WO2008149841A1 - β-フルオロ-α,β-不飽和カルボニル化合物の製造方法 - Google Patents
β-フルオロ-α,β-不飽和カルボニル化合物の製造方法 Download PDFInfo
- Publication number
- WO2008149841A1 WO2008149841A1 PCT/JP2008/060147 JP2008060147W WO2008149841A1 WO 2008149841 A1 WO2008149841 A1 WO 2008149841A1 JP 2008060147 W JP2008060147 W JP 2008060147W WO 2008149841 A1 WO2008149841 A1 WO 2008149841A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fluoro
- producing
- carbonyl compound
- unsaturated carbonyl
- compound
- Prior art date
Links
- 150000001728 carbonyl compounds Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- MDQRDWAGHRLBPA-UHFFFAOYSA-N fluoroamine Chemical compound FN MDQRDWAGHRLBPA-UHFFFAOYSA-N 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/227—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
医薬品等の機能化学品用途に於いて有用なβ-フルオロ-α,β-不飽和カルボニル化合物を高収率、高選択率に製造できる工業的に優れた製造方法に関する。 β-ジカルボニル化合物と特定のフルオロアミンとを反応させる方法である。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009517859A JPWO2008149841A1 (ja) | 2007-06-08 | 2008-06-02 | β−フルオロ−α,β−不飽和カルボニル化合物の製造方法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-152608 | 2007-06-08 | ||
JP2007152608 | 2007-06-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008149841A1 true WO2008149841A1 (ja) | 2008-12-11 |
Family
ID=40093657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/060147 WO2008149841A1 (ja) | 2007-06-08 | 2008-06-02 | β-フルオロ-α,β-不飽和カルボニル化合物の製造方法 |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPWO2008149841A1 (ja) |
WO (1) | WO2008149841A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013508446A (ja) * | 2009-11-05 | 2013-03-07 | ロディア オペレーションズ | アルキルヒドロペルオキシド化合物の製造方法 |
-
2008
- 2008-06-02 JP JP2009517859A patent/JPWO2008149841A1/ja not_active Withdrawn
- 2008-06-02 WO PCT/JP2008/060147 patent/WO2008149841A1/ja active Application Filing
Non-Patent Citations (3)
Title |
---|
KOBAYASHI S. ET AL., TETRAHEDRON LETTERS, vol. 45, no. 6, 2 April 2004 (2004-04-02), pages 1287 - 1289, XP004484833 * |
KOBAYASHI S. ET AL., TETRAHEDRON, vol. 60, no. 32, 2 August 2004 (2004-08-02), pages 6923 - 6930, XP004522095 * |
STEPANOV I.V. ET AL., ZHURNAL ORGANICHESKOI KHIMII, vol. 22, no. 1, 1986, pages 227 - 228 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013508446A (ja) * | 2009-11-05 | 2013-03-07 | ロディア オペレーションズ | アルキルヒドロペルオキシド化合物の製造方法 |
JP2015078239A (ja) * | 2009-11-05 | 2015-04-23 | ロディア オペレーションズRhodia Operations | アルキルヒドロペルオキシド化合物の製造方法 |
Also Published As
Publication number | Publication date |
---|---|
JPWO2008149841A1 (ja) | 2010-08-26 |
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