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WO2001068705A3 - Molecules du type recepteur de l'interleukine 17 et leurs utilisations - Google Patents

Molecules du type recepteur de l'interleukine 17 et leurs utilisations Download PDF

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Publication number
WO2001068705A3
WO2001068705A3 PCT/US2001/008688 US0108688W WO0168705A3 WO 2001068705 A3 WO2001068705 A3 WO 2001068705A3 US 0108688 W US0108688 W US 0108688W WO 0168705 A3 WO0168705 A3 WO 0168705A3
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WO
WIPO (PCT)
Prior art keywords
receptor
polypeptides
methods
molecules
amelioration
Prior art date
Application number
PCT/US2001/008688
Other languages
English (en)
Other versions
WO2001068705A2 (fr
Inventor
Shuqian Jing
Eugene Medlock
Richard Yeh
Scott M Silbiger
Gary S Elliot
Hung Q Nguyen
Original Assignee
Amgen Inc
Shuqian Jing
Eugene Medlock
Richard Yeh
Scott M Silbiger
Gary S Elliot
Hung Q Nguyen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc, Shuqian Jing, Eugene Medlock, Richard Yeh, Scott M Silbiger, Gary S Elliot, Hung Q Nguyen filed Critical Amgen Inc
Priority to AU5902901A priority Critical patent/AU5902901A/xx
Priority to MXPA02009024A priority patent/MXPA02009024A/es
Priority to JP2001567795A priority patent/JP2003527117A/ja
Priority to AU2001259029A priority patent/AU2001259029B2/en
Priority to CA002401273A priority patent/CA2401273A1/fr
Priority to EP01932510A priority patent/EP1265924A2/fr
Publication of WO2001068705A2 publication Critical patent/WO2001068705A2/fr
Publication of WO2001068705A3 publication Critical patent/WO2001068705A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des nouveaux polypeptides du type récepteur de l'interleukine 17 (IL-17) ainsi que des molécules d'acide nucléique codant pour ces polypeptides. L'invention concerne également des vecteurs, des cellules hôtes, des agonistes et des antagonistes (et notamment des agents de liaison sélective), ainsi que des méthodes de production de polypeptides du type récepteur de l'IL-17. L'invention concerne en outre des méthodes destinées au traitement, au diagnostic, à l'amélioration ou à la prévention de maladies associées aux polypeptides du type récepteur de l'IL-17.
PCT/US2001/008688 2000-03-16 2001-03-16 Molecules du type recepteur de l'interleukine 17 et leurs utilisations WO2001068705A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU5902901A AU5902901A (en) 2000-03-16 2001-03-16 Il-17 receptor like molecules and uses thereof
MXPA02009024A MXPA02009024A (es) 2000-03-16 2001-03-16 Moleculas del tipo del receptor il-17 y uso de las mismas.
JP2001567795A JP2003527117A (ja) 2000-03-16 2001-03-16 Ｉｌ−１７レセプター様分子およびその使用
AU2001259029A AU2001259029B2 (en) 2000-03-16 2001-03-16 Il-17 receptor like molecules and uses thereof
CA002401273A CA2401273A1 (fr) 2000-03-16 2001-03-16 Molecules du type recepteur de l'interleukine 17 et leurs utilisations
EP01932510A EP1265924A2 (fr) 2000-03-16 2001-03-16 Molecules du type recepteur de l'interleukine 17 et leurs utilisations

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US18992300P 2000-03-16 2000-03-16
US60/189,923 2000-03-16
US20420800P 2000-05-12 2000-05-12
US60/204,208 2000-05-12
US72323200A 2000-11-27 2000-11-27
US09/723,232 2000-11-27
US26615901P 2001-02-02 2001-02-02
US60/266,159 2001-02-02

Publications (2)

Publication Number Publication Date
WO2001068705A2 WO2001068705A2 (fr) 2001-09-20
WO2001068705A3 true WO2001068705A3 (fr) 2002-07-18

Family

ID=27497823

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/008688 WO2001068705A2 (fr) 2000-03-16 2001-03-16 Molecules du type recepteur de l'interleukine 17 et leurs utilisations

Country Status (8)

Country Link
EP (1) EP1265924A2 (fr)
JP (1) JP2003527117A (fr)
AR (1) AR030554A1 (fr)
AU (2) AU2001259029B2 (fr)
CA (1) CA2401273A1 (fr)
MX (1) MXPA02009024A (fr)
TW (1) TWI322154B (fr)
WO (1) WO2001068705A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9475873B2 (en) 2009-05-05 2016-10-25 Novimmune Sa Nucleic acids encoding anti-IL-17F antibodies and methods of use thereof

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ATE365800T1 (de) 1998-05-15 2007-07-15 Genentech Inc Therapeutische verwendungen von il-17 homologe polypeptide
US7771719B1 (en) 2000-01-11 2010-08-10 Genentech, Inc. Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E
EP1897943B1 (fr) * 1999-12-23 2011-12-14 Genentech, Inc. Polypeptides allogéniques IL-17 et utilisations thérapeutiques
US20040043397A1 (en) 2000-01-11 2004-03-04 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
US7718397B2 (en) 2000-03-21 2010-05-18 Genentech, Inc. Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof
US20030096969A1 (en) 2000-06-02 2003-05-22 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU2007202616B2 (en) * 2000-06-22 2011-08-18 Amgen Inc. IL-17 Like Molecules and Uses Thereof
CA2425506A1 (fr) 2000-10-18 2002-08-01 Immunex Corporation Methodes de traitement de la polyarthrite rhumatoide a l'aide d'antagonistes de l'il-17
EP1543120A4 (fr) * 2002-08-05 2006-01-04 Lilly Co Eli Nouvelles proteines et leurs utilisations
EP1562587A4 (fr) * 2002-09-11 2006-07-19 Genentech Inc Compositions et methodes pour le traitement de maladies du systeme immunitaire
WO2007117762A1 (fr) * 2006-02-10 2007-10-18 Zymogenetics, Inc. Recepteur soluble tronque de l'il-17ra et procedes d'utilisation contre l'inflammation
US7833527B2 (en) 2006-10-02 2010-11-16 Amgen Inc. Methods of treating psoriasis using IL-17 Receptor A antibodies
AU2007325520A1 (en) * 2006-10-13 2008-06-05 The Regents Of The University Of California Cancer treatment
JP5561689B2 (ja) * 2007-11-28 2014-07-30 独立行政法人理化学研究所 Ｉｌ−１７ｒｂ陽性ｎｋｔ細胞を用いたアレルギー性気道炎症及び／又は気道過敏症の治療薬のスクリーニング方法
NZ623706A (en) 2008-05-05 2015-12-24 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
GB0905972D0 (en) * 2009-04-06 2009-05-20 Medical Res Council Antibodies against IL-17BR
MX349856B (es) 2010-01-15 2017-08-16 Kirin Amgen Inc Formulaciones de anticuerpo y regimenes terapeuticos.
PH12012501884B1 (en) * 2010-03-30 2018-04-13 Janssen Biotech Inc Humanized il-25 antibodies
EP2809660B1 (fr) 2012-02-02 2016-01-20 Ensemble Therapeutics Corporation Composés macrocycliques pour une modulation d'il-17

Citations (6)

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Publication number Priority date Publication date Assignee Title
WO1999014240A1 (fr) * 1997-09-17 1999-03-25 Human Genome Sciences, Inc. Proteine de type recepteur d'interleukine 17
WO1999035263A2 (fr) * 1998-01-09 1999-07-15 Immunex Corporation Adn codant il-17rh et polypeptides il-17rh
WO2000055204A1 (fr) * 1999-03-16 2000-09-21 Human Genome Sciences, Inc. Proteine de type recteur de l'interleukine 17
WO2000060080A2 (fr) * 1999-04-05 2000-10-12 Incyte Pharmaceuticals, Inc. Molecules du systeme immunitaire
WO2001057202A2 (fr) * 2000-02-04 2001-08-09 The Board Of Trustees Of The University Of Arkansas Sequences du gene evi27 et proteines codees par ces sequences
WO2001059120A2 (fr) * 2000-02-08 2001-08-16 Amgen, Inc. Molecules de type il-17 et utilisation de ces dernieres

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WO1999035263A2 (fr) * 1998-01-09 1999-07-15 Immunex Corporation Adn codant il-17rh et polypeptides il-17rh
WO2000055204A1 (fr) * 1999-03-16 2000-09-21 Human Genome Sciences, Inc. Proteine de type recteur de l'interleukine 17
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WO2001057202A2 (fr) * 2000-02-04 2001-08-09 The Board Of Trustees Of The University Of Arkansas Sequences du gene evi27 et proteines codees par ces sequences
WO2001059120A2 (fr) * 2000-02-08 2001-08-16 Amgen, Inc. Molecules de type il-17 et utilisation de ces dernieres

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Title
See also references of EP1265924A2 *
TIAN ERMING ET AL: "Evi27 encodes a novel membrane protein with homology to the IL17 receptor.", ONCOGENE, vol. 19, no. 17, 20 April 2000 (2000-04-20), pages 2098 - 2109, XP008000240, ISSN: 0950-9232 *
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9475873B2 (en) 2009-05-05 2016-10-25 Novimmune Sa Nucleic acids encoding anti-IL-17F antibodies and methods of use thereof

Also Published As

Publication number Publication date
TWI322154B (en) 2010-03-21
WO2001068705A2 (fr) 2001-09-20
JP2003527117A (ja) 2003-09-16
EP1265924A2 (fr) 2002-12-18
AU5902901A (en) 2001-09-24
AU2001259029B2 (en) 2006-01-05
AR030554A1 (es) 2003-08-27
MXPA02009024A (es) 2003-02-12
CA2401273A1 (fr) 2001-09-20

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