WO2003000842A3 - Nouvelles proteines et acides nucleiques codant pour de telles proteines - Google Patents
Nouvelles proteines et acides nucleiques codant pour de telles proteines Download PDFInfo
- Publication number
- WO2003000842A3 WO2003000842A3 PCT/US2002/017443 US0217443W WO03000842A3 WO 2003000842 A3 WO2003000842 A3 WO 2003000842A3 US 0217443 W US0217443 W US 0217443W WO 03000842 A3 WO03000842 A3 WO 03000842A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- small molecule
- molecule target
- nucleic acids
- acids encoding
- polynucleotide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002447941A CA2447941A1 (fr) | 2001-06-04 | 2002-06-04 | Nouvelles proteines et acides nucleiques codant pour de telles proteines |
EP02765778A EP1578905A2 (fr) | 2001-06-04 | 2002-06-04 | Nouvelles proteines et acides nucleiques codant pour de telles proteines |
JP2003507229A JP2005518185A (ja) | 2001-06-04 | 2002-06-04 | 新規タンパク質およびそれをコード化する核酸 |
Applications Claiming Priority (72)
Application Number | Priority Date | Filing Date | Title |
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US29566101P | 2001-06-04 | 2001-06-04 | |
US29560701P | 2001-06-04 | 2001-06-04 | |
US60/295,607 | 2001-06-04 | ||
US60/295,661 | 2001-06-04 | ||
US60/295,573 | 2001-06-05 | ||
US29641801P | 2001-06-06 | 2001-06-06 | |
US29640401P | 2001-06-06 | 2001-06-06 | |
US60/296,418 | 2001-06-06 | ||
US60/296,404 | 2001-06-06 | ||
US29657501P | 2001-06-07 | 2001-06-07 | |
US60/296,575 | 2001-06-07 | ||
US29741401P | 2001-06-11 | 2001-06-11 | |
US60/297,414 | 2001-06-11 | ||
US29757301P | 2001-06-12 | 2001-06-12 | |
US29756701P | 2001-06-12 | 2001-06-12 | |
US60/297,567 | 2001-06-12 | ||
US29828501P | 2001-06-14 | 2001-06-14 | |
US60/298,285 | 2001-06-14 | ||
US29852801P | 2001-06-15 | 2001-06-15 | |
US60/298,528 | 2001-06-15 | ||
US29913301P | 2001-06-18 | 2001-06-18 | |
US60/299,133 | 2001-06-18 | ||
US29923001P | 2001-06-19 | 2001-06-19 | |
US60/299,230 | 2001-06-19 | ||
US29994901P | 2001-06-21 | 2001-06-21 | |
US60/299,949 | 2001-06-21 | ||
US30017701P | 2001-06-22 | 2001-06-22 | |
US60/300,177 | 2001-06-22 | ||
US30088301P | 2001-06-26 | 2001-06-26 | |
US60/300,883 | 2001-06-26 | ||
US30153001P | 2001-06-28 | 2001-06-28 | |
US30155001P | 2001-06-28 | 2001-06-28 | |
US60/301,550 | 2001-06-28 | ||
US60/301,530 | 2001-06-28 | ||
US30295101P | 2001-07-03 | 2001-07-03 | |
US60/302,951 | 2001-07-03 | ||
US30889001P | 2001-07-31 | 2001-07-31 | |
US60/308,890 | 2001-07-31 | ||
US32229701P | 2001-09-14 | 2001-09-14 | |
US60/322,297 | 2001-09-14 | ||
US32466901P | 2001-09-25 | 2001-09-25 | |
US60/324,669 | 2001-09-25 | ||
US33747701P | 2001-12-03 | 2001-12-03 | |
US60/337,477 | 2001-12-03 | ||
US34156201P | 2001-12-14 | 2001-12-14 | |
US60/341,562 | 2001-12-14 | ||
US35865602P | 2002-02-21 | 2002-02-21 | |
US35912202P | 2002-02-21 | 2002-02-21 | |
US60/359,122 | 2002-02-21 | ||
US60/358,656 | 2002-02-21 | ||
US35897802P | 2002-02-22 | 2002-02-22 | |
US35912102P | 2002-02-22 | 2002-02-22 | |
US35903502P | 2002-02-22 | 2002-02-22 | |
US35903402P | 2002-02-22 | 2002-02-22 | |
US60/358,978 | 2002-02-22 | ||
US60/359,035 | 2002-02-22 | ||
US60/359,034 | 2002-02-22 | ||
US60/359,121 | 2002-02-22 | ||
US35996402P | 2002-02-27 | 2002-02-27 | |
US60/359,964 | 2002-02-27 | ||
US36085802P | 2002-03-01 | 2002-03-01 | |
US60/360,858 | 2002-03-01 | ||
US36343002P | 2002-03-12 | 2002-03-12 | |
US36367602P | 2002-03-12 | 2002-03-12 | |
US60/363,676 | 2002-03-12 | ||
US60/363,430 | 2002-03-12 | ||
US37134602P | 2002-04-10 | 2002-04-10 | |
US60/371,346 | 2002-04-10 | ||
US37944402P | 2002-05-10 | 2002-05-10 | |
US60/379,444 | 2002-05-10 | ||
US16061902A | 2002-06-03 | 2002-06-03 | |
US10/160,619 | 2002-06-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003000842A2 WO2003000842A2 (fr) | 2003-01-03 |
WO2003000842A3 true WO2003000842A3 (fr) | 2005-11-03 |
Family
ID=34744079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/017443 WO2003000842A2 (fr) | 2001-06-04 | 2002-06-04 | Nouvelles proteines et acides nucleiques codant pour de telles proteines |
Country Status (2)
Country | Link |
---|---|
JP (1) | JP2005518185A (fr) |
WO (1) | WO2003000842A2 (fr) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9295737B2 (en) | 2002-03-01 | 2016-03-29 | Bracco Suisse Sa | Targeting vector-phospholipid conjugates |
US9408926B2 (en) | 2002-03-01 | 2016-08-09 | Bracco Suisse S.A. | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US9446155B2 (en) | 2002-03-01 | 2016-09-20 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US9562049B2 (en) | 2012-12-21 | 2017-02-07 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
US9567340B2 (en) | 2012-12-21 | 2017-02-14 | Medimmune Limited | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
Families Citing this family (81)
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US7041494B2 (en) | 2000-11-15 | 2006-05-09 | Icagen, Inc. | DNA encoding Slo2 and Slo4, potassium channel |
US6815181B2 (en) | 2001-07-09 | 2004-11-09 | Applera Corporation | Nucleic acid molecules encoding human secreted hemopexin-related proteins |
US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
ES2692166T3 (es) | 2003-03-03 | 2018-11-30 | Dyax Corp. | Péptidos que se unen específicamente al receptor de HGF (cMet) y usos de los mismos |
SG10201701737XA (en) | 2003-11-06 | 2017-04-27 | Seattle Genetics Inc | Monomethylvaline compounds capable of conjugation to ligands |
EP1753463A2 (fr) | 2004-06-01 | 2007-02-21 | Genentech, Inc. | Conjugues de medicaments anticorps et procedes correspondants |
US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
ES2669510T3 (es) | 2004-09-23 | 2018-05-28 | Genentech, Inc. | Anticuerpos y conjugados modificados por ingeniería genética con cisteína |
JP2006217859A (ja) * | 2005-02-10 | 2006-08-24 | Japan Health Science Foundation | アルツハイマー病の治療薬または予防薬のスクリーニング方法、およびアルツハイマー病を診断する方法、アルツハイマー病発症の危険度を予測する方法 |
EP1849877A1 (fr) * | 2006-04-24 | 2007-10-31 | Erasmus University Medical Center Rotterdam | Histoire réplicative de sous-ensembles de lymphocytes T et B |
DE102007017433A1 (de) * | 2007-04-03 | 2008-10-09 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | PIKfyve als pharmakologisches Target zur Behandlung von glucosestoffwechselassoziierten Krankheiten |
WO2011031870A1 (fr) | 2009-09-09 | 2011-03-17 | Centrose, Llc | Conjugués médicamenteux ciblés à visée extracellulaire |
EP2528625B1 (fr) | 2010-04-15 | 2013-07-10 | Spirogen Sàrl | Pyrrolobenzodiazépines et conjugués de celles-ci |
SG185428A1 (en) | 2010-06-08 | 2012-12-28 | Genentech Inc | Cysteine engineered antibodies and conjugates |
US20120121615A1 (en) | 2010-11-17 | 2012-05-17 | Flygare John A | Alaninyl maytansinol antibody conjugates |
WO2012112955A2 (fr) | 2011-02-17 | 2012-08-23 | The Trustees Of Columbia University In The City Of New York | Procédés d'identification de sujets présentant un risque génétique de développer une néphropathie à iga |
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JP6104257B2 (ja) | 2011-10-14 | 2017-03-29 | メドイミューン・リミテッドMedImmune Limited | ピロロベンゾジアゼピンおよびそのコンジュゲート |
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WO2014057119A1 (fr) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Conjugués anticorps - pyrrolobenzodiazépine |
MX372691B (es) | 2012-10-12 | 2020-05-28 | Medimmune Ltd | Pirrolobenzodiazepinas y conjugados de las mismas. |
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PT2906298T (pt) | 2012-10-12 | 2018-12-28 | Medimmune Ltd | Conjugados de pirrolobenzodiazepina-anticorpos |
CN105209077B (zh) | 2013-03-13 | 2019-06-11 | 麦迪穆有限责任公司 | 吡咯并苯并二氮杂卓以及其结合物 |
JP6340019B2 (ja) | 2013-03-13 | 2018-06-06 | メドイミューン・リミテッドMedImmune Limited | ピロロベンゾジアゼピン及びそのコンジュゲート |
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WO2014169294A1 (fr) * | 2013-04-12 | 2014-10-16 | The Trustees Of Columbia University In The City Of New York | Mutations dans dstyk provoquant des malformations dominantes dans les voies urinaires |
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GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
GB201814281D0 (en) | 2018-09-03 | 2018-10-17 | Femtogenix Ltd | Cytotoxic agents |
JP2022505450A (ja) | 2018-10-24 | 2022-01-14 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | コンジュゲート化された化学的分解誘導物質および使用方法 |
EP3894427A1 (fr) | 2018-12-10 | 2021-10-20 | Genentech, Inc. | Peptides de photoréticulation pour conjugaison spécifique de site à des protéines contenant fc |
GB201901197D0 (en) | 2019-01-29 | 2019-03-20 | Femtogenix Ltd | G-A Crosslinking cytotoxic agents |
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GB2597532A (en) | 2020-07-28 | 2022-02-02 | Femtogenix Ltd | Cytotoxic compounds |
AU2021362997A1 (en) | 2021-11-03 | 2024-05-16 | Hangzhou Dac Biotech Co., Ltd. | Specific conjugation of an antibody |
TW202432187A (zh) | 2022-12-23 | 2024-08-16 | 美商建南德克公司 | 小腦蛋白降解劑結合物及其用途 |
WO2024220546A2 (fr) | 2023-04-17 | 2024-10-24 | Peak Bio, Inc. | Anticorps et conjugués anticorps-médicament et procédés d'utilisation, processus synthétiques et intermédiaires |
-
2002
- 2002-06-04 WO PCT/US2002/017443 patent/WO2003000842A2/fr not_active Application Discontinuation
- 2002-06-04 JP JP2003507229A patent/JP2005518185A/ja active Pending
Non-Patent Citations (2)
Title |
---|
BIOCHEM. BIOPHYS. ACTA 1519, vol. 1-2, 2001, pages 117 - 121 * |
DATABASE GENBANK [online] VIGETTI D. ET AL: "Molecular cloning of mouse allantoicase cDNA", XP002991050, Database accession no. (AF278712) * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9295737B2 (en) | 2002-03-01 | 2016-03-29 | Bracco Suisse Sa | Targeting vector-phospholipid conjugates |
US9381258B2 (en) | 2002-03-01 | 2016-07-05 | Bracco Suisse S.A. | Targeting vector-phospholipid conjugates |
US9408926B2 (en) | 2002-03-01 | 2016-08-09 | Bracco Suisse S.A. | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US9446155B2 (en) | 2002-03-01 | 2016-09-20 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
US9562049B2 (en) | 2012-12-21 | 2017-02-07 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
US9567340B2 (en) | 2012-12-21 | 2017-02-14 | Medimmune Limited | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
Also Published As
Publication number | Publication date |
---|---|
WO2003000842A2 (fr) | 2003-01-03 |
JP2005518185A (ja) | 2005-06-23 |
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