WO2008019651A3 - Dispositif de détermination de substances, procédé de réalisation et utilisation de ce dispositif - Google Patents
Dispositif de détermination de substances, procédé de réalisation et utilisation de ce dispositif Download PDFInfo
- Publication number
- WO2008019651A3 WO2008019651A3 PCT/DE2007/001362 DE2007001362W WO2008019651A3 WO 2008019651 A3 WO2008019651 A3 WO 2008019651A3 DE 2007001362 W DE2007001362 W DE 2007001362W WO 2008019651 A3 WO2008019651 A3 WO 2008019651A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- substance
- arrangement
- insulating layer
- examination
- substrate
- Prior art date
Links
- 239000000126 substance Substances 0.000 title abstract 14
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000758 substrate Substances 0.000 abstract 7
- 239000004065 semiconductor Substances 0.000 abstract 3
- 230000008878 coupling Effects 0.000 abstract 2
- 238000010168 coupling process Methods 0.000 abstract 2
- 238000005859 coupling reaction Methods 0.000 abstract 2
- 238000000018 DNA microarray Methods 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
L'invention concerne un dispositif et son utilisation pour déterminer de manière spécifique des substances d'échantillons, notamment une biopuce comprenant un support sur lequel se trouve une couche de liaison. Le dispositif comporte un support sur lequel est formée une couche de liaison à laquelle est couplée une substance de contrôle. Le support est semi-conducteur et la couche de liaison est au moins une couche d'isolation inorganique formée sur le support. Sur et/ou dans la couche d'isolation, au moins une zone est soumise à l'action d'au moins un milieu et d'au moins une substance de contrôle organique. Dans cette zone, la couche d'isolation est couplée à la substance de contrôle, laquelle peut interagir avec une substance d'essai. L'invention porte également sur un procédé de réalisation de ce dispositif, selon lequel au moins une zone d'une couche d'isolation inorganique formée sur un support est soumise à l'action d'au moins un milieu et d'au moins une substance de contrôle organique, et des interactions entre la substance de contrôle organique et la couche d'isolation inorganique provoque un couplage entre la substance de contrôle organique et la couche d'isolation inorganique, ladite zone étant formée pour interagir avec une substance d'essai et/ou interagissant avec cette substance d'essai lorsqu'elle est appliquée.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006036528.3 | 2006-07-31 | ||
DE102006036528 | 2006-07-31 | ||
DE102006051482A DE102006051482A1 (de) | 2006-07-31 | 2006-10-31 | Anordnung zum Erfassen von Substanzen, Herstellung der Anordnung und ihre Verwendung |
DE102006051482.3 | 2006-10-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008019651A2 WO2008019651A2 (fr) | 2008-02-21 |
WO2008019651A3 true WO2008019651A3 (fr) | 2008-06-05 |
Family
ID=38922189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE2007/001362 WO2008019651A2 (fr) | 2006-07-31 | 2007-07-31 | Dispositif de détermination de substances, procédé de réalisation et utilisation de ce dispositif |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE102006051482A1 (fr) |
WO (1) | WO2008019651A2 (fr) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1215186A1 (fr) * | 2000-12-14 | 2002-06-19 | Commissariat A L'energie Atomique | Support solide pour l'immobilisation d'oligonucléotides |
WO2002048691A1 (fr) * | 2000-12-14 | 2002-06-20 | Commissariat A L'energie Atomique | Dispositif de renforcement de fluorescence large bande a faibles pertes et capteur optique biologique ou chimique l'utilisant. |
US20030082658A1 (en) * | 1998-04-10 | 2003-05-01 | Francois Mallet | Method for fixing a biological molecule on a support surface |
EP1364702A2 (fr) * | 2002-05-15 | 2003-11-26 | Samsung Electronics Co., Ltd. | Procédé de fabrication d'une plaque matrice de biomolecules avec des zones hydrophiles et hydrophobes |
EP1542009A1 (fr) * | 2002-08-12 | 2005-06-15 | Hitachi High-Technologies Corporation | Procede de detection d'acide nucleique par utilisation de microreseaux d'adn, et appareil de detection d'acide nucleique |
US20060121501A1 (en) * | 2004-10-22 | 2006-06-08 | Stanislaw Burzynski | Method for immobilizing molecular probes to a semiconductor oxide surface |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL140949A0 (en) * | 2001-01-17 | 2002-02-10 | Yeda Res & Dev | Nitric oxide (no) detector |
US6707038B2 (en) * | 2001-02-14 | 2004-03-16 | Picoliter Inc. | Method and system using acoustic ejection for selective fluid deposition on a nonuniform sample surface |
AU2002314734B2 (en) * | 2001-03-30 | 2007-08-30 | Ge Healthcare Bio-Sciences Ab | P450 single nucleotide polymorphism biochip analysis |
US10539561B1 (en) * | 2001-08-30 | 2020-01-21 | Customarray, Inc. | Enzyme-amplified redox microarray detection process |
US20060194327A1 (en) * | 2003-07-30 | 2006-08-31 | Koninklijke Philips Electronics N.V. | On-chip magnetic particle sensor with improved snr |
JP4202391B2 (ja) * | 2004-03-17 | 2008-12-24 | パナソニック株式会社 | バイオチップの製造方法、プローブ溶液、および、バイオチップ |
DE102004021904B4 (de) * | 2004-05-04 | 2011-08-18 | Carl Zeiss Microlmaging GmbH, 07745 | Verfahren und Vorrichtung zur Erzeugung einer Analyseanordnung mit diskreten, separaten Messbereichen zur biologischen, biochemischen oder chemischen Analyse |
US7364898B2 (en) * | 2004-05-04 | 2008-04-29 | Eppendorf Ag | Customized micro-array construction and its use for target molecule detection |
-
2006
- 2006-10-31 DE DE102006051482A patent/DE102006051482A1/de not_active Withdrawn
-
2007
- 2007-07-31 WO PCT/DE2007/001362 patent/WO2008019651A2/fr active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030082658A1 (en) * | 1998-04-10 | 2003-05-01 | Francois Mallet | Method for fixing a biological molecule on a support surface |
EP1215186A1 (fr) * | 2000-12-14 | 2002-06-19 | Commissariat A L'energie Atomique | Support solide pour l'immobilisation d'oligonucléotides |
WO2002048691A1 (fr) * | 2000-12-14 | 2002-06-20 | Commissariat A L'energie Atomique | Dispositif de renforcement de fluorescence large bande a faibles pertes et capteur optique biologique ou chimique l'utilisant. |
EP1364702A2 (fr) * | 2002-05-15 | 2003-11-26 | Samsung Electronics Co., Ltd. | Procédé de fabrication d'une plaque matrice de biomolecules avec des zones hydrophiles et hydrophobes |
EP1542009A1 (fr) * | 2002-08-12 | 2005-06-15 | Hitachi High-Technologies Corporation | Procede de detection d'acide nucleique par utilisation de microreseaux d'adn, et appareil de detection d'acide nucleique |
US20060121501A1 (en) * | 2004-10-22 | 2006-06-08 | Stanislaw Burzynski | Method for immobilizing molecular probes to a semiconductor oxide surface |
Also Published As
Publication number | Publication date |
---|---|
WO2008019651A2 (fr) | 2008-02-21 |
DE102006051482A1 (de) | 2008-02-14 |
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