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WO2003083046A3 - Nouvelles proteines et acides nucleiques codant pour de telles proteines - Google Patents

Nouvelles proteines et acides nucleiques codant pour de telles proteines Download PDF

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Publication number
WO2003083046A3
WO2003083046A3 PCT/US2003/010142 US0310142W WO03083046A3 WO 2003083046 A3 WO2003083046 A3 WO 2003083046A3 US 0310142 W US0310142 W US 0310142W WO 03083046 A3 WO03083046 A3 WO 03083046A3
Authority
WO
WIPO (PCT)
Prior art keywords
small molecule
nucleic acids
molecule target
therapeutic
methods
Prior art date
Application number
PCT/US2003/010142
Other languages
English (en)
Other versions
WO2003083046A2 (fr
Inventor
David W Anderson
Patricia Bento
Ferenc L Boldog
Catherine E Burgess
Stacie J Casman
Katarzyna Furtak
Linda Gorman
Bonnie E Gould-Rothberg
Erik Gunther
Melvyn P Heyes
Li Li
Kimberly A Spytek
David J Stone
Mei Zhong
Uriel M Malyankar
Shlomit R Edinger
Meera Patturajan
Mark E Rothenberg
Glennda Smithson
Original Assignee
Curagen Corp
David W Anderson
Patricia Bento
Ferenc L Boldog
Catherine E Burgess
Stacie J Casman
Katarzyna Furtak
Linda Gorman
Bonnie E Gould-Rothberg
Erik Gunther
Melvyn P Heyes
Li Li
Kimberly A Spytek
David J Stone
Mei Zhong
Uriel M Malyankar
Shlomit R Edinger
Meera Patturajan
Mark E Rothenberg
Glennda Smithson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/093,463 external-priority patent/US20030208039A1/en
Priority claimed from US10/115,479 external-priority patent/US20040006205A1/en
Priority claimed from US10/287,226 external-priority patent/US20040086875A1/en
Application filed by Curagen Corp, David W Anderson, Patricia Bento, Ferenc L Boldog, Catherine E Burgess, Stacie J Casman, Katarzyna Furtak, Linda Gorman, Bonnie E Gould-Rothberg, Erik Gunther, Melvyn P Heyes, Li Li, Kimberly A Spytek, David J Stone, Mei Zhong, Uriel M Malyankar, Shlomit R Edinger, Meera Patturajan, Mark E Rothenberg, Glennda Smithson filed Critical Curagen Corp
Priority to AU2003228426A priority Critical patent/AU2003228426A1/en
Priority to CA002481376A priority patent/CA2481376A1/fr
Priority to EP03726178A priority patent/EP1523322A4/fr
Publication of WO2003083046A2 publication Critical patent/WO2003083046A2/fr
Publication of WO2003083046A3 publication Critical patent/WO2003083046A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention a trait à des nouveaux polynucléotides isolés et des polypeptides cibles à petites molécules codés par les polynucléotides. L'invention a trait également à des anticorps qui se lient de manière immunospécifique à un polypeptide cible nouveau à petites molécules ou tout dérivé, variant, mutant ou fragment dudit polypeptide, polynucléotide ou anticorps, ainsi que des procédés dans lesquels le polypeptide cible à petites molécules, polynucléotide et anticorps sont utilisés dans la détection et le traitement d'une large gamme de conditions pathologiques. De manière plus spécifique, la présente invention a trait à des procédés d'utilisation de protéines exprimées de manière recombinante et/ou exprimées de manière endogène dans diverses procédures de criblage en vue de l'identification d'anticorps thérapeutiques et de petites molécules thérapeutiques associées à des maladies. L'invention a trait en outre à des procédés thérapeutiques, diagnostiques et de recherche pour le diagnostic, le traitement, et la prévention de troubles impliquant un quelconque desdits nouveaux acides nucléiques et protéines humains.
PCT/US2003/010142 2002-03-08 2003-04-01 Nouvelles proteines et acides nucleiques codant pour de telles proteines WO2003083046A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2003228426A AU2003228426A1 (en) 2002-04-02 2003-04-01 Novel proteins and nucleic acids encoding same
CA002481376A CA2481376A1 (fr) 2002-04-02 2003-04-01 Nouvelles proteines et acides nucleiques codant pour de telles proteines
EP03726178A EP1523322A4 (fr) 2002-04-02 2003-04-01 Nouvelles proteines et acides nucleiques codant pour de telles proteines

Applications Claiming Priority (20)

Application Number Priority Date Filing Date Title
US10/093,463 US20030208039A1 (en) 2001-03-08 2002-03-08 Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
US10/115,479 2002-04-02
US10/115,479 US20040006205A1 (en) 2001-04-03 2002-04-02 Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US37034902P 2002-04-05 2002-04-05
US60/370,349 2002-04-05
US37096902P 2002-04-08 2002-04-08
US60/370,969 2002-04-08
US37201902P 2002-04-12 2002-04-12
US60/372,019 2002-04-12
US37437902P 2002-04-22 2002-04-22
US60/374,379 2002-04-22
US38454302P 2002-05-30 2002-05-30
US60/384,543 2002-05-30
US16061902A 2002-06-03 2002-06-03
US10/160,619 2002-06-03
US40374802P 2002-08-15 2002-08-15
US60/403,748 2002-08-15
US10/287,226 US20040086875A1 (en) 2001-11-05 2002-11-04 Novel proteins and nucleic acids encoding same
US10/287,226 2002-11-04
US10/403,161 2003-03-31

Publications (2)

Publication Number Publication Date
WO2003083046A2 WO2003083046A2 (fr) 2003-10-09
WO2003083046A3 true WO2003083046A3 (fr) 2004-07-22

Family

ID=28679254

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/010142 WO2003083046A2 (fr) 2002-03-08 2003-04-01 Nouvelles proteines et acides nucleiques codant pour de telles proteines

Country Status (1)

Country Link
WO (1) WO2003083046A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4628098B2 (ja) 2002-07-03 2011-02-09 イルミゲン バイオサイエンシズ，インコーポレイティド 肝細胞癌を診断する方法と組成物
JP4970057B2 (ja) * 2004-02-24 2012-07-04 アラーガン、インコーポレイテッド ボツリヌス毒素スクリーニングアッセイ
WO2005104785A2 (fr) * 2004-04-27 2005-11-10 Illumigen Biosciences, Inc. Methodes et compositions pour ciblage specifique de cellules du carcinome hepatocellulaire chez l'homme
WO2005118832A2 (fr) * 2004-06-01 2005-12-15 Bayer Healthcare Ag Agents diagnostiques et therapeutiques pour des maladies associees a une proteine de type kinase regulee par serum/glucocorticoide (sgkl)
US7485468B2 (en) 2004-10-15 2009-02-03 Galapagos Bv Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
US8673268B2 (en) 2004-10-15 2014-03-18 Galapagos N.V. Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
CA2587979A1 (fr) * 2004-11-19 2006-05-26 Oy Jurilab Ltd Procede et kit de detection d'un risque d'hypertension arterielle essentielle
DE102004059781A1 (de) * 2004-12-10 2006-06-22 Sanofi-Aventis Deutschland Gmbh Verwendung der Serum-/Glucocorticoid regulierten Kinase
GB0517916D0 (en) * 2005-09-02 2005-10-12 Paradigm Therapeutics Ltd Ion channel
US8187601B2 (en) 2008-07-01 2012-05-29 Aveo Pharmaceuticals, Inc. Fibroblast growth factor receptor 3 (FGFR3) binding proteins

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863780A (en) * 1996-09-12 1999-01-26 Incyte Pharmaceuticals, Inc. Human Protein Kinases
US6326181B1 (en) * 1997-02-28 2001-12-04 Florian Lang Cell volume-regulated human kinase h-sgk

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863780A (en) * 1996-09-12 1999-01-26 Incyte Pharmaceuticals, Inc. Human Protein Kinases
US6326181B1 (en) * 1997-02-28 2001-12-04 Florian Lang Cell volume-regulated human kinase h-sgk

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE PIR_76 [online] R. WEBSTER: "Serum and Glucocorticoid-regulated Kinase-Rat", XP002977288, Database accession no. A48094 *
DATABASE PROTEIN [online] 15 March 1999 (1999-03-15), "Human SQK Protein", Database accession no. AAW90139 *
MOL. CELL. BIOL., 21 January 1994 (1994-01-21) *

Also Published As

Publication number Publication date
WO2003083046A2 (fr) 2003-10-09

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