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WO2008152006A1 - Procédé de dépyrogénation de corps creux en verre et tunnel à air chaud utilisé à cette fin - Google Patents

Procédé de dépyrogénation de corps creux en verre et tunnel à air chaud utilisé à cette fin Download PDF

Info

Publication number
WO2008152006A1
WO2008152006A1 PCT/EP2008/057122 EP2008057122W WO2008152006A1 WO 2008152006 A1 WO2008152006 A1 WO 2008152006A1 EP 2008057122 W EP2008057122 W EP 2008057122W WO 2008152006 A1 WO2008152006 A1 WO 2008152006A1
Authority
WO
WIPO (PCT)
Prior art keywords
hot air
air tunnel
sound signals
microphone
computer
Prior art date
Application number
PCT/EP2008/057122
Other languages
German (de)
English (en)
Inventor
Jens Scheibner
Jelena Laube
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of WO2008152006A1 publication Critical patent/WO2008152006A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04—Heat
    • A61L2/06—Hot gas

Definitions

  • the invention relates to a process for the depyrogenation of glass hollow bodies, in particular vials, in a hot air tunnel.
  • the object in the method is achieved in that the interior of the hot air tunnel is acoustically monitored.
  • production staff can selectively isolate the affected area and remove vials from the vicinity of the cracked vial from the production process, as they may be contaminated with glass splinters. This is accompanied by the reduction of the risk of a contaminated product.
  • the sound signals are evaluated online during depyrogenation computer-controlled.
  • the evaluation can be carried out, for example, on the basis of stored comparison values. Due to the continuous monitoring of the process by the detection of the sound signals and possibly further key figures relevant to the product and process quality, which include, for example, the sterilization temperature or a residence time, data can be obtained by means of a statistical process control to detect vulnerabilities and improve the process.
  • the object is achieved in that at least one microphone is disposed inside the hot air tunnel, which is connected to the evaluation of sound signals with a signal processor.
  • the signal processor can be both a software and a hardware solution.
  • the microphone preferably comprises a housing made of a high-alloy, in particular sterilizable or disinfectable, steel.
  • a high-alloy in particular sterilizable or disinfectable, steel.
  • the skilled worker is aware of various alloys, so-called stainless steels, in order to ensure problem-free cleaning and surface disinfection.
  • the microphone is designed and arranged accordingly to avoid turbulence in the hot air tunnel. This means that, for example, the microfluidically positioned microphone has a comparatively small size and the housing of the microphone has a corresponding flow geometry.
  • the microphone is coupled via a cable, a radio link or an opto-electronic connection to a computer.
  • the computer may be a computer for controlling the hot air tunnel or a separate computer, which communicates, for example, via a network with other computers.
  • the computer comprises a storage medium for storing sound signals.
  • the stored data is used to reproduce the process.
  • the stored sound signals also serve to take corrective and preventive measures, since an exact problem analysis with the inclusion of further process data, such as the temperature or the residence time, is possible.
  • the signal processor is advantageously connected to an optical and / or audible alarm device.
  • the alarm device may comprise, for example, an all-round light, a flashing light and / or a siren and is controlled by the computer.
  • FIG. 1 shows a schematic representation of a hot air tunnel according to the invention for carrying out the method according to the invention.
  • the hot air tunnel 1 is used for depyrogenation of glass hollow bodies 2, which are formed as vials 3, and is to be heated to a to be detected with a thermometer 4 sterilization temperature.
  • the thermometer 4 is coupled to a computer 5 which is connected both to a heating device 6 and to a ventilation device 9 for a particle-free and laminar air flow in the interior of the hot-air tunnel 1.
  • a microphone 7 is arranged inside the hot air tunnel 1, which is connected to the evaluation of sound signals with a computer 5 associated signal processor. Detects the signal processor of the computer 5 sound signals that differ from the signals of a normal course of the process, one with the
  • Computer-coupled alarm device 8 is driven to signal this circumstance so that operators of the hot air tunnel 1 after depyrogenation glass splinters and vials 3 in the vicinity of the cracked vial 3, which may be contaminated with glass splinters can remove.

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

La présente invention concerne un procédé de dépyrogénation de corps creux en verre (2), notamment de flacons (3), dans un tunnel à air chaud (1). Selon le procédé, l'intérieur du tunnel à air chaud (1) est soumis à un contrôle acoustique.
PCT/EP2008/057122 2007-06-11 2008-06-06 Procédé de dépyrogénation de corps creux en verre et tunnel à air chaud utilisé à cette fin WO2008152006A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200710026872 DE102007026872A1 (de) 2007-06-11 2007-06-11 Verfahren zur Depyrogenisierung von Glashohlkörpern und Heißlufttunnel dazu
DE102007026872.8 2007-06-11

Publications (1)

Publication Number Publication Date
WO2008152006A1 true WO2008152006A1 (fr) 2008-12-18

Family

ID=39714055

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/057122 WO2008152006A1 (fr) 2007-06-11 2008-06-06 Procédé de dépyrogénation de corps creux en verre et tunnel à air chaud utilisé à cette fin

Country Status (2)

Country Link
DE (1) DE102007026872A1 (fr)
WO (1) WO2008152006A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202300004290A1 (it) 2023-03-08 2024-09-08 Gerardo FUMAGALLI Apparato di depirogenazione e/o sterilizzazione per flaconi e/o contenitori

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981003702A1 (fr) * 1980-06-19 1981-12-24 Boekels & Co H Procede et dispositif de surveillance acoustique de machines et/ou d'installations
US4846669A (en) * 1988-05-13 1989-07-11 Despatch Industries, Inc. Continuous material heating oven
WO2001042863A1 (fr) * 1999-12-08 2001-06-14 Siemens Aktiengesellschaft Dispositif et procede de surveillance (vibro-)acoustique d'un processus technologique et/ou de production
DE10138938A1 (de) * 2001-08-08 2003-02-20 Bosch Gmbh Robert Verfahren und Vorrichtung zur Sterilisation von Behältnissen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981003702A1 (fr) * 1980-06-19 1981-12-24 Boekels & Co H Procede et dispositif de surveillance acoustique de machines et/ou d'installations
US4846669A (en) * 1988-05-13 1989-07-11 Despatch Industries, Inc. Continuous material heating oven
WO2001042863A1 (fr) * 1999-12-08 2001-06-14 Siemens Aktiengesellschaft Dispositif et procede de surveillance (vibro-)acoustique d'un processus technologique et/ou de production
DE10138938A1 (de) * 2001-08-08 2003-02-20 Bosch Gmbh Robert Verfahren und Vorrichtung zur Sterilisation von Behältnissen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202300004290A1 (it) 2023-03-08 2024-09-08 Gerardo FUMAGALLI Apparato di depirogenazione e/o sterilizzazione per flaconi e/o contenitori

Also Published As

Publication number Publication date
DE102007026872A1 (de) 2008-12-24

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