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WO2006021874A3 - Nouvelles sequences de nucleotides et d'acides amines; essais et methodes d'utilisation pour le diagnostic du cancer de a la prostate - Google Patents

Nouvelles sequences de nucleotides et d'acides amines; essais et methodes d'utilisation pour le diagnostic du cancer de a la prostate Download PDF

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Publication number
WO2006021874A3
WO2006021874A3 PCT/IB2005/002560 IB2005002560W WO2006021874A3 WO 2006021874 A3 WO2006021874 A3 WO 2006021874A3 IB 2005002560 W IB2005002560 W IB 2005002560W WO 2006021874 A3 WO2006021874 A3 WO 2006021874A3
Authority
WO
WIPO (PCT)
Prior art keywords
prostate cancer
markers
diagnosis
assays
methods
Prior art date
Application number
PCT/IB2005/002560
Other languages
English (en)
Other versions
WO2006021874A2 (fr
WO2006021874A8 (fr
Inventor
Dvir Dahary
Sarah Pollock
Zurit Levine
Rotem Sorek
Michal Ayalon-Soffer
Pinchas Akiva
Amir Toporik
Osnat Sella-Tavor
Shirley Sameah-Greenwald
Original Assignee
Compugen Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compugen Usa Inc filed Critical Compugen Usa Inc
Priority to CA002554707A priority Critical patent/CA2554707A1/fr
Priority to EP05805032A priority patent/EP1735468A2/fr
Priority claimed from US11/043,806 external-priority patent/US7368548B2/en
Publication of WO2006021874A2 publication Critical patent/WO2006021874A2/fr
Publication of WO2006021874A8 publication Critical patent/WO2006021874A8/fr
Publication of WO2006021874A3 publication Critical patent/WO2006021874A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Cette invention concerne des nouveaux marqueurs pour le cancer de la prostate qui sont à la fois sensibles et précis. De plus, ces marqueurs sont capables de distinguer un cancer de la prostate d'une hyperplasie prostatique bénigne. Lesdits marqueurs sont surexprimés spécifiquement dans le cancer de la prostates par opposition à des tissus prostatiques normaux et/ou une hyperplasie prostatique bénigne. La mesure de ces marqueurs, seuls ou en combinaison, dans des échantillons prélevés sur un patient donne des informations que le diagnosticien peut corréler avec un diagnostic probable de cancer de la prostate. Les marqueurs de la présente invention, seuls ou en combinaison, autorisent une détection différentielle poussée entre le cancer de la prostate et des états non cancéreux.
PCT/IB2005/002560 2004-01-27 2005-01-27 Nouvelles sequences de nucleotides et d'acides amines; essais et methodes d'utilisation pour le diagnostic du cancer de a la prostate WO2006021874A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002554707A CA2554707A1 (fr) 2004-01-27 2005-01-27 Nouvelles sequences de nucleotides et d'acides amines; essais et methodes d'utilisation pour le diagnostic du cancer de a la prostate
EP05805032A EP1735468A2 (fr) 2004-01-27 2005-01-27 Nouvelles sequences de nucleotides et d'acides amines; essais et methodes d'utilisation pour le diagnostic du cancer de a la prostate

Applications Claiming Priority (46)

Application Number Priority Date Filing Date Title
US53912804P 2004-01-27 2004-01-27
US53912904P 2004-01-27 2004-01-27
US60/539,129 2004-01-27
US60/539,128 2004-01-27
US58416604P 2004-07-01 2004-07-01
US60/584,166 2004-07-01
US60725904P 2004-09-07 2004-09-07
US60/607,259 2004-09-07
US62085304P 2004-10-22 2004-10-22
US62065604P 2004-10-22 2004-10-22
US62087404P 2004-10-22 2004-10-22
US62067704P 2004-10-22 2004-10-22
US62091604P 2004-10-22 2004-10-22
US62091804P 2004-10-22 2004-10-22
US60/620,916 2004-10-22
US60/620,677 2004-10-22
US60/620,874 2004-10-22
US60/620,656 2004-10-22
US60/620,918 2004-10-22
US60/620,853 2004-10-22
US62113104P 2004-10-25 2004-10-25
US60/621,131 2004-10-25
US62814504P 2004-11-17 2004-11-17
US62810104P 2004-11-17 2004-11-17
US62825104P 2004-11-17 2004-11-17
US62823104P 2004-11-17 2004-11-17
US62812304P 2004-11-17 2004-11-17
US62815604P 2004-11-17 2004-11-17
US62813404P 2004-11-17 2004-11-17
US62811204P 2004-11-17 2004-11-17
US62811104P 2004-11-17 2004-11-17
US62816704P 2004-11-17 2004-11-17
US62817804P 2004-11-17 2004-11-17
US60/628,134 2004-11-17
US60/628,123 2004-11-17
US60/628,231 2004-11-17
US60/628,178 2004-11-17
US60/628,167 2004-11-17
US60/628,251 2004-11-17
US60/628,101 2004-11-17
US60/628,112 2004-11-17
US60/628,156 2004-11-17
US60/628,145 2004-11-17
US11/043,806 US7368548B2 (en) 2004-01-27 2005-01-27 Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of prostate cancer
US- 2005-01-27
US11/043,806 2005-01-27

Publications (3)

Publication Number Publication Date
WO2006021874A2 WO2006021874A2 (fr) 2006-03-02
WO2006021874A8 WO2006021874A8 (fr) 2007-03-15
WO2006021874A3 true WO2006021874A3 (fr) 2009-04-09

Family

ID=35967908

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/002560 WO2006021874A2 (fr) 2004-01-27 2005-01-27 Nouvelles sequences de nucleotides et d'acides amines; essais et methodes d'utilisation pour le diagnostic du cancer de a la prostate

Country Status (1)

Country Link
WO (1) WO2006021874A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108997498A (zh) 2008-12-09 2018-12-14 霍夫曼-拉罗奇有限公司 抗-pd-l1抗体及它们用于增强t细胞功能的用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902921A (en) * 1997-01-31 1999-05-11 Pioneer Hi-Bred International, Inc. Hybrid maize plant and seed (34K77)
WO2003105758A2 (fr) * 2002-06-12 2003-12-24 Avalon Pharmaceuticals, Inc. Gene lie au cancer utilise comme cible pour la chimiotherapie
US20040229277A1 (en) * 2001-09-18 2004-11-18 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902921A (en) * 1997-01-31 1999-05-11 Pioneer Hi-Bred International, Inc. Hybrid maize plant and seed (34K77)
US20040229277A1 (en) * 2001-09-18 2004-11-18 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
WO2003105758A2 (fr) * 2002-06-12 2003-12-24 Avalon Pharmaceuticals, Inc. Gene lie au cancer utilise comme cible pour la chimiotherapie

Also Published As

Publication number Publication date
WO2006021874A2 (fr) 2006-03-02
WO2006021874A8 (fr) 2007-03-15

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