+

WO2007031620A3 - Mousses dermatologiques a base de metronidazole et emulsions pour leur preparation - Google Patents

Mousses dermatologiques a base de metronidazole et emulsions pour leur preparation Download PDF

Info

Publication number
WO2007031620A3
WO2007031620A3 PCT/FR2006/002037 FR2006002037W WO2007031620A3 WO 2007031620 A3 WO2007031620 A3 WO 2007031620A3 FR 2006002037 W FR2006002037 W FR 2006002037W WO 2007031620 A3 WO2007031620 A3 WO 2007031620A3
Authority
WO
WIPO (PCT)
Prior art keywords
mass
metronidazole
emulsions
production
agent
Prior art date
Application number
PCT/FR2006/002037
Other languages
English (en)
Other versions
WO2007031620A2 (fr
WO2007031620B1 (fr
Inventor
Dov Tamarkin
Doron Friedman
Original Assignee
Galderma Sa
Dov Tamarkin
Doron Friedman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Sa, Dov Tamarkin, Doron Friedman filed Critical Galderma Sa
Priority to EP06808065A priority Critical patent/EP1928416A2/fr
Publication of WO2007031620A2 publication Critical patent/WO2007031620A2/fr
Publication of WO2007031620A3 publication Critical patent/WO2007031620A3/fr
Publication of WO2007031620B1 publication Critical patent/WO2007031620B1/fr
Priority to US12/076,115 priority patent/US20090041678A1/en
Priority to US13/154,476 priority patent/US20110237637A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des émulsions comprenant, en pourcentage en masse par rapport à la masse totale de Ia composition : (a) 70% a 81 % d'eau ; (b) 0,1% a 5% d'un agent gélifiant de la phase aqueuse de l'émulsion ; (c) 0,75% a 2% de métronidazole ; (d) 4% a 10% d'huile minérale ; (e) 0,5% a 10% d'un agent tensioactif ; (f) 0,5% a 5% d'un acide gras ; (g) 0,1% a 5% d'un agent conservateur ; et (h) 0 a 5% d'un promoteur d'absorption du métronidazole. L'invention concerne également des mousses à base de métronidazole obtenues à partir de ces émulsions, ainsi que leur utilisation dermatologique.
PCT/FR2006/002037 2005-09-13 2006-09-05 Mousses dermatologiques a base de metronidazole et emulsions pour leur preparation WO2007031620A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP06808065A EP1928416A2 (fr) 2005-09-13 2006-09-05 Mousses dermatologiques a base de metronidazole et emulsions pour leur preparation
US12/076,115 US20090041678A1 (en) 2005-09-13 2008-03-13 Metronidazole-based dermatological foams and emulsions for the preparation thereof
US13/154,476 US20110237637A1 (en) 2005-09-13 2011-06-07 Metronidazole-based dermatological foam and emulsions for the production thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0509342 2005-09-13
FR0509342A FR2890560B1 (fr) 2005-09-13 2005-09-13 Mousses dermatologiques a base de metronidazole et emulsions pour leur preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/076,115 Continuation US20090041678A1 (en) 2005-09-13 2008-03-13 Metronidazole-based dermatological foams and emulsions for the preparation thereof

Publications (3)

Publication Number Publication Date
WO2007031620A2 WO2007031620A2 (fr) 2007-03-22
WO2007031620A3 true WO2007031620A3 (fr) 2007-05-03
WO2007031620B1 WO2007031620B1 (fr) 2007-06-21

Family

ID=36601229

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2006/002037 WO2007031620A2 (fr) 2005-09-13 2006-09-05 Mousses dermatologiques a base de metronidazole et emulsions pour leur preparation

Country Status (4)

Country Link
US (2) US20090041678A1 (fr)
EP (1) EP1928416A2 (fr)
FR (1) FR2890560B1 (fr)
WO (1) WO2007031620A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3054236A1 (fr) 2011-06-28 2013-01-03 Chemo Research Sl Formulations de gel a base de metronidazole aqueux mucoadhesif a dosage eleve et leur utilisation pour traiter une vaginose bacterienne
US11278025B2 (en) 2017-05-17 2022-03-22 The General Hospital Corporation Antibiotic compounds

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837378A (en) * 1986-01-15 1989-06-06 Curatek Pharmaceuticals, Inc. Topical metronidazole formulations and therapeutic uses thereof
US5536743A (en) * 1988-01-15 1996-07-16 Curatek Pharmaceuticals Limited Partnership Intravaginal treatment of vaginal infections with buffered metronidazole compositions
US6468989B1 (en) * 2000-07-13 2002-10-22 Dow Pharmaceutical Sciences Gel compositions containing metronidazole
WO2004037225A2 (fr) * 2002-10-25 2004-05-06 Foamix Ltd. Mousse cosmetique et pharmaceutique
WO2005018530A2 (fr) * 2003-08-25 2005-03-03 Foamix Ltd. Mousse pharmaceutique de penetration

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300491A (en) * 1991-10-31 1994-04-05 Apothekernes Laboratorium A.S. Treatment of protozoal infection
US20050255048A1 (en) * 2004-05-15 2005-11-17 Collegium Pharmaceutical, Inc. Sprayable formulations for the treatment of acute inflammatory skin conditions
US20060024243A1 (en) * 2004-08-02 2006-02-02 Agis Industries (1983) Ltd. Foamable compositions containing nitro-imidazoles, processes for preparing same and methods of treatment utilizing same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837378A (en) * 1986-01-15 1989-06-06 Curatek Pharmaceuticals, Inc. Topical metronidazole formulations and therapeutic uses thereof
US5536743A (en) * 1988-01-15 1996-07-16 Curatek Pharmaceuticals Limited Partnership Intravaginal treatment of vaginal infections with buffered metronidazole compositions
US6468989B1 (en) * 2000-07-13 2002-10-22 Dow Pharmaceutical Sciences Gel compositions containing metronidazole
WO2004037225A2 (fr) * 2002-10-25 2004-05-06 Foamix Ltd. Mousse cosmetique et pharmaceutique
WO2005018530A2 (fr) * 2003-08-25 2005-03-03 Foamix Ltd. Mousse pharmaceutique de penetration

Also Published As

Publication number Publication date
US20110237637A1 (en) 2011-09-29
WO2007031620A2 (fr) 2007-03-22
US20090041678A1 (en) 2009-02-12
FR2890560A1 (fr) 2007-03-16
WO2007031620B1 (fr) 2007-06-21
EP1928416A2 (fr) 2008-06-11
FR2890560B1 (fr) 2011-06-24

Similar Documents

Publication Publication Date Title
WO2007031621A3 (fr) Mousses dermatologiques a base de metronidazole et emulsions pour leur preparation
WO2007076062A3 (fr) Formulations de proteines a viscosite reduite et leurs utilisations
WO2008138894A3 (fr) Formulations de mousses exemptes d'agent tensio-actif
WO2009085889A3 (fr) Compositions et procédés pour réduire ou empêcher la perte d'eau par la peau
WO2010017108A3 (fr) Emulsions de poix
WO2008030949A3 (fr) Émulsions d'acides gras polyinsaturés stables et procédés permettant d'inhiber, de supprimer ou de réduire la dégradation des acides gras polyinsaturés dans une émulsion
EP2123257A3 (fr) Système émulsifié stable polyol dans l'huile à teneur élevée en vitamine C et sa préparation
WO2007115675A3 (fr) Liants à base de nitrocellulose destinés à des vernis à ongles aqueux
WO2010000348A8 (fr) Mousse de soins cutanés
WO2011115700A3 (fr) Mousses émollientes pour le traitement de dermatite séborrhéique
WO2006042064A3 (fr) Composition empechant la propagation du feu et favorisant l'extinction d'un feu existant, et procede de preparation et d'utilisation associes
WO2008061179A3 (fr) Dispositifs et procédés de fabrication de glace
WO2010108756A3 (fr) Compositions aqueuses pour le nettoyage des cheveux et de la peau
WO2006083630A3 (fr) Diiodomethyl-p-tolylsulfone dans un solvant liquide combine a un agent actif antipelliculaire
WO2008003538A3 (fr) Composition de confiserie glacée à faible teneur en matière grasse
WO2012035468A3 (fr) Composition topique moussante
WO2009027867A3 (fr) Compositions moussantes
WO2005058254A3 (fr) Nettoyants d'hygiene personnelle non-aqueux auto-moussants contenant peu ou pas d'agent de surface
WO2008140262A3 (fr) Utilisation d'un tensioactif biologique en tant qu'agent anti-inflammatoire et solution de conservation de tissus
ZA200900075B (en) Use of oily soft waxes as hydrophobizing agents in timber products, timber products thus produced, and processes for introducing soft waxes into timber products
WO2010052072A4 (fr) Composition
WO2006117885A8 (fr) Preparation cutanee externe
WO2008013669A3 (fr) Formulation à libération prolongée d'acide alpha hydroxy
NO20091517L (no) Emulsjon
WO2008143090A1 (fr) Composition d'émulsion de type eau dans huile

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2006808065

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE

WWP Wipo information: published in national office

Ref document number: 2006808065

Country of ref document: EP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载