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WO2003066831A3 - Angiogenesis genes - Google Patents

Angiogenesis genes Download PDF

Info

Publication number
WO2003066831A3
WO2003066831A3 PCT/US2003/003848 US0303848W WO03066831A3 WO 2003066831 A3 WO2003066831 A3 WO 2003066831A3 US 0303848 W US0303848 W US 0303848W WO 03066831 A3 WO03066831 A3 WO 03066831A3
Authority
WO
WIPO (PCT)
Prior art keywords
angiogenesis
polynucleotides
medicine
during angiogenesis
prognosticating
Prior art date
Application number
PCT/US2003/003848
Other languages
French (fr)
Other versions
WO2003066831A2 (en
Inventor
Zairen Sun
Xuan Li
Karl F Kovacs
Wufang Fan
Gilbert Jay
Original Assignee
Origene Technologies Inc
Zairen Sun
Xuan Li
Karl F Kovacs
Wufang Fan
Gilbert Jay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/067,482 external-priority patent/US20030148407A1/en
Priority claimed from US10/164,595 external-priority patent/US6657054B1/en
Application filed by Origene Technologies Inc, Zairen Sun, Xuan Li, Karl F Kovacs, Wufang Fan, Gilbert Jay filed Critical Origene Technologies Inc
Priority to AU2003219725A priority Critical patent/AU2003219725A1/en
Publication of WO2003066831A2 publication Critical patent/WO2003066831A2/en
Publication of WO2003066831A3 publication Critical patent/WO2003066831A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to all facets of polynucleotides differentially regulated during angiogenesis, the polypeptides they encode, antibodies and specific binding partners thereto, and their applications to research, diagnosis, drug discovery, therapy, clinical medicine, forensic science and medicine, etc. The polynucleotides are expressed during angiogenesis and are therefore useful in variety of ways, including, but not limited to, as molecular markers, as drug targets, and for detecting, diagnosing, staging, monitoring, prognosticating,preventing or treating, determining predisposition to,etc,. diseases and conditions, such as abnormal, insufficient, excessive, etc., angiogenesis.
PCT/US2003/003848 2002-02-07 2003-02-07 Angiogenesis genes WO2003066831A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003219725A AU2003219725A1 (en) 2002-02-07 2003-02-07 Angiogenesis genes

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US10/067,482 US20030148407A1 (en) 2002-02-07 2002-02-07 Human dehydrogenase gene and polypeptide
US10/067,482 2002-02-07
US10/164,595 US6657054B1 (en) 2002-06-10 2002-06-10 Regulated angiogenesis genes and polypeptides
US10/164,595 2002-06-10
US40364902P 2002-08-16 2002-08-16
US60/403,649 2002-08-16
US43774603P 2003-01-03 2003-01-03
US60/437,746 2003-01-03

Publications (2)

Publication Number Publication Date
WO2003066831A2 WO2003066831A2 (en) 2003-08-14
WO2003066831A3 true WO2003066831A3 (en) 2006-08-17

Family

ID=27739314

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/003848 WO2003066831A2 (en) 2002-02-07 2003-02-07 Angiogenesis genes

Country Status (2)

Country Link
AU (1) AU2003219725A1 (en)
WO (1) WO2003066831A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7055683B2 (en) 2002-12-20 2006-06-06 E. I. Du Pont De Nemours And Company Multiple compartment pouch and beverage container with smooth curve frangible seal
JPWO2004113532A1 (en) * 2003-06-21 2006-08-03 繁樹 東山 Protein for screening cell growth inhibitor, screening method for cell growth inhibitor, and cell growth inhibitor
CA2712309A1 (en) * 2008-01-17 2009-07-23 Toray Industries, Inc. Composition and method for diagnosis or detection of renal cancer

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CLINE E.I. ET AL.: "Prediction of In Vivo Synergistic Activity of Antiangiogenic Compounds by Gene Expression Profiling", CANCER RES., vol. 62, no. 24, December 2002 (2002-12-01), pages 713 - 7148, XP003002408 *
GERRITSEN M.E. ET AL.: "In Silico Data Filtering to identify New Angiogenesis Targets from a Large In Vitro Gene Profiling Data Set", PHYSIOL GENOMICS, vol. 10, no. 1, July 2002 (2002-07-01), pages 13 - 20, XP003002409 *
GLIENKE J. ET AL.: "Differential Gene Expression by Endothelial Cells in Distinct Angiogenic States", EUR. J. BIOCHEM., vol. 267, no. 9, May 2000 (2000-05-01), pages 2820 - 2830, XP002213005 *
KAHN J. ET AL: "Gene Expression Profiling in an In Vitro Model of Angiogenesis", AM. J. PATHOL., vol. 156, no. 6, June 2000 (2000-06-01), pages 1887 - 1900, XP002178225 *
PROLS F. ET AL.: "Differential Expression of Osteopontin, PC4, and CEC5, a Novel mRNA Species, During In Vitro Angiogenesis", EXP. CELL RES., vol. 239, no. 1, February 1998 (1998-02-01), pages 1 - 10, XP000949306 *

Also Published As

Publication number Publication date
WO2003066831A2 (en) 2003-08-14
AU2003219725A1 (en) 2003-09-02
AU2003219725A8 (en) 2003-09-02

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