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WO2002097031A3 - Molecules utilisees a des fins diagnostiques et therapeutiques - Google Patents

Molecules utilisees a des fins diagnostiques et therapeutiques Download PDF

Info

Publication number
WO2002097031A3
WO2002097031A3 PCT/US2002/010056 US0210056W WO02097031A3 WO 2002097031 A3 WO2002097031 A3 WO 2002097031A3 US 0210056 W US0210056 W US 0210056W WO 02097031 A3 WO02097031 A3 WO 02097031A3
Authority
WO
WIPO (PCT)
Prior art keywords
dithp
provides
therapeutics
diagnostics
diagnostic assays
Prior art date
Application number
PCT/US2002/010056
Other languages
English (en)
Other versions
WO2002097031A2 (fr
Inventor
Abel Daffo
Anissa Lee Jones
Alanna-Phung B Tran
Christopher R Dahl
Darryl Gietzen
Original Assignee
Incyte Genomics Inc
Abel Daffo
Anissa Lee Jones
Alanna-Phung B Tran
Christopher R Dahl
Darryl Gietzen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Abel Daffo, Anissa Lee Jones, Alanna-Phung B Tran, Christopher R Dahl, Darryl Gietzen filed Critical Incyte Genomics Inc
Priority to CA002442705A priority Critical patent/CA2442705A1/fr
Priority to AU2002344208A priority patent/AU2002344208A1/en
Publication of WO2002097031A2 publication Critical patent/WO2002097031A2/fr
Publication of WO2002097031A3 publication Critical patent/WO2002097031A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des polynucléotides humains purifiés utilisés à des fins diagnostiques et thérapeutiques (dithp). L'invention concerne par ailleurs des polypeptides (DITHP) codés par dithp, l'utilisation de dithp, ou de compléments, d'oligonucléotides, ou de fragments de celle-ci dans des méthodes diagnostiques. De plus, l'invention concerne des vecteurs et des cellules hôtes contenant dithp pour l'expression de DITHP. L'invention concerne en outre l'utilisation de DITHP isolée et purifiée pour induire des anticorps et cribler des banques de composés ainsi que l'utilisation des anticorps anti-DITHP dans des méthodes d'agnostiques. L'invention concerne enfin des micro-réseaux contenant dithp et des méthodes d'utilisation correspondantes.
PCT/US2002/010056 2001-03-28 2002-03-27 Molecules utilisees a des fins diagnostiques et therapeutiques WO2002097031A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002442705A CA2442705A1 (fr) 2001-03-28 2002-03-27 Molecules utilisees a des fins diagnostiques et therapeutiques
AU2002344208A AU2002344208A1 (en) 2001-03-28 2002-03-27 Molecules for diagnostics and therapeutics

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
US27961901P 2001-03-28 2001-03-28
US60/279,619 2001-03-28
US28006701P 2001-03-29 2001-03-29
US28006801P 2001-03-29 2001-03-29
US60/280,067 2001-03-29
US60,280,068 2001-03-29
US29128001P 2001-05-16 2001-05-16
US60/291,280 2001-05-16
US29182901P 2001-05-17 2001-05-17
US29184901P 2001-05-17 2001-05-17
US60/291,849 2001-05-17
US60,291,829 2001-05-17
US29942801P 2001-06-19 2001-06-19
US60,299,428 2001-06-19
US30000101P 2001-06-20 2001-06-20
US29977601P 2001-06-20 2001-06-20
US60/299,776 2001-06-20
US60/300,001 2001-06-20

Publications (2)

Publication Number Publication Date
WO2002097031A2 WO2002097031A2 (fr) 2002-12-05
WO2002097031A3 true WO2002097031A3 (fr) 2005-05-12

Family

ID=27578771

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2002/009944 WO2002079449A2 (fr) 2001-03-28 2002-03-27 Molecules permettant de detecter et de traiter des maladies
PCT/US2002/010056 WO2002097031A2 (fr) 2001-03-28 2002-03-27 Molecules utilisees a des fins diagnostiques et therapeutiques

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2002/009944 WO2002079449A2 (fr) 2001-03-28 2002-03-27 Molecules permettant de detecter et de traiter des maladies

Country Status (4)

Country Link
EP (1) EP1383894A2 (fr)
AU (2) AU2002344208A1 (fr)
CA (2) CA2447183A1 (fr)
WO (2) WO2002079449A2 (fr)

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US7227008B2 (en) 1999-04-12 2007-06-05 Agensys, Inc. 13-transmembrane protein expressed in prostate cancer
US7628989B2 (en) 2001-04-10 2009-12-08 Agensys, Inc. Methods of inducing an immune response
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug
CN111621525B (zh) * 2020-06-18 2021-04-23 中赛干细胞基因工程有限公司 Stx1b基因在促进人脂肪间充质干细胞生长和分化中的用途

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US7244827B2 (en) 2000-04-12 2007-07-17 Agensys, Inc. Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer
WO2002074906A2 (fr) * 2001-03-16 2002-09-26 Eli Lilly And Company Proteines de mammiferes lp et reactifs associes
DE60220621T2 (de) 2001-11-09 2008-03-06 Proteologics, Inc. Posh Nukleinsäure, Polypeptide und darauf bezogene Verfahren
US8753822B2 (en) * 2001-12-04 2014-06-17 Wayne State University Neoepitope detection of disease using protein arrays
AU2003228084A1 (en) * 2002-05-28 2003-12-12 Omrix Biopharmaceuticals Inc. Method for obtaining anti-idiotype antibodies
EP1551437A4 (fr) 2002-06-05 2006-03-29 Univ Case Western Reserve Methodes et compositions pour detecter des cancers
AU2003243151A1 (en) 2002-08-16 2004-03-03 Agensys, Inc. Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
TW200418988A (en) * 2002-09-30 2004-10-01 Oncotherapy Science Inc Method for diagnosing prostate cancer
CA2487854A1 (fr) * 2002-10-11 2004-04-22 Yamanouchi Pharmaceutical Co., Ltd. Procede de criblage d'un agent pour le traitement de l'insuffisance renale
EP2314676A1 (fr) * 2002-11-26 2011-04-27 Genentech, Inc. Compositions et procédés pour le traitement de maladies liées au système immunitaire
JP4608694B2 (ja) * 2002-12-27 2011-01-12 富士レビオ株式会社 糖転移酵素、該糖転移酵素をコードする核酸及び該核酸を用いた癌化検定方法
GB0315827D0 (en) * 2003-07-05 2003-08-13 Imp College Innovations Ltd Methods
US20080274975A1 (en) * 2004-04-12 2008-11-06 The Trustees Of Columbia University In The City Of New Yourk Methods and Compositions for Inhibiting Abad/Abeta Protein Interaction
EP1627922A1 (fr) * 2004-08-18 2006-02-22 Sanofi-Aventis Deutschland GmbH Méthode de sélection d'agonistes et d'antagonistes du transporteur de carnitine et son utilisation
GB0423126D0 (en) * 2004-10-18 2004-11-17 Ares Trading Sa Protein
US7727725B2 (en) 2006-04-27 2010-06-01 Celera Corporation Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
US8652472B2 (en) 2006-12-05 2014-02-18 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer
US20110250218A1 (en) * 2008-10-29 2011-10-13 Fong Lawrence H Disease-Associated Antigens and Methods of Use Thereof
US9175353B2 (en) 2008-11-14 2015-11-03 Gen-Probe Incorporated Compositions, kits and methods for detection of campylobacter nucleic acid
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
MX342017B (es) * 2010-03-26 2016-09-09 Dartmouth College Proteina mediadora de celula t regulatoria vista, agentes de enlace de vista y uso de los mismos.
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
CN103209987B (zh) 2010-09-22 2017-06-06 艾丽奥斯生物制药有限公司 取代的核苷酸类似物
EP2794630A4 (fr) 2011-12-22 2015-04-01 Alios Biopharma Inc Analogues de nucléotide phosphorothioate substitués
EP2827876A4 (fr) 2012-03-22 2015-10-28 Alios Biopharma Inc Combinaisons pharmaceutiques comprenant un analogue thionucléotidique
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
FI3421486T3 (fi) 2012-06-22 2023-12-15 Dartmouth College Uusia vista-ig-rakenteita ja vista-ig:n käyttö autoimmuuni-, allergia- ja tulehdushäiriöiden hoitamiseksi
AU2013312211B2 (en) 2012-09-07 2018-03-29 King's College London VISTA modulators for diagnosis and treatment of cancer
EA201691323A1 (ru) 2013-12-24 2016-11-30 Янссен Фармасьютика Нв Анти-vista антитела и фрагменты
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
WO2015191881A2 (fr) 2014-06-11 2015-12-17 Green Kathy A Utilisation d'antagonistes et d'agonistes vista pour supprimer ou améliorer l'immunité humorale
WO2016090347A1 (fr) 2014-12-05 2016-06-09 Immunext, Inc. Identification de vsig8 en tant que récepteur putatif de vista et son utilisation pour produire des modulateurs de vista/vsig8
DK3313882T3 (da) 2015-06-24 2020-05-11 Janssen Pharmaceutica Nv Anti-VISTA antistoffer og fragmenter
TW202216201A (zh) 2016-02-12 2022-05-01 比利時商楊森製藥公司 抗vista抗體及片段、其用途及鑑定其之方法
EP3442579A4 (fr) 2016-04-15 2019-12-18 Immunext Inc. Anticorps anti-vista humain et utilisation associée
US12163950B2 (en) * 2018-06-26 2024-12-10 Duke University Synthetic odorant receptors
CN110714017B (zh) * 2019-11-06 2023-09-01 河南师范大学 锦鲤ptps基因、编码蛋白及应用
CN114317732B (zh) * 2021-04-08 2023-08-18 博尔诚（北京）科技有限公司 用于肺癌筛查的组合物及其应用

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Title
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DATABASE GENBANK [online] 5 August 1998 (1998-08-05), DAVOLI R. ET AL., XP002985582, Database accession no. SSGAPDH *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7227008B2 (en) 1999-04-12 2007-06-05 Agensys, Inc. 13-transmembrane protein expressed in prostate cancer
US7306796B2 (en) 1999-04-12 2007-12-11 Agensys, Inc. 13-transmembrane protein expressed in prostate cancer
US7628989B2 (en) 2001-04-10 2009-12-08 Agensys, Inc. Methods of inducing an immune response
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug
CN111621525B (zh) * 2020-06-18 2021-04-23 中赛干细胞基因工程有限公司 Stx1b基因在促进人脂肪间充质干细胞生长和分化中的用途

Also Published As

Publication number Publication date
WO2002079449A2 (fr) 2002-10-10
EP1383894A2 (fr) 2004-01-28
AU2002344208A8 (en) 2005-11-17
CA2442705A1 (fr) 2002-12-05
WO2002097031A2 (fr) 2002-12-05
CA2447183A1 (fr) 2002-10-10
AU2002338265A1 (en) 2002-10-15
AU2002344208A1 (en) 2002-12-09
WO2002079449A3 (fr) 2003-03-20

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