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WO2008013669A3 - Formulation à libération prolongée d'acide alpha hydroxy - Google Patents

Formulation à libération prolongée d'acide alpha hydroxy Download PDF

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Publication number
WO2008013669A3
WO2008013669A3 PCT/US2007/015741 US2007015741W WO2008013669A3 WO 2008013669 A3 WO2008013669 A3 WO 2008013669A3 US 2007015741 W US2007015741 W US 2007015741W WO 2008013669 A3 WO2008013669 A3 WO 2008013669A3
Authority
WO
WIPO (PCT)
Prior art keywords
alpha hydroxy
hydroxy acid
sustained release
release formulation
acid sustained
Prior art date
Application number
PCT/US2007/015741
Other languages
English (en)
Other versions
WO2008013669A2 (fr
Inventor
Yunik Chang
Nayan Desai
Original Assignee
Dow Pharmaceutical Sciences
Yunik Chang
Nayan Desai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Pharmaceutical Sciences, Yunik Chang, Nayan Desai filed Critical Dow Pharmaceutical Sciences
Publication of WO2008013669A2 publication Critical patent/WO2008013669A2/fr
Publication of WO2008013669A3 publication Critical patent/WO2008013669A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/342—Alcohols having more than seven atoms in an unbroken chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/416—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4993—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne une émulsion huile dans eau contenant un ou plusieurs acides alpha hydroxy, la phase huileuse de l'émulsion contenant une grande proportion de constituants polaires. L'émulsion n'est pas irritante pour une application sur la peau, même à de fortes concentrations d'acide alpha hydroxy.
PCT/US2007/015741 2006-07-21 2007-07-11 Formulation à libération prolongée d'acide alpha hydroxy WO2008013669A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/490,896 US8715700B2 (en) 2006-07-21 2006-07-21 Alpha hydroxy acid sustained release formulation
US11/490,896 2006-07-21

Publications (2)

Publication Number Publication Date
WO2008013669A2 WO2008013669A2 (fr) 2008-01-31
WO2008013669A3 true WO2008013669A3 (fr) 2008-12-04

Family

ID=38971710

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/015741 WO2008013669A2 (fr) 2006-07-21 2007-07-11 Formulation à libération prolongée d'acide alpha hydroxy

Country Status (2)

Country Link
US (1) US8715700B2 (fr)
WO (1) WO2008013669A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG185567A1 (en) 2010-05-21 2012-12-28 Incyte Corp Topical formulation for a jak inhibitor
TWI789516B (zh) 2013-08-07 2023-01-11 美商英塞特公司 Jak1抑制劑之持續釋放劑型
DE202015008361U1 (de) 2014-12-03 2016-04-21 Mary Kay Inc. Kosmetische Zusammensetzungen
US9895359B1 (en) 2017-06-07 2018-02-20 Arcutis, Inc. Inhibition of crystal growth of roflumilast
US11129818B2 (en) 2017-06-07 2021-09-28 Arcutis Biotherapeutics, Inc. Topical roflumilast formulation having improved delivery and plasma half life
US11554086B2 (en) 2017-12-29 2023-01-17 L'oreal Cosmetic composition comprising glycolic acid and methods of use
CA3102689C (fr) 2018-06-04 2023-08-29 Arcutis, Inc. Methode et formulation pour ameliorer le temps de latence de penetration de la peau du roflumilast
AU2021268977B2 (en) * 2020-05-07 2024-05-23 Arcutis Biotherapeutics, Inc. Treatment of skin conditions using high Krafft temperature anionic surfactants

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709663B2 (en) * 2001-08-31 2004-03-23 Healthpoint, Ltd. Multivesicular emulsion drug delivery systems

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5407958A (en) 1993-07-30 1995-04-18 Beauticontrol Cosmetics, Inc. Therapeutic skin composition
FR2718022B1 (fr) 1994-04-01 1996-04-26 Roussel Uclaf Compositions cosmétiques ou dermatologiques et leur préparation.
DE4442966A1 (de) 1994-12-02 1996-06-05 Henkel Kgaa Wasser-in-Öl-Emulsionen
US5804203A (en) 1994-12-21 1998-09-08 Cosmederm Technologies Topical product formulations containing strontium for reducing skin irritation
CA2213517C (fr) 1995-02-22 2002-01-22 Bausch & Lomb, Incorporated Composition de soins de la peau
GB9612067D0 (en) 1996-06-10 1996-08-14 Smithkline Beecham Plc Composition
US5817155A (en) 1996-08-08 1998-10-06 Shiseido Co., Ltd. Emulsion for hair treatment
DE19801593A1 (de) 1998-01-17 1999-07-22 Henkel Kgaa Lipoprotein-Cremes
FR2817739B1 (fr) 2000-12-12 2005-01-07 Oreal Composition cosmetique coloree transparente ou translucide
US20030017181A1 (en) 2001-05-31 2003-01-23 Rood Gloria A. Dermatological compositions and methods
DE10141474A1 (de) 2001-08-29 2003-03-20 Beiersdorf Ag Stabilisierung UV-empfindlicher Wirkstoffe

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709663B2 (en) * 2001-08-31 2004-03-23 Healthpoint, Ltd. Multivesicular emulsion drug delivery systems

Also Published As

Publication number Publication date
US8715700B2 (en) 2014-05-06
WO2008013669A2 (fr) 2008-01-31
US20080020005A1 (en) 2008-01-24

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