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WO2002033080A3 - Regulation du recepteur humain membranaire liant la netrine unc5h-1 - Google Patents

Regulation du recepteur humain membranaire liant la netrine unc5h-1 Download PDF

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Publication number
WO2002033080A3
WO2002033080A3 PCT/EP2001/011891 EP0111891W WO0233080A3 WO 2002033080 A3 WO2002033080 A3 WO 2002033080A3 EP 0111891 W EP0111891 W EP 0111891W WO 0233080 A3 WO0233080 A3 WO 0233080A3
Authority
WO
WIPO (PCT)
Prior art keywords
unc5h
membrane receptor
binding membrane
regulation
human netrin
Prior art date
Application number
PCT/EP2001/011891
Other languages
English (en)
Other versions
WO2002033080A2 (fr
Inventor
Rainer H Koehler
Original Assignee
Bayer Ag
Rainer H Koehler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Rainer H Koehler filed Critical Bayer Ag
Priority to AU2001293870A priority Critical patent/AU2001293870A1/en
Publication of WO2002033080A2 publication Critical patent/WO2002033080A2/fr
Publication of WO2002033080A3 publication Critical patent/WO2002033080A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des réactifs qui régulent le récepteur humain membranaire liant la nétrine UNC5H-1 et des réactifs qui se lient à des produits géniques du récepteur humain membranaire liant la nétrine UNC5H-1. Ces réactifs peuvent jouer un rôle dans la prévention, l'amélioration ou la correction d'états de dysfonctionnement ou maladifs, notamment, mais pas exclusivement, du cancer et de troubles du système nerveux central.
PCT/EP2001/011891 2000-10-16 2001-10-15 Regulation du recepteur humain membranaire liant la netrine unc5h-1 WO2002033080A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001293870A AU2001293870A1 (en) 2000-10-16 2001-10-15 Regulation of human netrin binding membrane receptor unc5h-1

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24006100P 2000-10-16 2000-10-16
US60/240,061 2000-10-16

Publications (2)

Publication Number Publication Date
WO2002033080A2 WO2002033080A2 (fr) 2002-04-25
WO2002033080A3 true WO2002033080A3 (fr) 2002-10-31

Family

ID=22904952

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/011891 WO2002033080A2 (fr) 2000-10-16 2001-10-15 Regulation du recepteur humain membranaire liant la netrine unc5h-1

Country Status (2)

Country Link
AU (1) AU2001293870A1 (fr)
WO (1) WO2002033080A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005275062A1 (en) * 2004-07-14 2006-02-23 University Of Utah Research Foundation Netrin-related compositions and uses
EP2708231A1 (fr) 2012-09-12 2014-03-19 Netris Pharma Traitement combiné de médicament interférant netrin-1 et médicament chimiothérapeutique
EP2893939A1 (fr) 2014-01-10 2015-07-15 Netris Pharma Anticorps anti-nétrine-1

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037085A1 (fr) * 1997-02-19 1998-08-27 The Regents Of The University Of California Recepteurs de netrine
WO2000073328A2 (fr) * 1999-06-01 2000-12-07 Devgen Nv Constructions d'unc-5 et methodes de selection
WO2001075440A2 (fr) * 2000-03-31 2001-10-11 Mitsubishi Pharma Corporation Genes associes a la schizophrenie
WO2001098354A2 (fr) * 2000-06-21 2001-12-27 Incyte Genomics, Inc. Recepteurs
WO2002010216A2 (fr) * 2000-07-28 2002-02-07 Curagen Corporation Nouvelles proteines et acides nucleiques codant pour elles

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037085A1 (fr) * 1997-02-19 1998-08-27 The Regents Of The University Of California Recepteurs de netrine
WO2000073328A2 (fr) * 1999-06-01 2000-12-07 Devgen Nv Constructions d'unc-5 et methodes de selection
WO2001075440A2 (fr) * 2000-03-31 2001-10-11 Mitsubishi Pharma Corporation Genes associes a la schizophrenie
WO2001098354A2 (fr) * 2000-06-21 2001-12-27 Incyte Genomics, Inc. Recepteurs
WO2002010216A2 (fr) * 2000-07-28 2002-02-07 Curagen Corporation Nouvelles proteines et acides nucleiques codant pour elles

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 16 June 2001 (2001-06-16), STRAUSBERG R.: "Homo sapiens, Similar to transmembrane receptor Unc5H1, clone IMAGE:4126760, mRNA, partial cds", XP002208343, retrieved from EBI Database accession no. BC009333 *
DATABASE GSN [online] 21 December 1998 (1998-12-21), HINCK L ET AL: "Human UNC-5 homologue unc5h-1 cDNA", XP002208342, retrieved from EBI Database accession no. AAV52941 *
LEONARDO E DAVID ET AL: "Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors", NATURE, MACMILLAN MAGAZINES, US, vol. 386, no. 6627, 1997, pages 833 - 838, XP002149239, ISSN: 0028-0836 *
LIVESEY F J: "NETRINS AND NETRIN RECEPTORS", CMLS CELLULAR AND MOLECULAR LIFE SCIENCES, BIRKHAUSER VERLAG, BASEL, CH, vol. 56, no. 1/2, 1999, pages 62 - 68, XP000946825, ISSN: 1420-682X *

Also Published As

Publication number Publication date
WO2002033080A2 (fr) 2002-04-25
AU2001293870A1 (en) 2002-04-29

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