WO2007007014A3 - Nouveau procede de preparation de nanoparticules de chitine - Google Patents
Nouveau procede de preparation de nanoparticules de chitine Download PDFInfo
- Publication number
- WO2007007014A3 WO2007007014A3 PCT/FR2006/050712 FR2006050712W WO2007007014A3 WO 2007007014 A3 WO2007007014 A3 WO 2007007014A3 FR 2006050712 W FR2006050712 W FR 2006050712W WO 2007007014 A3 WO2007007014 A3 WO 2007007014A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- less
- novel method
- preparing chitin
- chitin nanoparticles
- concentration
- Prior art date
Links
- 229920002101 Chitin Polymers 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000002105 nanoparticle Substances 0.000 title abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 abstract 1
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 abstract 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 abstract 1
- 230000021736 acetylation Effects 0.000 abstract 1
- 238000006640 acetylation reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 abstract 1
- 229960002442 glucosamine Drugs 0.000 abstract 1
- 229950006780 n-acetylglucosamine Drugs 0.000 abstract 1
- 238000006116 polymerization reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
- C08J3/14—Powdering or granulating by precipitation from solutions
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
- C08J2305/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
Procédé de préparation de nanoparticules de chitine dans lequel des chaînes copolymère de glucosamine et de N-acétyl-D-glucosamine liés par une liaison β,(l→4), qui présentent un degré moyen d'acétylation DA supérieur ou égal à 50 % et un degré de polymérisation moyen en poids DPW supérieur ou égal à 1500, sont dispersées à une concentration C au moins égale à la concentration C* d'enchevêtrement des chaînes copolymères, dans une solution aqueuse dont le pH est compris entre 1 et 8, la dite solution étant obtenue par mélange en solution aqueuse d'un acide et d'un sel.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0507439 | 2005-07-12 | ||
FR0507439A FR2888581B1 (fr) | 2005-07-12 | 2005-07-12 | Nouveau procede de preparation de nanoparticules de chitine |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007007014A2 WO2007007014A2 (fr) | 2007-01-18 |
WO2007007014A3 true WO2007007014A3 (fr) | 2007-04-26 |
Family
ID=36602579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/FR2006/050712 WO2007007014A2 (fr) | 2005-07-12 | 2006-07-12 | Nouveau procede de preparation de nanoparticules de chitine |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2888581B1 (fr) |
WO (1) | WO2007007014A2 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3016882A1 (fr) | 2014-01-30 | 2015-07-31 | Sofradim Production | Procede de preparation de chitosane a haut degre d’acetylation |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001032751A1 (fr) * | 1999-10-29 | 2001-05-10 | Cognis Deutschland Gmbh & Co. Kg | Procede de preparation de chitosanes ou de derives de chitosane nanoparticulaires |
US20040176477A1 (en) * | 2003-03-06 | 2004-09-09 | The Procter & Gamble Company | Chitosan powder |
-
2005
- 2005-07-12 FR FR0507439A patent/FR2888581B1/fr not_active Expired - Fee Related
-
2006
- 2006-07-12 WO PCT/FR2006/050712 patent/WO2007007014A2/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001032751A1 (fr) * | 1999-10-29 | 2001-05-10 | Cognis Deutschland Gmbh & Co. Kg | Procede de preparation de chitosanes ou de derives de chitosane nanoparticulaires |
US20040176477A1 (en) * | 2003-03-06 | 2004-09-09 | The Procter & Gamble Company | Chitosan powder |
Non-Patent Citations (6)
Title |
---|
C. SCHATZ, C. PICHOT, T. DELAIR, C. VITON, A. DOMARD: "Static light scattering studies on chitosan solutions: from macromolecular chains to colloidal dispersions", LANGMUIR, vol. 19, 2003, pages 9896 - 9903, XP002389209 * |
CALVO P ET AL: "Chitosan and chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines", PHARMACEUTICAL RESEARCH, NEW YORK, NY, US, vol. 14, no. 10, October 1997 (1997-10-01), pages 1431 - 1436, XP002082343, ISSN: 0724-8741 * |
G. LAMARQUE, J.-M. LUCAS, C. VITON, A. DOMARD: "Physicochemical behavior of homogeneous series of acetylated chitosans in aqueous solution: role of various structural parameters", BIOMACROMOLECULES, vol. 6, 2005, pages 131 - 142, XP002389210 * |
MONTEMBAULT A ET AL: "Physico-chemical studies of the gelation of chitosan in a hydroalcoholic medium", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 26, no. 8, March 2005 (2005-03-01), pages 933 - 943, XP004558455, ISSN: 0142-9612 * |
T. BANERJEE, S. MITRA, A.K.SINGH, R.K. SHARMA, A. MAITRA: "preparation, characterisation and biodistribution of ultrafine chitosan nanoparticles", INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 243, 2002, pages 93 - 105, XP002389212 * |
YONGMEI XU, YUMIN DU: "Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles", INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 250, 2003, pages 215 - 226, XP002389211 * |
Also Published As
Publication number | Publication date |
---|---|
FR2888581A1 (fr) | 2007-01-19 |
FR2888581B1 (fr) | 2010-05-14 |
WO2007007014A2 (fr) | 2007-01-18 |
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