WO2001075040A3 - Nouveau polypeptide, pterine-molybdene oxydoreductase humaine 12, et polynucleotide codant pour ce polypeptide - Google Patents
Nouveau polypeptide, pterine-molybdene oxydoreductase humaine 12, et polynucleotide codant pour ce polypeptide Download PDFInfo
- Publication number
- WO2001075040A3 WO2001075040A3 PCT/CN2001/000426 CN0100426W WO0175040A3 WO 2001075040 A3 WO2001075040 A3 WO 2001075040A3 CN 0100426 W CN0100426 W CN 0100426W WO 0175040 A3 WO0175040 A3 WO 0175040A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- novel peptide
- peptide
- polynucleotide coding
- reduction enzyme
- disclosed
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- HNXQXTQTPAJEJL-UHFFFAOYSA-N 2-aminopteridin-4-ol Chemical compound C1=CN=C2NC(N)=NC(=O)C2=N1 HNXQXTQTPAJEJL-UHFFFAOYSA-N 0.000 title abstract 6
- 102000004190 Enzymes Human genes 0.000 title abstract 3
- 108090000790 Enzymes Proteins 0.000 title abstract 3
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 title abstract 3
- 229910052750 molybdenum Inorganic materials 0.000 title abstract 3
- 239000011733 molybdenum Substances 0.000 title abstract 3
- 230000033116 oxidation-reduction process Effects 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 238000012270 DNA recombination Methods 0.000 abstract 1
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne un nouveau polypeptide, une ptérine-molybdène oxydoréductase humaine 12, et un polynucléotide codant pour ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment des tumeurs malignes, de l'hémopathie, de l'infection par VIH, de maladies immunitaires et de diverses inflammations. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant pour la ptérine-molybdène oxydoréductase humaine 12.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU60015/01A AU6001501A (en) | 2000-03-27 | 2001-03-26 | A novel polypeptide, human pterine-molybdene oxydoreductase 12 and the polynucleotide encoding the polypeptide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00115149 CN1315520A (zh) | 2000-03-27 | 2000-03-27 | 一种新的多肽——人蝶呤钼氧化还原酶12和编码这种多肽的多核苷酸 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001075040A2 WO2001075040A2 (fr) | 2001-10-11 |
| WO2001075040A3 true WO2001075040A3 (fr) | 2002-03-07 |
Family
ID=4584618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000426 WO2001075040A2 (fr) | 2000-03-27 | 2001-03-26 | Nouveau polypeptide, pterine-molybdene oxydoreductase humaine 12, et polynucleotide codant pour ce polypeptide |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1315520A (fr) |
| AU (1) | AU6001501A (fr) |
| WO (1) | WO2001075040A2 (fr) |
-
2000
- 2000-03-27 CN CN 00115149 patent/CN1315520A/zh active Pending
-
2001
- 2001-03-26 WO PCT/CN2001/000426 patent/WO2001075040A2/fr active Application Filing
- 2001-03-26 AU AU60015/01A patent/AU6001501A/en not_active Abandoned
Non-Patent Citations (2)
| Title |
|---|
| DATABASE GENBANK [online] 23 November 1999 (1999-11-23), DODSWORTH S. ET AL., retrieved from GI:1183912 accession no. NCBI Database accession no. Z69374 * |
| DATABASE PROTEIN [online] 23 November 1999 (1999-11-23), CHAPMAN J. ET AL., retrieved from GI:5763838 accession no. NCBI Database accession no. (CAB53260) * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU6001501A (en) | 2001-10-15 |
| WO2001075040A2 (fr) | 2001-10-11 |
| CN1315520A (zh) | 2001-10-03 |
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