WO2003000873A3 - Régulation de la sérine/thréonine protéine kinase humaine nek1 - Google Patents
Régulation de la sérine/thréonine protéine kinase humaine nek1 Download PDFInfo
- Publication number
- WO2003000873A3 WO2003000873A3 PCT/EP2002/006879 EP0206879W WO03000873A3 WO 2003000873 A3 WO2003000873 A3 WO 2003000873A3 EP 0206879 W EP0206879 W EP 0206879W WO 03000873 A3 WO03000873 A3 WO 03000873A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- protein kinase
- threonine protein
- human serine
- regulation
- nek1
- Prior art date
Links
- 101001123846 Homo sapiens Serine/threonine-protein kinase Nek1 Proteins 0.000 title 1
- 101001010783 Homo sapiens Endoribonuclease Proteins 0.000 abstract 2
- 101001010787 Homo sapiens Endoribonuclease Proteins 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 206010009944 Colon cancer Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 208000029742 colonic neoplasm Diseases 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002312997A AU2002312997A1 (en) | 2001-06-25 | 2002-06-21 | Regulation of human serine/threonine protein kinase nek1 |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30007101P | 2001-06-25 | 2001-06-25 | |
US60/300,071 | 2001-06-25 | ||
US33144701P | 2001-11-16 | 2001-11-16 | |
US60/331,447 | 2001-11-16 | ||
US33669301P | 2001-12-07 | 2001-12-07 | |
US60/336,693 | 2001-12-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003000873A2 WO2003000873A2 (fr) | 2003-01-03 |
WO2003000873A3 true WO2003000873A3 (fr) | 2003-03-20 |
Family
ID=27404691
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2002/006879 WO2003000873A2 (fr) | 2001-06-25 | 2002-06-21 | Régulation de la sérine/thréonine protéine kinase humaine nek1 |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002312997A1 (fr) |
WO (1) | WO2003000873A2 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2006337085B2 (en) * | 2005-12-27 | 2013-12-19 | Curis, Inc. | Methods of using hedgehog kinase antagonists to inhibit hedgehog signaling and to treat hedgehog mediated disorders |
-
2002
- 2002-06-21 WO PCT/EP2002/006879 patent/WO2003000873A2/fr not_active Application Discontinuation
- 2002-06-21 AU AU2002312997A patent/AU2002312997A1/en not_active Abandoned
Non-Patent Citations (5)
Title |
---|
CHO-CHUNG YOON S: "Antisense oligonucleotide inhibition of serine/threonine kinases: An innovative approach to cancer treatment.", PHARMACOLOGY & THERAPEUTICS, vol. 82, no. 2-3, May 1999 (1999-05-01), pages 437 - 449, XP002224531, ISSN: 0163-7258 * |
DATABASE EMBL [online] 1 October 1996 (1996-10-01), LETWIN ET AL.: "Serine/threonine-protein kinase NEK1 (EC 2.7.1.37)", XP002224533, retrieved from EBI Database accession no. P51954 * |
DATABASE EMBL [online] 27 May 1999 (1999-05-27), KOEHRER ET AL.: "Homo sapiens mRNA; DKFZp564L2416", XP002224532, retrieved from EBI Database accession no. AL050385 * |
LEE J C ET AL: "INHIBITORS OF SERINE/THEONINE KENASES", CURRENT OPINION IN BIOTECHNOLOGY, LONDON, GB, vol. 6, no. 6, 1995, pages 657 - 661, XP000567263, ISSN: 0958-1669 * |
LETWIN K ET AL: "A MAMMALIAN DUAL SPECIFICITY PROTEIN KINASE NEK1 IS RELATED TO THE NIMA CELL CYCLE REGULATOR AND HIGHLY EXPRESSED IN MEIOTIC GERM CELLS", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 11, no. 10, 1992, pages 3521 - 3531, XP002160269, ISSN: 0261-4189 * |
Also Published As
Publication number | Publication date |
---|---|
WO2003000873A2 (fr) | 2003-01-03 |
AU2002312997A1 (en) | 2003-01-08 |
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