WO2008066878A3 - Procédés et produits utilisés pour diagnostiquer le cancer - Google Patents
Procédés et produits utilisés pour diagnostiquer le cancer Download PDFInfo
- Publication number
- WO2008066878A3 WO2008066878A3 PCT/US2007/024553 US2007024553W WO2008066878A3 WO 2008066878 A3 WO2008066878 A3 WO 2008066878A3 US 2007024553 W US2007024553 W US 2007024553W WO 2008066878 A3 WO2008066878 A3 WO 2008066878A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- cancer
- products
- diagnosing cancer
- detection
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 230000011987 methylation Effects 0.000 abstract 3
- 238000007069 methylation reaction Methods 0.000 abstract 3
- -1 PCSKl Proteins 0.000 abstract 2
- 208000006994 Precancerous Conditions Diseases 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 102100025331 Cadherin-8 Human genes 0.000 abstract 1
- 102100029846 Glutaminyl-peptide cyclotransferase Human genes 0.000 abstract 1
- 101000935095 Homo sapiens Cadherin-8 Proteins 0.000 abstract 1
- 101000585315 Homo sapiens Glutaminyl-peptide cyclotransferase Proteins 0.000 abstract 1
- 101000619665 Homo sapiens Leucine-rich repeat-containing protein 2 Proteins 0.000 abstract 1
- 101000575378 Homo sapiens Microfibrillar-associated protein 2 Proteins 0.000 abstract 1
- 102100022236 Leucine-rich repeat-containing protein 2 Human genes 0.000 abstract 1
- 102100025599 Microfibrillar-associated protein 2 Human genes 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000001441 melanoma Diseases 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Cette invention concerne des procédés et des kits utilisés pour détecter et diagnostiquer le cancer ou des états précancéreux. La méthylation de gènes spécifiques s'avère un élément indicateur du cancer, et les procédés de l'invention concernent, en partie, la détection des taux de méthylation dans les cellules utilisée comme élément de détermination du cancer ou d'un état précancéreux de la cellule.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/312,807 US20100143899A1 (en) | 2005-05-17 | 2007-11-29 | Methods and products for diagnosing cancer |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86175506P | 2006-11-29 | 2006-11-29 | |
US60/861,755 | 2006-11-29 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2008066878A2 WO2008066878A2 (fr) | 2008-06-05 |
WO2008066878A3 true WO2008066878A3 (fr) | 2008-12-11 |
WO2008066878A9 WO2008066878A9 (fr) | 2009-05-28 |
Family
ID=39468508
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2007/024553 WO2008066878A2 (fr) | 2005-05-17 | 2007-11-29 | Procédés et produits utilisés pour diagnostiquer le cancer |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2008066878A2 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008134020A1 (fr) | 2007-04-26 | 2008-11-06 | University Of Vermont And State Agricultural College | Procédés et compositions de ccl18 et ccl3 pour la détection et le traitement du cancer |
EP2238267A2 (fr) * | 2008-01-24 | 2010-10-13 | Université de Lausanne | Procédé de prédiction et de diagnostic d'une tumeur cérébrale |
CN101962684B (zh) * | 2010-11-04 | 2012-03-28 | 徐州师范大学 | 黄牛pcsk1基因的单核苷酸多态性及其检测方法 |
WO2012081017A1 (fr) | 2010-12-15 | 2012-06-21 | Yeda Research And Development Co. Ltd. | Compositions et procédés pour le traitement du cancer et de maladies neurodégénératives |
EP3037545A1 (fr) * | 2014-12-23 | 2016-06-29 | The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin | Test de méthylation d'ADN pour le cancer de la prostate |
CN112585282A (zh) * | 2018-07-26 | 2021-03-30 | 北京艾克伦医疗科技有限公司 | 鉴定乳腺癌状态的方法和试剂盒 |
CN114410792B (zh) * | 2022-02-10 | 2023-07-25 | 博尔诚(北京)科技有限公司 | 用于肾癌筛查的标志物、探针组合物及其应用 |
CN118441051B (zh) * | 2024-05-28 | 2025-05-02 | 南通大学 | 一种与肺腺癌相关的meQTL-SNPs生物标志物及其应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005095644A2 (fr) * | 2004-04-04 | 2005-10-13 | Oligene Gmbh | Procede d'identification de signatures dans des profils d'expression genetique complexes |
WO2007149269A2 (fr) * | 2006-06-12 | 2007-12-27 | Oncomethylome Sciences S.A. | Marqueurs de méthylation destinés à une détection et un pronostic précoces de cancers du côlon |
-
2007
- 2007-11-29 WO PCT/US2007/024553 patent/WO2008066878A2/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005095644A2 (fr) * | 2004-04-04 | 2005-10-13 | Oligene Gmbh | Procede d'identification de signatures dans des profils d'expression genetique complexes |
WO2007149269A2 (fr) * | 2006-06-12 | 2007-12-27 | Oncomethylome Sciences S.A. | Marqueurs de méthylation destinés à une détection et un pronostic précoces de cancers du côlon |
Non-Patent Citations (5)
Title |
---|
FURUTA JUNICHI ET AL: "Silencing of the thrombomodulin gene in human malignant melanoma", MELANOMA RESEARCH, vol. 15, no. 1, February 2005 (2005-02-01), pages 15 - 20, XP009103389, ISSN: 0960-8931 * |
GILLIS JOHN STUART: "Microarray evidence of glutaminyl cyclase gene expression in melanoma: implications for tumor antigen specific immunotherapy", JOURNAL OF TRANSLATIONAL MEDICINE, BIOMED CENTRAL, LONDON, GB, vol. 4, no. 1, 4 July 2006 (2006-07-04), pages 27, XP021018978, ISSN: 1479-5876 * |
KORABIOWSKA MONIKA ET AL: "Analysis of adenomatous polyposis coli gene expression, APC locus-microsatellite instability and APC promoter methylation in the progression of melanocytic tumours", MODERN PATHOLOGY, vol. 17, no. 12, December 2004 (2004-12-01), pages 1539 - 1544, XP002489097, ISSN: 0893-3952 * |
MIRMOHAMMADSADEGH ALIREZA ET AL: "Epigenetic silencing of the PTEN gene in melanoma.", CANCER RESEARCH 1 JUL 2006, vol. 66, no. 13, 1 July 2006 (2006-07-01), pages 6546 - 6552, XP002489096, ISSN: 0008-5472 * |
MUTHUSAMY VISWANATHAN ET AL: "Epigenetic silencing of novel tumor suppressors in malignant melanoma", CANCER RESEARCH, vol. 66, no. 23, December 2006 (2006-12-01), pages 11187 - 11193, XP002489098, ISSN: 0008-5472 * |
Also Published As
Publication number | Publication date |
---|---|
WO2008066878A9 (fr) | 2009-05-28 |
WO2008066878A2 (fr) | 2008-06-05 |
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