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WO2003016493A3 - Transporters and ion channels - Google Patents

Transporters and ion channels Download PDF

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Publication number
WO2003016493A3
WO2003016493A3 PCT/US2002/026323 US0226323W WO03016493A3 WO 2003016493 A3 WO2003016493 A3 WO 2003016493A3 US 0226323 W US0226323 W US 0226323W WO 03016493 A3 WO03016493 A3 WO 03016493A3
Authority
WO
WIPO (PCT)
Prior art keywords
trich
ion channels
transporters
polynucleotides
agonists
Prior art date
Application number
PCT/US2002/026323
Other languages
French (fr)
Other versions
WO2003016493A2 (en
Inventor
Y Tom Tang
Preeti G Lal
Henry Yue
Mariah R Baughn
Danniel B Nguyen
Monique G Yao
Barrie D Bell
Mark L Borowsky
Sally Lee
Brooke M Emerling
Yuming Xu
Shanya D Becha
Ann E Gorvad
Yalda Azimzai
Huibin Yue
Vicki S Elliott
Ernestine A Lee
Junming Yang
Patricia M Lehr-Mason
Jayalaxmi Ramkumar
Soo Yeun Lee
Mary Faris
Christopher Turner
Michael Furness
Jenny L Buchbinder
Narinder K Chawla
Joana X Li
Ian J Forsythe
Jennifer A Griffin
Kimberly J Gietzen
Anita Swarnakar
April J A Hafalia
Erika A Lindquist
Xin Jiang
Alan A Jackson
Amy D Wilson
Pei Jin
Reena Khare
Joseph P Marquis
Original Assignee
Incyte Genomics Inc
Y Tom Tang
Preeti G Lal
Henry Yue
Mariah R Baughn
Danniel B Nguyen
Monique G Yao
Barrie D Bell
Mark L Borowsky
Sally Lee
Brooke M Emerling
Yuming Xu
Shanya D Becha
Ann E Gorvad
Yalda Azimzai
Huibin Yue
Vicki S Elliott
Ernestine A Lee
Junming Yang
Patricia M Lehr-Mason
Jayalaxmi Ramkumar
Soo Yeun Lee
Mary Faris
Christopher Turner
Michael Furness
Jenny L Buchbinder
Narinder K Chawla
Joana X Li
Ian J Forsythe
Jennifer A Griffin
Kimberly J Gietzen
Anita Swarnakar
April J A Hafalia
Erika A Lindquist
Xin Jiang
Alan A Jackson
Amy D Wilson
Pei Jin
Reena Khare
Joseph P Marquis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Y Tom Tang, Preeti G Lal, Henry Yue, Mariah R Baughn, Danniel B Nguyen, Monique G Yao, Barrie D Bell, Mark L Borowsky, Sally Lee, Brooke M Emerling, Yuming Xu, Shanya D Becha, Ann E Gorvad, Yalda Azimzai, Huibin Yue, Vicki S Elliott, Ernestine A Lee, Junming Yang, Patricia M Lehr-Mason, Jayalaxmi Ramkumar, Soo Yeun Lee, Mary Faris, Christopher Turner, Michael Furness, Jenny L Buchbinder, Narinder K Chawla, Joana X Li, Ian J Forsythe, Jennifer A Griffin, Kimberly J Gietzen, Anita Swarnakar, April J A Hafalia, Erika A Lindquist, Xin Jiang, Alan A Jackson, Amy D Wilson, Pei Jin, Reena Khare, Joseph P Marquis filed Critical Incyte Genomics Inc
Priority to AU2002332573A priority Critical patent/AU2002332573A1/en
Priority to CA002458625A priority patent/CA2458625A1/en
Priority to JP2003521802A priority patent/JP2005503790A/en
Publication of WO2003016493A2 publication Critical patent/WO2003016493A2/en
Publication of WO2003016493A3 publication Critical patent/WO2003016493A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Various embodiments of the invention provide human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
PCT/US2002/026323 2001-08-17 2002-08-16 Transporters and ion channels WO2003016493A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2002332573A AU2002332573A1 (en) 2001-08-17 2002-08-16 Transporters and ion channels
CA002458625A CA2458625A1 (en) 2001-08-17 2002-08-16 Transporters and ion channels
JP2003521802A JP2005503790A (en) 2001-08-17 2002-08-16 Transporters and ion channels

Applications Claiming Priority (20)

Application Number Priority Date Filing Date Title
US31324201P 2001-08-17 2001-08-17
US60/313,242 2001-08-17
US32478201P 2001-09-21 2001-09-21
US60/324,782 2001-09-21
US32818401P 2001-10-02 2001-10-02
US60/328,184 2001-10-02
US34593701P 2001-10-26 2001-10-26
US60/345,937 2001-10-26
US33569801P 2001-11-01 2001-11-01
US60/335,698 2001-11-01
US33280401P 2001-11-13 2001-11-13
US60/332,804 2001-11-13
US33392201P 2001-11-27 2001-11-27
US60/333,922 2001-11-27
US37563702P 2002-04-26 2002-04-26
US60/375,637 2002-04-26
US37744402P 2002-05-03 2002-05-03
US60/377,444 2002-05-03
US38818002P 2002-06-11 2002-06-11
US60/388,180 2002-06-11

Publications (2)

Publication Number Publication Date
WO2003016493A2 WO2003016493A2 (en) 2003-02-27
WO2003016493A3 true WO2003016493A3 (en) 2006-01-05

Family

ID=27581229

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/026323 WO2003016493A2 (en) 2001-08-17 2002-08-16 Transporters and ion channels

Country Status (4)

Country Link
JP (1) JP2005503790A (en)
AU (1) AU2002332573A1 (en)
CA (1) CA2458625A1 (en)
WO (1) WO2003016493A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040253597A1 (en) * 2001-09-17 2004-12-16 Atsushi Nakanishi Novel protein and dna thereof
AU2003216375A1 (en) * 2002-02-28 2003-09-16 Immunex Corporation Rank-ligand-induced sodium/proton antiporter polypeptides
WO2005097822A1 (en) * 2004-04-09 2005-10-20 University Of Manitoba Identification of the precise amino acid sequence of the epitope recognized by the potent neutralizing human anti-hiv-1 monoclonal antibody igg1b12
US20070180545A1 (en) * 2006-01-19 2007-08-02 Daniel Chelsky TAT-031 and methods of assessing and treating cancer
WO2012091138A1 (en) 2010-12-28 2012-07-05 大日本住友製薬株式会社 Diagnostic drug and diagnostic method for alzheimer's disease
WO2019046233A1 (en) * 2017-08-30 2019-03-07 Bristol-Myers Squibb Company A method to monitor pharmacodynamic responses mediated by in vivo administration of glucocorticoids

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001034804A1 (en) * 1999-11-12 2001-05-17 Lexicon Genetics Incorporated Human membrane proteins and polynucleotides encoding the same

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001034804A1 (en) * 1999-11-12 2001-05-17 Lexicon Genetics Incorporated Human membrane proteins and polynucleotides encoding the same

Also Published As

Publication number Publication date
AU2002332573A8 (en) 2006-11-02
JP2005503790A (en) 2005-02-10
WO2003016493A2 (en) 2003-02-27
CA2458625A1 (en) 2003-02-27
AU2002332573A1 (en) 2003-03-03

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