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WO2002014368A3 - Nouvelles proteines et acides nucleiques codant pour ces proteines - Google Patents

Nouvelles proteines et acides nucleiques codant pour ces proteines Download PDF

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Publication number
WO2002014368A3
WO2002014368A3 PCT/US2001/025624 US0125624W WO0214368A3 WO 2002014368 A3 WO2002014368 A3 WO 2002014368A3 US 0125624 W US0125624 W US 0125624W WO 0214368 A3 WO0214368 A3 WO 0214368A3
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WO
WIPO (PCT)
Prior art keywords
proteins
nucleic acids
same
acids encoding
disclosed
Prior art date
Application number
PCT/US2001/025624
Other languages
English (en)
Other versions
WO2002014368A2 (fr
WO2002014368A8 (fr
Inventor
Bryan D Zerhusen
Muralidhara Padigaru
Kimberly A Spytek
Steven K Spaderna
Esha A Gangolii
Luca Rastelli
Catherine E Burgess
Kumud Majumder
Richard Shimkets
Vishnu Mishra
Corine A M Vernet
Edward S Szekeres
William M Grosse
John P Ii Alsobrook
Xiaohong Liu
Valerie L Gerlach
Karen Ellerman
Glennda Smithson
John Peyman
David Stone
John Macdougall
Original Assignee
Curagen Corp
Bryan D Zerhusen
Muralidhara Padigaru
Kimberly A Spytek
Steven K Spaderna
Esha A Gangolii
Luca Rastelli
Catherine E Burgess
Kumud Majumder
Richard Shimkets
Vishnu Mishra
Corine A M Vernet
Edward S Szekeres
William M Grosse
John P Ii Alsobrook
Xiaohong Liu
Valerie L Gerlach
Karen Ellerman
Glennda Smithson
John Peyman
David Stone
John Macdougall
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curagen Corp, Bryan D Zerhusen, Muralidhara Padigaru, Kimberly A Spytek, Steven K Spaderna, Esha A Gangolii, Luca Rastelli, Catherine E Burgess, Kumud Majumder, Richard Shimkets, Vishnu Mishra, Corine A M Vernet, Edward S Szekeres, William M Grosse, John P Ii Alsobrook, Xiaohong Liu, Valerie L Gerlach, Karen Ellerman, Glennda Smithson, John Peyman, David Stone, John Macdougall filed Critical Curagen Corp
Priority to AU2001284966A priority Critical patent/AU2001284966A1/en
Publication of WO2002014368A2 publication Critical patent/WO2002014368A2/fr
Publication of WO2002014368A8 publication Critical patent/WO2002014368A8/fr
Publication of WO2002014368A3 publication Critical patent/WO2002014368A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des séquences d'acides nucléiques codant pour des nouveaux polypeptides. L'invention concerne également des polypeptides codés par ces séquences d'acides nucléiques, des anticorps se liant de manière immunospécifique à ces polypeptides, ainsi que des dérivés, des variantes, des mutants ou des fragments desdits polypeptides, polynucléotides ou anticorps. L'invention se rapporte en outre à une méthode de traitement, de diagnostic et de recherche servant à diagnostiquer, traiter et prévenir des troubles associés à des acides nucléiques humains et à des protéines humaines de ce type.
PCT/US2001/025624 2000-08-16 2001-08-16 Nouvelles proteines et acides nucleiques codant pour ces proteines WO2002014368A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001284966A AU2001284966A1 (en) 2000-08-16 2001-08-16 Proteins and nucleic acids encoding the same

Applications Claiming Priority (22)

Application Number Priority Date Filing Date Title
US22569200P 2000-08-16 2000-08-16
US22583700P 2000-08-16 2000-08-16
US22569300P 2000-08-16 2000-08-16
US60/225,693 2000-08-16
US60/225,692 2000-08-16
US60/225,837 2000-08-16
US22623600P 2000-08-18 2000-08-18
US22635300P 2000-08-18 2000-08-18
US60/226,353 2000-08-18
US60/226,236 2000-08-18
US22708500P 2000-08-22 2000-08-22
US60/227,085 2000-08-22
US22739500P 2000-08-23 2000-08-23
US60/227,395 2000-08-23
US22760000P 2000-08-24 2000-08-24
US22749200P 2000-08-24 2000-08-24
US60/227,600 2000-08-24
US60/227,492 2000-08-24
US27595201P 2001-03-14 2001-03-14
US60/275,952 2001-03-14
US09/930,512 US20040010118A1 (en) 2000-08-16 2001-08-15 Novel proteins and nucleic acids encoding same
US09/930,512 2001-08-15

Publications (3)

Publication Number Publication Date
WO2002014368A2 WO2002014368A2 (fr) 2002-02-21
WO2002014368A8 WO2002014368A8 (fr) 2003-02-20
WO2002014368A3 true WO2002014368A3 (fr) 2003-09-25

Family

ID=27582737

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/025624 WO2002014368A2 (fr) 2000-08-16 2001-08-16 Nouvelles proteines et acides nucleiques codant pour ces proteines

Country Status (2)

Country Link
US (1) US20040010118A1 (fr)
WO (1) WO2002014368A2 (fr)

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CHEN J-M ET AL: "CLONING, ISOLATION, AND CHARACTERIZATION OF MAMMALIAN LEGUMAIN, AN ASPARAGINYL ENDOPEPTIDES", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 272, no. 12, 21 March 1997 (1997-03-21), pages 8090 - 8098, XP002065429, ISSN: 0021-9258 *
CHEN J-M ET AL: "Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 441, no. 3, 28 December 1998 (1998-12-28), pages 361 - 365, XP004258964, ISSN: 0014-5793 *
CHOI S.J. ET AL.: "Identification of Human Asparaginyl Endopeptidease (Legumain) as an Inhibitor of Osteoclast Formation and Bone Resorption", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 39, 24 September 1999 (1999-09-24), pages 27747 - 27753, XP002207833 *
DATABASE EMBL [online] 17 June 2000 (2000-06-17), WALL M.: "Human DNA sequence from clone RP11-261A1 on chromosome 13", XP002207834, Database accession no. AL359438 *
DATABASE EMBL [online] 18 April 2000 (2000-04-18), WATERSTONE R.H.: "Homo sapiens chromosome 13 clone RP11-60A7; WORKING DRAFT SEQUENCE, 22 unordered pieces", XP002207835, Database accession no. AC055115 *
DATABASE EMBL [online] 9 March 2001 (2001-03-09), STRAUSBERG R.: "Homo sapiens, protease, cysteine, 1 (legumain), clone MGC:1395 IMAGE:3504506, mRNA, complete cds.", XP002207836, Database accession no. BC003061 *
DATABASE TREMBL [online] 1 June 2001 (2001-06-01), STRAUSBERG R.: "Protease, cysteine, 1 (Legumain); Homo sapiens; placenta", XP002207837, Database accession no. Q9BTY1 *
TANAKA T ET AL: "MOLECULAR CLONING OF A HUMAN CDNA ENCODING PUTATIVE CYSTEINE PROTEASE (PRSC1) AND ITS CHROMOSOME ASSIGNMENT TO 14Q32.1", CYTOGENETICS AND CELL GENETICS, vol. 74, 1996, pages 120 - 123, XP002065428, ISSN: 0301-0171 *

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