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WO2003001178A3 - Jeu ordonne tridimensionnel dynamique de sondes - Google Patents

Jeu ordonne tridimensionnel dynamique de sondes Download PDF

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Publication number
WO2003001178A3
WO2003001178A3 PCT/US2002/011586 US0211586W WO03001178A3 WO 2003001178 A3 WO2003001178 A3 WO 2003001178A3 US 0211586 W US0211586 W US 0211586W WO 03001178 A3 WO03001178 A3 WO 03001178A3
Authority
WO
WIPO (PCT)
Prior art keywords
array
probes
dimensional array
configurable dynamic
dynamic
Prior art date
Application number
PCT/US2002/011586
Other languages
English (en)
Other versions
WO2003001178A2 (fr
Inventor
Lewis Gruber
David Grier
Ward Lopes
Original Assignee
Arryx Inc
Lewis Gruber
David Grier
Ward Lopes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arryx Inc, Lewis Gruber, David Grier, Ward Lopes filed Critical Arryx Inc
Priority to NZ530239A priority Critical patent/NZ530239A/en
Priority to JP2003507524A priority patent/JP4199107B2/ja
Priority to CA002451222A priority patent/CA2451222A1/fr
Priority to EP02731351A priority patent/EP1412519A4/fr
Publication of WO2003001178A2 publication Critical patent/WO2003001178A2/fr
Publication of WO2003001178A3 publication Critical patent/WO2003001178A3/fr
Priority to US10/735,395 priority patent/US20040180363A1/en

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251—Colorimeters; Construction thereof
    • G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00281—Individual reactor vessels
    • B01J2219/00283—Reactor vessels with top opening
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00436—Maskless processes
    • B01J2219/00441—Maskless processes using lasers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572—Chemical means
    • B01J2219/00576—Chemical means fluorophore
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00599—Solution-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00664—Three-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00709—Type of synthesis
    • B01J2219/00711—Light-directed synthesis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0454—Moving fluids with specific forces or mechanical means specific forces radiation pressure, optical tweezers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/08—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Clinical Laboratory Science (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Composite Materials (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Fluid Mechanics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

De façon générale, la présente invention concerne un jeu ordonné de sondes pour l'analyse de cibles à l'intérieur d'un fluide. Les sondes sont logées dans des pièges optiques qui permettent de modifier la sélection ainsi que la quantité ou la qualité desdites sondes. Par ailleurs, ce jeu ordonné est dynamique dans la mesure où il est possible de repositionner un piège optique donné et la sonde qu'il contient un fois les pièges optiques configurés.
PCT/US2002/011586 2001-06-20 2002-04-12 Jeu ordonne tridimensionnel dynamique de sondes WO2003001178A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
NZ530239A NZ530239A (en) 2001-06-20 2002-04-12 Configurable dynamic three dimensional array
JP2003507524A JP4199107B2 (ja) 2001-06-20 2002-04-12 配列可能な動的３次元アレイ
CA002451222A CA2451222A1 (fr) 2001-06-20 2002-04-12 Jeu ordonne tridimensionnel dynamique de sondes
EP02731351A EP1412519A4 (fr) 2001-06-20 2002-04-12 Jeu ordonne tridimensionnel dynamique de sondes
US10/735,395 US20040180363A1 (en) 2002-04-12 2003-12-12 Configurable dynamic three dimensional array

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88680201A 2001-06-20 2001-06-20
US09/886,802 2001-06-20

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/735,395 Continuation-In-Part US20040180363A1 (en) 2002-04-12 2003-12-12 Configurable dynamic three dimensional array

Publications (2)

Publication Number Publication Date
WO2003001178A2 WO2003001178A2 (fr) 2003-01-03
WO2003001178A3 true WO2003001178A3 (fr) 2003-02-27

Family

ID=25389806

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/011586 WO2003001178A2 (fr) 2001-06-20 2002-04-12 Jeu ordonne tridimensionnel dynamique de sondes

Country Status (7)

Country Link
EP (1) EP1412519A4 (fr)
JP (1) JP4199107B2 (fr)
CN (2) CN1715918B (fr)
CA (1) CA2451222A1 (fr)
HK (1) HK1078933A1 (fr)
NZ (1) NZ530239A (fr)
WO (1) WO2003001178A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE20306138U1 (de) 2003-04-16 2003-09-04 Monajembashi, Shamci, Dr., 69126 Heidelberg Präparat, insbesondere für die Handhabung mittels einer optischen Pinzette
WO2005060431A2 (fr) * 2003-10-28 2005-07-07 Arryx, Inc. Systeme et procede de manipulation et de traitement de nano-materiaux faisant appel au piegeage optique holographique
US7449679B2 (en) * 2003-10-28 2008-11-11 Arryx, Inc. System and method for manipulating and processing materials using holographic optical trapping
GB0416498D0 (en) 2004-07-23 2004-08-25 Council Cent Lab Res Councils Optically controllable device
US8169600B2 (en) 2006-09-15 2012-05-01 Arryx, Inc. Surface mapping by optical manipulation of particles in relation to a functionalized surface
WO2008140758A1 (fr) * 2007-05-10 2008-11-20 Pacific Biosciences Of California, Inc. Procédés et systèmes d'analyse de matière fluorescente à autofluorescence limitée
JP2010538645A (ja) * 2007-09-11 2010-12-16 アリックス インク 対象物を選別するための結合方法および装置
WO2009035621A1 (fr) * 2007-09-13 2009-03-19 Arryx, Inc. Procédés et appareils pour trier des objets dans une analyse médico-légale d'arn et dans des diagnostics médicaux
PL2280875T3 (pl) * 2008-04-23 2012-10-31 Signode Int Ip Holdings Llc Urządzenie do opasywania taśmą ściągającą z układem przekładni
US9644229B2 (en) * 2012-06-18 2017-05-09 Sobru Solutions, Inc. Microorganism evaluation system
CN109239937A (zh) * 2018-09-15 2019-01-18 天津大学 一种光镊自动化操控装置
CN113053556A (zh) * 2021-03-10 2021-06-29 暨南大学 具有可重构性的生物微马达阵列及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776674A (en) * 1995-06-05 1998-07-07 Seq, Ltd Chemical biochemical and biological processing in thin films
US6055106A (en) * 1998-02-03 2000-04-25 Arch Development Corporation Apparatus for applying optical gradient forces

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3102523B2 (ja) * 1992-10-12 2000-10-23 日本電信電話株式会社 微粒子の配列制御方法
CN1079158C (zh) * 1996-11-26 2002-02-13 中国科学院上海光学精密机械研究所 光悬浮测量系统

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776674A (en) * 1995-06-05 1998-07-07 Seq, Ltd Chemical biochemical and biological processing in thin films
US6055106A (en) * 1998-02-03 2000-04-25 Arch Development Corporation Apparatus for applying optical gradient forces

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1412519A4 *

Also Published As

Publication number Publication date
HK1078933A1 (en) 2006-03-24
JP2004532991A (ja) 2004-10-28
EP1412519A4 (fr) 2007-07-04
JP4199107B2 (ja) 2008-12-17
CN1715918A (zh) 2006-01-04
CN1715918B (zh) 2010-05-12
CA2451222A1 (fr) 2003-01-03
WO2003001178A2 (fr) 2003-01-03
NZ530239A (en) 2006-08-31
EP1412519A2 (fr) 2004-04-28
CN1545561A (zh) 2004-11-10

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