+

WO2003066831A3 - Genes d'angiogenese - Google Patents

Genes d'angiogenese Download PDF

Info

Publication number
WO2003066831A3
WO2003066831A3 PCT/US2003/003848 US0303848W WO03066831A3 WO 2003066831 A3 WO2003066831 A3 WO 2003066831A3 US 0303848 W US0303848 W US 0303848W WO 03066831 A3 WO03066831 A3 WO 03066831A3
Authority
WO
WIPO (PCT)
Prior art keywords
angiogenesis
polynucleotides
medicine
during angiogenesis
prognosticating
Prior art date
Application number
PCT/US2003/003848
Other languages
English (en)
Other versions
WO2003066831A2 (fr
Inventor
Zairen Sun
Xuan Li
Karl F Kovacs
Wufang Fan
Gilbert Jay
Original Assignee
Origene Technologies Inc
Zairen Sun
Xuan Li
Karl F Kovacs
Wufang Fan
Gilbert Jay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/067,482 external-priority patent/US20030148407A1/en
Priority claimed from US10/164,595 external-priority patent/US6657054B1/en
Application filed by Origene Technologies Inc, Zairen Sun, Xuan Li, Karl F Kovacs, Wufang Fan, Gilbert Jay filed Critical Origene Technologies Inc
Priority to AU2003219725A priority Critical patent/AU2003219725A1/en
Publication of WO2003066831A2 publication Critical patent/WO2003066831A2/fr
Publication of WO2003066831A3 publication Critical patent/WO2003066831A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Vascular Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne la totalité des facettes de polynucléotides présentant une régulation diversifiée pendant l'angiogenèse, les polypeptides qu'ils codent, leurs anticorps et partenaires spécifiques de fixation, ainsi que leurs utilisations dans la recherche, le diagnostic, l'élaboration de médicaments, la thérapie, la médecine clinique, la science criminelle ou la médecine scientifique. Ces polynucléotides sont exprimés pendant l'angiogenèse et sont, par conséquent, utiles dans une variété de domaines, y compris, de façon non exhaustive, sous forme de marqueurs moléculaires, de cibles de médicaments, ainsi que pour détecter, diagnostiquer, stadifier, contrôler, pronostiquer, prévenir ou traiter des maladies et des états, tels qu'une angiogenèse anormale, insuffisante ou excessive, et pour déterminer une prédisposition à ces maladies ou à ces états.
PCT/US2003/003848 2002-02-07 2003-02-07 Genes d'angiogenese WO2003066831A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003219725A AU2003219725A1 (en) 2002-02-07 2003-02-07 Angiogenesis genes

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US10/067,482 US20030148407A1 (en) 2002-02-07 2002-02-07 Human dehydrogenase gene and polypeptide
US10/067,482 2002-02-07
US10/164,595 2002-06-10
US10/164,595 US6657054B1 (en) 2002-06-10 2002-06-10 Regulated angiogenesis genes and polypeptides
US40364902P 2002-08-16 2002-08-16
US60/403,649 2002-08-16
US43774603P 2003-01-03 2003-01-03
US60/437,746 2003-01-03

Publications (2)

Publication Number Publication Date
WO2003066831A2 WO2003066831A2 (fr) 2003-08-14
WO2003066831A3 true WO2003066831A3 (fr) 2006-08-17

Family

ID=27739314

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/003848 WO2003066831A2 (fr) 2002-02-07 2003-02-07 Genes d'angiogenese

Country Status (2)

Country Link
AU (1) AU2003219725A1 (fr)
WO (1) WO2003066831A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7055683B2 (en) 2002-12-20 2006-06-06 E. I. Du Pont De Nemours And Company Multiple compartment pouch and beverage container with smooth curve frangible seal
JPWO2004113532A1 (ja) * 2003-06-21 2006-08-03 繁樹 東山 細胞増殖抑制剤スクリーニング用タンパク質及び細胞増殖抑制剤のスクリーニング方法並びに細胞増殖抑制剤
CA2712309A1 (fr) * 2008-01-17 2009-07-23 Toray Industries, Inc. Composition et procede de diagnostic ou de detection du cancer de l'estomac

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CLINE E.I. ET AL.: "Prediction of In Vivo Synergistic Activity of Antiangiogenic Compounds by Gene Expression Profiling", CANCER RES., vol. 62, no. 24, December 2002 (2002-12-01), pages 713 - 7148, XP003002408 *
GERRITSEN M.E. ET AL.: "In Silico Data Filtering to identify New Angiogenesis Targets from a Large In Vitro Gene Profiling Data Set", PHYSIOL GENOMICS, vol. 10, no. 1, July 2002 (2002-07-01), pages 13 - 20, XP003002409 *
GLIENKE J. ET AL.: "Differential Gene Expression by Endothelial Cells in Distinct Angiogenic States", EUR. J. BIOCHEM., vol. 267, no. 9, May 2000 (2000-05-01), pages 2820 - 2830, XP002213005 *
KAHN J. ET AL: "Gene Expression Profiling in an In Vitro Model of Angiogenesis", AM. J. PATHOL., vol. 156, no. 6, June 2000 (2000-06-01), pages 1887 - 1900, XP002178225 *
PROLS F. ET AL.: "Differential Expression of Osteopontin, PC4, and CEC5, a Novel mRNA Species, During In Vitro Angiogenesis", EXP. CELL RES., vol. 239, no. 1, February 1998 (1998-02-01), pages 1 - 10, XP000949306 *

Also Published As

Publication number Publication date
AU2003219725A8 (en) 2003-09-02
AU2003219725A1 (en) 2003-09-02
WO2003066831A2 (fr) 2003-08-14

Similar Documents

Publication Publication Date Title
WO2003085095A3 (fr) Nouveaux genes exprimes
WO2003029421A3 (fr) Genes regules du cancer du sein
WO2003063773A3 (fr) Genes du cancer de la prostate a regulation differenciee
WO2003040331A3 (fr) Genes du cancer de la prostate
WO2002055740A3 (fr) Methodes de detection de mutations au moyen d'extensions d'amorce pouvant detecter une maladie
WO2004047863A3 (fr) Produits geniques exprimes de maniere differentielle dans des tumeurs et leur utilisation
WO2005072340A3 (fr) Nouveaux polynucleotides codant pour des polypeptides et leurs procedes d'utilisation
WO2005044990A3 (fr) Sequences d'acide nucleique differemment exprimees utilisees comme biomarqueurs du cancer
WO2004067570A3 (fr) Diagnostic et traitement du cancer de la prostate
WO2004097052A3 (fr) Procedes de pronostic et de traitement de tumeurs solides
WO2002057741A3 (fr) Anticorps monoclonaux et antigenes de surface pour la detection et le traitement du cancer a petites cellules (sclc)
WO1999047669A3 (fr) Sequences d'acide nucleique humain tirees de tissus de tumeurs du sein
WO2002086448A3 (fr) Detection de l'instabilite des microsatellites et son utilisation dans le diagnostic des tumeurs
WO2002081638A3 (fr) Profils d'expression de cancer de la prostate
WO2005087953A3 (fr) Polymorphismes genetiques associes a des maladies coronariennes, procedes de detection et utilisations
WO2003016485A3 (fr) Serine-proteine-kinase de longueur totale dans le cerveau et dans le pancreas
WO2004003144A3 (fr) Anticorps qui se lient specifiquement a reg iv
WO2003014298A3 (fr) Polynucleotides et polypeptides selectifs pour la prostate et presentant une longueur totale de chaine
WO2003064599A3 (fr) Genes du cancer
WO2003066831A3 (fr) Genes d'angiogenese
CA2534643A1 (fr) Procedes de detection et d'identification de composes
WO2001061055A3 (fr) Procedes de diagnostic, de monitorage, de stadage, d'imagerie et de traitement du cancer du poumon par le biais de genes specifiques du cancer du poumon
WO1999047655A3 (fr) Sequences d'acides nucleiques humains provenant de tissus mammaires sains
WO2000058510A3 (fr) Genes, proteines, et marqueurs bialleliques associes a la schizophrenie
WO2003054167A3 (fr) Identification de sites polymorphes dans le gene humain mglur8 et utilisations associees

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载