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WO2002038587A3 - Haplotypes of the grm8 gene - Google Patents

Haplotypes of the grm8 gene Download PDF

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Publication number
WO2002038587A3
WO2002038587A3 PCT/US2001/047325 US0147325W WO0238587A3 WO 2002038587 A3 WO2002038587 A3 WO 2002038587A3 US 0147325 W US0147325 W US 0147325W WO 0238587 A3 WO0238587 A3 WO 0238587A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
grm8
gene
disclosed
grm8 gene
Prior art date
Application number
PCT/US2001/047325
Other languages
French (fr)
Other versions
WO2002038587A2 (en
Inventor
Karyn M Bieglecki
Anne Chew
Julie Y Choi
Beena Koshy
Katie E Parks
Original Assignee
Genaissance Pharmaceuticals
Karyn M Bieglecki
Anne Chew
Julie Y Choi
Beena Koshy
Katie E Parks
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Karyn M Bieglecki, Anne Chew, Julie Y Choi, Beena Koshy, Katie E Parks filed Critical Genaissance Pharmaceuticals
Priority to AU2002236585A priority Critical patent/AU2002236585A1/en
Publication of WO2002038587A2 publication Critical patent/WO2002038587A2/en
Publication of WO2002038587A3 publication Critical patent/WO2002038587A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel genetic variants of the Glutamate Receptor, Metabotropic 8 (GRM8) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the GRM8 gene. Compositions and methods for haplotyping and/or genotyping the GRM8 gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
PCT/US2001/047325 2000-11-09 2001-11-09 Haplotypes of the grm8 gene WO2002038587A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002236585A AU2002236585A1 (en) 2000-11-09 2001-11-09 Haplotypes of the grm8 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24757600P 2000-11-09 2000-11-09
US60/247,576 2000-11-09

Publications (2)

Publication Number Publication Date
WO2002038587A2 WO2002038587A2 (en) 2002-05-16
WO2002038587A3 true WO2002038587A3 (en) 2003-01-16

Family

ID=22935426

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/047325 WO2002038587A2 (en) 2000-11-09 2001-11-09 Haplotypes of the grm8 gene

Country Status (2)

Country Link
AU (1) AU2002236585A1 (en)
WO (1) WO2002038587A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003054167A2 (en) * 2001-12-20 2003-07-03 Merck & Co., Inc. Identification of novel polymorphic sites in the human mglur8 gene and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BOLONNA ET AL.: "Polymorphisms in the genes ofr mGluR types 7 and 8: association studies with schizophrenia", SCHIZOPHRENIA RESEARCH, vol. 47, no. 1, 2001, pages 99 - 103, XP002951217 *
GOODWIN ET AL.: "No association found between polymorphisms in genes encoding mGluR7 and mGluR8 and idiopathic generalised epilepsy in a case control study", EPILEPSY RESEARCH, vol. 39, 2000, pages 27 - 31, XP002951216 *
SCHERER ET AL.: "The human metabotropic glutamate receptor 8 (GRM8) gene: a disproportionately large gene located at 7q31.3-q32.1", GENOMICS, vol. 44, 1997, pages 232 - 236, XP002104697 *

Also Published As

Publication number Publication date
AU2002236585A1 (en) 2002-05-21
WO2002038587A2 (en) 2002-05-16

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