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WO2006012627A3 - Polypeptides du recepteur actrii, procedes et compositions correspondants - Google Patents

Polypeptides du recepteur actrii, procedes et compositions correspondants Download PDF

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Publication number
WO2006012627A3
WO2006012627A3 PCT/US2005/026368 US2005026368W WO2006012627A3 WO 2006012627 A3 WO2006012627 A3 WO 2006012627A3 US 2005026368 W US2005026368 W US 2005026368W WO 2006012627 A3 WO2006012627 A3 WO 2006012627A3
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WO
WIPO (PCT)
Prior art keywords
methods
compositions
actrii
receptor polypeptides
actrii receptor
Prior art date
Application number
PCT/US2005/026368
Other languages
English (en)
Other versions
WO2006012627A2 (fr
Inventor
John Knopf
Jasbir Seehra
Original Assignee
Acceleron Pharma Inc
John Knopf
Jasbir Seehra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acceleron Pharma Inc, John Knopf, Jasbir Seehra filed Critical Acceleron Pharma Inc
Priority to ES05775451T priority Critical patent/ES2426005T3/es
Priority to AU2005266875A priority patent/AU2005266875B2/en
Priority to EP18197548.3A priority patent/EP3489257A1/fr
Priority to CA2574777A priority patent/CA2574777C/fr
Priority to EP15196071.3A priority patent/EP3059245B1/fr
Priority to EP05775451.7A priority patent/EP1771470B1/fr
Priority to JP2007522846A priority patent/JP2008507288A/ja
Publication of WO2006012627A2 publication Critical patent/WO2006012627A2/fr
Publication of WO2006012627A3 publication Critical patent/WO2006012627A3/fr

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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
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    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/1103—Receptor protein serine/threonine kinase (2.7.11.30)

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Abstract

Dans certains aspects, l'invention concerne des compositions et de procédés permettant de moduler (favoriser ou inhiber) la croissance d'un tissu, comme un os, un cartilage, un muscle, une graisse et/ou un neurone. L'invention concerne également des procédés de criblage de composés modulant l'activité d'une protéine ActRII et/ou d'un ligand ActRII. Lesdites compositions et lesdits procédés s'utilisent dans le traitement de maladies associées à une activité anormale d'une protéine ActRII et/ou d'un ligand ActRII.
PCT/US2005/026368 2004-07-23 2005-07-25 Polypeptides du recepteur actrii, procedes et compositions correspondants WO2006012627A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ES05775451T ES2426005T3 (es) 2004-07-23 2005-07-25 Polipéptidos del receptor ACTRII, procedimientos y composiciones
AU2005266875A AU2005266875B2 (en) 2004-07-23 2005-07-25 ActRII receptor polypeptides, methods and compositions
EP18197548.3A EP3489257A1 (fr) 2004-07-23 2005-07-25 Polypeptides du récepteur actrii, procédés et compositions
CA2574777A CA2574777C (fr) 2004-07-23 2005-07-25 Polypeptides du recepteur actrii, procedes et compositions correspondants
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