WO2002044351A3 - Regulation de la coa ligase humaine d'acides gras - Google Patents
Regulation de la coa ligase humaine d'acides gras Download PDFInfo
- Publication number
- WO2002044351A3 WO2002044351A3 PCT/EP2001/013795 EP0113795W WO0244351A3 WO 2002044351 A3 WO2002044351 A3 WO 2002044351A3 EP 0113795 W EP0113795 W EP 0113795W WO 0244351 A3 WO0244351 A3 WO 0244351A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fatty acid
- coa ligase
- acid coa
- human fatty
- regulation
- Prior art date
Links
- 108090000364 Ligases Proteins 0.000 title abstract 3
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 3
- 229930195729 fatty acid Natural products 0.000 title abstract 3
- 239000000194 fatty acid Substances 0.000 title abstract 3
- 150000004665 fatty acids Chemical class 0.000 title abstract 3
- 102000003960 Ligases Human genes 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 201000011529 cardiovascular cancer Diseases 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002227949A AU2002227949A1 (en) | 2000-12-01 | 2001-11-27 | Regulation of human fatty acid coa ligase |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25012300P | 2000-12-01 | 2000-12-01 | |
US60/250,123 | 2000-12-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002044351A2 WO2002044351A2 (fr) | 2002-06-06 |
WO2002044351A3 true WO2002044351A3 (fr) | 2002-11-21 |
Family
ID=22946378
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2001/013795 WO2002044351A2 (fr) | 2000-12-01 | 2001-11-27 | Regulation de la coa ligase humaine d'acides gras |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002227949A1 (fr) |
WO (1) | WO2002044351A2 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1456400A4 (fr) * | 2001-12-19 | 2005-09-14 | Exelixis Inc | Modulation de la signalisation des recepteurs de l'insuline par ciblage de genes de facl (acyl-coa synthetase)) |
-
2001
- 2001-11-27 AU AU2002227949A patent/AU2002227949A1/en not_active Abandoned
- 2001-11-27 WO PCT/EP2001/013795 patent/WO2002044351A2/fr not_active Application Discontinuation
Non-Patent Citations (11)
Title |
---|
[online] EBI; 1 August 1998 (1998-08-01), "SA gene", XP002213134, retrieved from EMBL Database accession no. O60363 * |
[online] EBI; 15 April 1994 (1994-04-15), "Human SA mRNA for SA gene product, acetyl-CoA synthetase homologue", XP002213135, retrieved from EMBL Database accession no. D16350 * |
[online] EBI; 2 February 1995 (1995-02-02), "H. sapiens SA mRNA", XP002213136, retrieved from EMBL Database accession no. X80062 * |
[online] EBI; 27 November 1998 (1998-11-27), "Mus musculus SA protein mRNA", XP002213137, retrieved from EMBL Database accession no. AF068246 * |
[online] EBI; 4 June 1999 (1999-06-04), "Bos taurus mitochondrial mRNA for xenobiotic/medium chain fatty acid:CoA ligase from XL-III", XP002213138, retrieved from EMBL Database accession no. AJ132751 * |
FUJINO TAKAHIRO ET AL: "Molecular identification and characterization of two medium-chain acyl-CoA synthetases, MACS1 and the Sa gene product.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 38, 21 September 2001 (2001-09-21), pages 35961 - 35966, XP001094129, ISSN: 0021-9258 * |
IWAI NAOHARU ET AL: "Association between SAH, an acyl-CoA synthetase gene, and hypertriglyceridemia, obesity, and hypertension.", CIRCULATION, vol. 105, no. 1, January 1-8, 2002, pages 41 - 47, XP001105333, ISSN: 0009-7322 * |
IWAI NAOHARU ET AL: "Human SA gene locus as a candidate locus for essential hypertension.", HYPERTENSION (DALLAS), vol. 23, no. 3, March 1994 (1994-03-01), pages 375 - 380, XP001097389, ISSN: 0194-911X * |
KNIGHTS K M ET AL: "Xenobiotic-CoA ligases: Kinetic and molecular characterization.", CURRENT DRUG METABOLISM, vol. 1, no. 1, July 2000 (2000-07-01), July, 2000, pages 49 - 66, XP001105301, ISSN: 1389-2002 * |
LOFTUS BRENDAN J ET AL: "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.", GENOMICS, vol. 60, no. 3, 15 September 1999 (1999-09-15), pages 295 - 308, XP002177511, ISSN: 0888-7543 * |
NABIKA TORU ET AL: "Evaluation of the SA Locus in Human Hypertension.", HYPERTENSION (DALLAS), vol. 25, no. 1, 1995, pages 6 - 13, XP001104818, ISSN: 0194-911X * |
Also Published As
Publication number | Publication date |
---|---|
AU2002227949A1 (en) | 2002-06-11 |
WO2002044351A2 (fr) | 2002-06-06 |
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