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WO2001077132A3 - Haplotypes of the il5 gene - Google Patents

Haplotypes of the il5 gene Download PDF

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Publication number
WO2001077132A3
WO2001077132A3 PCT/US2001/012011 US0112011W WO0177132A3 WO 2001077132 A3 WO2001077132 A3 WO 2001077132A3 US 0112011 W US0112011 W US 0112011W WO 0177132 A3 WO0177132 A3 WO 0177132A3
Authority
WO
WIPO (PCT)
Prior art keywords
gene
haplotypes
disclosed
polymorphisms
haplotyping
Prior art date
Application number
PCT/US2001/012011
Other languages
French (fr)
Other versions
WO2001077132A2 (en
Inventor
Steven C Bentivegna
Anne Chew
Julie Y Choi
R Rex Denton
Amir Kazemi
Krishnan Nandabalan
Katie E Parks
Original Assignee
Genaissance Pharmaceuticals
Steven C Bentivegna
Anne Chew
Julie Y Choi
R Rex Denton
Amir Kazemi
Krishnan Nandabalan
Katie E Parks
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Steven C Bentivegna, Anne Chew, Julie Y Choi, R Rex Denton, Amir Kazemi, Krishnan Nandabalan, Katie E Parks filed Critical Genaissance Pharmaceuticals
Priority to AU2001253430A priority Critical patent/AU2001253430A1/en
Publication of WO2001077132A2 publication Critical patent/WO2001077132A2/en
Publication of WO2001077132A3 publication Critical patent/WO2001077132A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel single nucleotide polymorphisms in the human Interleukin 5 (IL5) gene are described. In addition, various genotypes, haplotypes and haplotype pairs for the IL5 gene that exist in the population are described. Compositions and methods for haplotyping and/or genotyping the IL5 gene in an individual are also disclosed. Polynucleotides containing one or more of the IL5 polymorphisms disclosed herein are also described.
PCT/US2001/012011 2000-04-11 2001-04-11 Haplotypes of the il5 gene WO2001077132A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001253430A AU2001253430A1 (en) 2000-04-11 2001-04-11 Haplotypes of the il5 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19625000P 2000-04-11 2000-04-11
US60/196,250 2000-04-11

Publications (2)

Publication Number Publication Date
WO2001077132A2 WO2001077132A2 (en) 2001-10-18
WO2001077132A3 true WO2001077132A3 (en) 2002-02-28

Family

ID=22724616

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/012011 WO2001077132A2 (en) 2000-04-11 2001-04-11 Haplotypes of the il5 gene

Country Status (2)

Country Link
AU (1) AU2001253430A1 (en)
WO (1) WO2001077132A2 (en)

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CAMPBELL ET AL.: "Molecular cloning, nucleotide sequence and expression of the gene encoding human eosinophil differentiation factor (interleukin 5)", PROC. NATL. ACAD. SCI. USA, vol. 84, October 1987 (1987-10-01), pages 6629 - 6633, XP002949155 *
DATABASE GENEMBL [online] January 1998 (1998-01-01), CONNOLLY ET AL.: "Homo sapiens chromosome 5, PI clone 96c7", XP002949156, Database accession no. AC004042.1 *
SAMBROOK ET AL.: "Molecular cloning: A laboratory manual", 1989, COLD SPRING HARBOR LABORATORY PRESS, COLD SPRING HARBOR, XP002949157 *

Also Published As

Publication number Publication date
WO2001077132A2 (en) 2001-10-18
AU2001253430A1 (en) 2001-10-23

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