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WO2002055710A3 - Regulation de l'acide phosphatase pourpre humain - Google Patents

Regulation de l'acide phosphatase pourpre humain Download PDF

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Publication number
WO2002055710A3
WO2002055710A3 PCT/EP2002/000058 EP0200058W WO02055710A3 WO 2002055710 A3 WO2002055710 A3 WO 2002055710A3 EP 0200058 W EP0200058 W EP 0200058W WO 02055710 A3 WO02055710 A3 WO 02055710A3
Authority
WO
WIPO (PCT)
Prior art keywords
human
acid phosphatase
purple acid
regulation
reagents
Prior art date
Application number
PCT/EP2002/000058
Other languages
English (en)
Other versions
WO2002055710A2 (fr
Inventor
Yonghong Xiao
Original Assignee
Bayer Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft filed Critical Bayer Aktiengesellschaft
Publication of WO2002055710A2 publication Critical patent/WO2002055710A2/fr
Publication of WO2002055710A3 publication Critical patent/WO2002055710A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03002—Acid phosphatase (3.1.3.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des réactifs qui régulent l'acide phosphatase pourpre humain ainsi que des réactifs qui se lient aux produits génétiques de l'acide phosphatase pourpre humain. Ces réactifs peuvent jouer un rôle dans la prévention, l'atténuation ou la correction des dysfonctionnements ou des maladies telles que l'obésité, le diabète, les troubles cardio-vasculaires, les troubles du système nerveux central (SNC), et le cancer.
PCT/EP2002/000058 2001-01-11 2002-01-07 Regulation de l'acide phosphatase pourpre humain WO2002055710A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26067101P 2001-01-11 2001-01-11
US60/260,671 2001-01-11
US30761601P 2001-07-26 2001-07-26
US60/307,616 2001-07-26

Publications (2)

Publication Number Publication Date
WO2002055710A2 WO2002055710A2 (fr) 2002-07-18
WO2002055710A3 true WO2002055710A3 (fr) 2003-04-24

Family

ID=26948131

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/000058 WO2002055710A2 (fr) 2001-01-11 2002-01-07 Regulation de l'acide phosphatase pourpre humain

Country Status (1)

Country Link
WO (1) WO2002055710A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006029319A2 (fr) * 2004-09-09 2006-03-16 The General Hospital Corporation Modulation de l'activite de la phosphatase dans des cellules cardiaques
BRPI0807477A2 (pt) * 2007-02-14 2014-05-13 Karolinska Innovations Ab Uso de um polipeptídeo isolado, polipeptídeo isolado, composição farmacêutica, e, métdo de tratamento de um mamífero

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000031289A1 (fr) * 1998-11-19 2000-06-02 Pharmacia Ab Utilisation de trap activee pour rechercher des inhibiteurs specifiques de trap et technique aidant a l'identification d'un compose destine au traitement de maladies ou pathologies degeneratives provoquant une resorption osseuse accrue
WO2002024924A2 (fr) * 2000-09-21 2002-03-28 Incyte Genomics, Inc. Proteine phosphatases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000031289A1 (fr) * 1998-11-19 2000-06-02 Pharmacia Ab Utilisation de trap activee pour rechercher des inhibiteurs specifiques de trap et technique aidant a l'identification d'un compose destine au traitement de maladies ou pathologies degeneratives provoquant une resorption osseuse accrue
WO2002024924A2 (fr) * 2000-09-21 2002-03-28 Incyte Genomics, Inc. Proteine phosphatases

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 January 1998 (1998-01-01), MCMURRAY, A.A:: "F21A3.2 protein", XP002221134, retrieved from EBI Database accession no. O17825 *
MARSHALL ET AL: "Recombinant Human and Mouse Purple Acid Phosphatases: Expression and Characterization", ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, NEW YORK, US, US, vol. 345, no. 2, 15 September 1997 (1997-09-15), pages 230 - 236, XP002207501, ISSN: 0003-9861 *

Also Published As

Publication number Publication date
WO2002055710A2 (fr) 2002-07-18

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