06-21 有限会社大阪空気機械サービス 組織治癒剤
JP7237301B2 (ja) 2016-12-16 2023-03-13 有限会社大阪空気機械サービス 組織治癒剤
JP2019218271A (ja) * 2018-06-15 2019-12-26 有限会社大阪空気機械サービス 組織治癒剤
WO2019240296A1 (ja) 2018-06-15 2019-12-19 有限会社大阪空気機械サービス 組織治癒剤

Also Published As

Publication number Publication date
EP2172541A4 (en) 2010-06-30
US20100183568A1 (en) 2010-07-22
EP2172541A1 (en) 2010-04-07
EP2166084A1 (en) 2010-03-24
US20180072994A1 (en) 2018-03-15
US9845458B2 (en) 2017-12-19
US20100151574A1 (en) 2010-06-17
JPWO2008153180A1 (ja) 2010-08-26
JPWO2008153179A1 (ja) 2010-08-26
WO2008153180A1 (ja) 2008-12-18
US20180100141A1 (en) 2018-04-12
EP2166084A4 (en) 2010-06-23

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