WO2004060267A3 - Procede de production de fractions enrichies contenant jusqu'a 100 % de bacoside a et de bacoside b a partir de substances vegetales de l'espece bacopa - Google Patents
Procede de production de fractions enrichies contenant jusqu'a 100 % de bacoside a et de bacoside b a partir de substances vegetales de l'espece bacopa Download PDFInfo
- Publication number
- WO2004060267A3 WO2004060267A3 PCT/IN2003/000002 IN0300002W WO2004060267A3 WO 2004060267 A3 WO2004060267 A3 WO 2004060267A3 IN 0300002 W IN0300002 W IN 0300002W WO 2004060267 A3 WO2004060267 A3 WO 2004060267A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bacoside
- therefrom
- fractions containing
- washed
- solvent
- Prior art date
Links
- 229930193652 Bacoside Natural products 0.000 title abstract 3
- LKCTWIIDXXXXAR-CYGHALRTSA-N Bacoside a Chemical compound CC(C)=CCC[C@](C)(O)[C@@H]1[C@H]2CC[C@H]3[C@@](C)(CC[C@H]4C(C)(C)C(CC[C@]34CO)O[C@@H]3O[C@H](CO)[C@@H](O[C@@H]4OC[C@H](O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@]2(C)CC1=O LKCTWIIDXXXXAR-CYGHALRTSA-N 0.000 title abstract 2
- 239000000463 material Substances 0.000 abstract 3
- GKLLCNWAEBKYGL-UHFFFAOYSA-N Bacoside B Natural products CC(=CCC(C)(O)C1C2CCC3C(C)(CCC4C(C)(C)C(CCC34CO)OC5C(O)C(O)C(OCC6OCC(O)C(O)C6O)OC5CO)C2(C)CC1=O)C GKLLCNWAEBKYGL-UHFFFAOYSA-N 0.000 abstract 2
- 241000196324 Embryophyta Species 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 240000002999 Bacopa monnieri Species 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 238000013375 chromatographic separation Methods 0.000 abstract 1
- 238000011097 chromatography purification Methods 0.000 abstract 1
- 239000000356 contaminant Substances 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000003495 polar organic solvent Substances 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000003809 water extraction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
L'invention concerne un procédé de production de fractions contenant Bacosides A et B à partir de substances végétales de l'espèce Bacopa, par extraction, concentration et séparation. Selon ce procédé, lesdites substances végétales séchées sont soumises à une extraction alcoolique, hydroalcoolique ou aqueuse, et un concentré est produit à partir de l'extrait obtenu. La masse solide ainsi produite est lavée au moyen d'un solvant organique non polaire pour supprimer les matières grasses qu'elle renferme, puis soumise à une extraction à l'aide d'un solvant polaire organique. L'extrait obtenu au moyen dudit solvant est lavé pour supprimer les impuretés hydrosolubles qu'il contient, puis séché sous vide. La fraction obtenue, qui est enrichie en Bacosides A et B, est soumise de manière répétée à une séparation chromatographique et à une purification pour obtenir Bacoside A et Bacoside B.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003201756A AU2003201756A1 (en) | 2003-01-03 | 2003-01-03 | A process for producing enriched fractions containing up to 100% of bacoside a and bacoside b |
| PCT/IN2003/000002 WO2004060267A2 (fr) | 2003-01-03 | 2003-01-03 | Procede de production de fractions enrichies contenant jusqu'a 100 % de bacoside a et de bacoside b a partir de substances vegetales de l'espece bacopa |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2003/000002 WO2004060267A2 (fr) | 2003-01-03 | 2003-01-03 | Procede de production de fractions enrichies contenant jusqu'a 100 % de bacoside a et de bacoside b a partir de substances vegetales de l'espece bacopa |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2004060267A2 WO2004060267A2 (fr) | 2004-07-22 |
| WO2004060267A3 true WO2004060267A3 (fr) | 2004-11-04 |
Family
ID=32697207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IN2003/000002 WO2004060267A2 (fr) | 2003-01-03 | 2003-01-03 | Procede de production de fractions enrichies contenant jusqu'a 100 % de bacoside a et de bacoside b a partir de substances vegetales de l'espece bacopa |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2003201756A1 (fr) |
| WO (1) | WO2004060267A2 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1833692B (zh) * | 2005-03-15 | 2010-08-11 | 成都华高药业有限公司 | 一种假马齿苋提取物及其制备方法和用途 |
| US8541381B2 (en) | 2005-05-03 | 2013-09-24 | Laila Impex | Process for producing enriched fractions containing up to 100% of bacopasaponins from the plant materials of bacopa species |
| CN111067965B (zh) * | 2019-12-29 | 2021-10-01 | 三原润禾生物科技有限公司 | 一种假马齿苋皂甙的制备方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999040897A1 (fr) * | 1998-02-12 | 1999-08-19 | Sederma S.A. | Compositions a usage cosmetiques ou dermopharmaceutique contenant un extrait vegetal obtenu a partir de bacopa monnieri (l.) |
| US6361804B2 (en) * | 1996-12-28 | 2002-03-26 | Shyam B. Singh-Verma | Cosmetic formulations containing extracts from Phyllanthus emblica and Centella asiatica and/or Bacopa monnieri |
-
2003
- 2003-01-03 WO PCT/IN2003/000002 patent/WO2004060267A2/fr not_active Application Discontinuation
- 2003-01-03 AU AU2003201756A patent/AU2003201756A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6361804B2 (en) * | 1996-12-28 | 2002-03-26 | Shyam B. Singh-Verma | Cosmetic formulations containing extracts from Phyllanthus emblica and Centella asiatica and/or Bacopa monnieri |
| WO1999040897A1 (fr) * | 1998-02-12 | 1999-08-19 | Sederma S.A. | Compositions a usage cosmetiques ou dermopharmaceutique contenant un extrait vegetal obtenu a partir de bacopa monnieri (l.) |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003201756A8 (en) | 2004-07-29 |
| AU2003201756A1 (en) | 2004-07-29 |
| WO2004060267A2 (fr) | 2004-07-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY141766A (en) | Extraction process for removal of impurities from an aqueous mixture | |
| CA2563487A1 (fr) | Procedes pour preparer des extraits de matieres vegetales et compositions alimentaires pour animaux domestiques | |
| ZA922769B (en) | Methods and compositions for isolating taxanes | |
| CA2524714A1 (fr) | Procede de production de tabac regenere | |
| DE60001173D1 (de) | Verfahren zum extrahieren und reinigung von paclitaxel aus natürlicher quelle | |
| ATE353699T1 (de) | Verfahren zur extraktion und analyse von inhaltsstoffen aus organischem material | |
| HK1087109A1 (en) | Process for isolation and purification of paclitaxel from natural sources | |
| CA2563483A1 (fr) | Elimination de composes azotes du tabac | |
| WO2008071985A3 (fr) | Procédé d'extraction et procédé de purification | |
| WO2005046829B1 (fr) | Séparation des gingolides d'avec le g.biloba | |
| ATE395408T1 (de) | Verfahren zur gewinnung eines traubentannin, erhaltenes tannin und verwendungen | |
| ATE429411T1 (de) | Verfahren zur isolierung phenolischer substanzen bzw. juvabionen aus knöterich enthaltendem holz | |
| WO2004060267A3 (fr) | Procede de production de fractions enrichies contenant jusqu'a 100 % de bacoside a et de bacoside b a partir de substances vegetales de l'espece bacopa | |
| ATE285826T1 (de) | Lösungsmittelextraktionsverfahren | |
| ATE240926T1 (de) | Verfahren zur trennung und reinigung eines wässrigen gemisches aus den hauptkomponenten essigsäure und ameisensäure | |
| EP0969079A4 (fr) | Huile de malt d'orge contenant des substances vegetales associees a des ceramides, et procede de fabrication associe | |
| RU2002119475A (ru) | Способ получения антоцианового красителя из цветочного сырья | |
| GB2237805A (en) | Diketone extraction | |
| ATE481002T1 (de) | Herstellung von rauchextrakt | |
| Prapakornwiriya et al. | Recovery of sinapic acid from a waste stream in the processing of yellow mustard protein isolate | |
| DE60213447D1 (de) | Verfahren zur herstellung einer phenolischen substanz aus holz | |
| WO2010025939A3 (fr) | Procédé de préparation d'un extrait de matière végétale du type rumex acetosa l. | |
| DE602004008903D1 (de) | Verfahren zur Gewinnung von Paclitaxel aus Taxuspflanzen | |
| Martin et al. | Methods for isolating polyhydroxyalkanoates from plants | |
| ATE375191T1 (de) | Verfahren zur gewinnung einer ölfraktion und einer eiweiss-fraktion aus einer pflanzlichen ausgangssubstanz |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW |
|
| AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
| WWE | Wipo information: entry into national phase |
Ref document number: 10516107 Country of ref document: US |
|
| WWE | Wipo information: entry into national phase |
Ref document number: 1477/CHENP/2005 Country of ref document: IN |
|
| 122 | Ep: pct application non-entry in european phase | ||
| NENP | Non-entry into the national phase |
Ref country code: JP |
|
| WWW | Wipo information: withdrawn in national office |
Ref document number: JP |